About George Papaliodis, MD

Board-certified in internal medicine and ophthalmology, Dr. George Papaliodis specializes in the treatment of systemic diseases that are associated with ocular inflammation. As the director of the Ocular Immunology and Uveitis Service, he treats patients with a range of ocular inflammatory disorders at Mass. Eye and Ear's main Charles Street campus and Stoneham satellite office, as well at Massachusetts General Hospital. In addition, as a member of the Comprehensive Ophthalmology and Cataract Consultation Service, he performs cataract surgery at Mass. Eye and Ear's Charles Street location.

While most of his time is devoted to patient care, Dr. Papaliodis has been involved in a number of research projects, including an investigation of LX-211 for the treatment of inflammatory eye diseases and a study of pulsed electromagnetic field therapy for the treatment of uveitis. He also investigated serum biomarkers in ocular sarcoidosis and was part of the Abbvie sponsored study evaluating Humira for the treatment of uveitis.

A renowned expert in ocular inflammatory diseases, Dr. Papaliodis has presented at many national and international conferences, including those hosted by the International Ocular Inflammation Society, the American College of Rheumatology, the Aegean Retina Society, the New England Ophthalmologic Society, the North Carolina Dermatology Society, the Dominican Republic National Ophthalmologic Society, the Association for Research in Vision and Ophthalmology, and SECO International.

In addition to establishing one of the largest ocular inflammatory disease practices in the country, he has played a critical role outlining the teaching curriculum in the field of uveitis/ocular inflammation for the residents at Harvard Medical School.

Departments, Centers, & Programs:

Clinical Interests:




Mass Eye and Ear at Stoneham
One Montvale Ave.
Suite 501
Stoneham, MA 02180
Phone: 617-936-6156

Mass Eye and Ear at Longwood
800 Huntington Ave.
Boston, MA 02115
Phone: 617-936-6156

Mass Eye and Ear
243 Charles St.
Boston, MA 02114
Phone: 617-936-6156

Medical Education

  • MD, University of Texas Southwestern Medical School
  • Residency, Massachusetts General Hospital
  • Residency, University of Texas Southwestern
  • Fellowship, Massachusetts Eye and Ear

American Board Certifications

  • Internal Medicine, American Board of Internal Medicine
  • Ophthalmology, American Board of Ophthalmology

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Dr. Papaliodis' research has focused on attempting to identify disease mechanisms that can induce uveitis and novel treatments for intraocular inflammation. He has studied serum biomarkers and genetics in ocular sarcoidosis along with the role of vitamin D in ocular inflammatory disorders.  He has been an investigator in multiple drug-company sponsored clinical trials to establish the efficacy of therapeutic agents for uveitis. In collaboration with Dr. John Kempen, he is currently assessing factors that may influence the development of ocular complications in those who have intraocular inflammation.


  • McKay KM, Borkar DS, Sevgi DD, Susarla G, Papaliodis GN, Sobrin L. Comparison of Modified Posterior Sub-Tenon's vs. Trans-Septal Triamcinolone Injection for Non-infectious Uveitis. Ocul Immunol Inflamm. 2020 Jan 04; 1-8.

    Minkus CL, Bispo PJM, Papaliodis GN, Sobrin L. Real-Time Multiplex PCR Analysis in Infectious Uveitis. Semin Ophthalmol. 2019; 34(4):252-255. 

    Noble CW, Gangaputra SS, Thompson IA, Yuan A, Apolo AB, Lee JM, Papaliodis GN, Kodati S, Bishop R, Magone MT, Sobrin L, Sen HN. Ocular Adverse Events following Use of Immune Checkpoint Inhibitors for Metastatic Malignancies. Ocul Immunol Inflamm. 2019 Apr 23; 1-6.

    Llop SM, Davoudi S, Stanwyck LK, Sathe S, Tom L, Ahmadi T, Grotting L, Papaliodis GN, Sobrin L. Association of Low Vitamin D Levels with Noninfectious Uveitis and Scleritis. Ocul Immunol Inflamm. 2019; 27(4):602-609. 

    Wolkow N, Papaliodis GN, Turalba AV. A 70-Year-Old Man With Pain and a Creamy Elevated Lesion After Transscleral Cyclophotocoagulation. JAMA Ophthalmol. 2018 02 01; 136(2):209-210.

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