About George Papaliodis, MD

Board-certified in internal medicine and ophthalmology, Dr. George Papaliodis specializes in the treatment of systemic diseases that are associated with ocular inflammation. As the director of the Ocular Immunology and Uveitis Service, he treats patients with a range of ocular inflammatory disorders at Mass. Eye and Ear's main Charles Street campus and Stoneham satellite office, as well at Massachusetts General Hospital. In addition, as a member of the Comprehensive Ophthalmology and Cataract Consultation Service, he performs cataract surgery at Mass. Eye and Ear's Charles Street location.

Dr. Papaliodis earned his medical degree and completed an ophthalmology residency at the University of Texas Southwestern School of Medicine. He went on to complete an additional residency in Internal Medicine at Harvard Medical School/Massachusetts General Hospital, followed by subspecialty training in ocular immunology and uveitis at Mass. Eye and Ear.

A renowned expert in ocular inflammatory diseases, Dr. Papaliodis has presented at many national and international conferences, including those hosted by the International Ocular Inflammation Society, the American College of Rheumatology, the Aegean Retina Society, the New England Ophthalmologic Society, the North Carolina Dermatology Society, the Dominican Republic National Ophthalmologic Society, the Association for Research in Vision and Ophthalmology, and SECO International.

Departments, Centers, & Programs:

Clinical Interests:




Hospital Medicine Unit
55 Fruit Street
Boston, MA 02114-2696

Massachusetts Eye and Ear
243 Charles Street
Boston, MA 02114 - 3002
Fax: 617-573-3181

Massachusetts Eye and Ear Stoneham
One Montvale Avenue
Suite 501
Stoneham, MA 02180

Medical Education

  • MD, UT Southwestern Medical School
  • Residency, Massachusetts General Hospital
  • Residency, UT Southwestern Medical Center
  • Fellowship, Massachusetts Eye & Ear

American Board Certifications

  • Internal Medicine, American Board of Internal Medicine
  • Ophthalmology, American Board of Ophthalmology

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Board-certified in internal medicine and ophthalmology, Dr. Papaliodis specializes in the treatment of systemic diseases that induce ocular inflammation. He has been the director of the Ocular Immunology and Uveitis service since 2005.  His research has focused on attempting to identify disease mechanisms which can induce uveitis and novel treatments for intraocular inflammation. He has studied serum biomarkers and genetics in ocular sarcoidosis along with the role of vitamin D in ocular inflammatory disorders.  He has been an investigator in multiple drug company sponsored clinical trials to establish the efficacy of therapeutic agents for uveitis.  In collaboration with Dr. John Kempen, he is currently working on assessing factors that may influence the development of ocular complications in those who have intraocular inflammation.