About James Stone, MD, PhD

Dr. Stone has published extensively on cardiovascular diseases including atherosclerosis, vasculitis, amyloidosis, and cardiomyopathies. He is a founding co-chair of the Standards and Definitions Committee of the Society for Cardiovascular Pathology, and directs the core laboratory of an NIH-funded multi-center study of cardiac allograft rejection.  He is a member of the Center for Systems Biology, where his laboratory studies basic mechanisms relating to the cellular and molecular biology of cardiovascular diseases

Departments, Centers, & Programs:

Clinical Interests:



Mass General Pathology
55 Fruit St.
Boston, MA 02114
Phone: 617-643-0800

Medical Education

  • M.D.; Ph.D., University of Michigan Medical School
  • Residency, Brigham and Women's Hospital
  • Residency, Brigham and Women's Hospital
  • Fellowship, Brigham and Women's Hospital
  • Fellowship, Brigham and Women's Hospital

American Board Certifications

  • Anatomic Pathology, American Board of Pathology

Accepted Insurance Plans

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My lab focuses on elucidating the mechanisms of cardiac and vascular diseases. We are working to understand the biochemical processes resulting in atherosclerosis. Investigations are focused on signal transduction mechanisms responsible for the pre-atherosclerotic intimal hyperplasia, and the factors stimulating the formation of intimal necrotic/lipid cores. For more details, visit the Stone Lab. For information about research concepts, co-authors, and to see a timeline, visit Dr. Stone's profile at the Harvard Clinical and Translational Science Center.


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