Novel biomaterial prevents rejection of transplants for type 1 diabetes
Clinical trial is planned based on results from preclinical study.
Contact Information
James F. Markmann MD, PhD is the Chief of the Division of Transplant Surgery and Director of Clinical Operations at the Transplant Center at Massachusetts General Hospital, and the Claude Welch Professor of Surgery at Harvard Medical School. He specializes in liver, kidney, pancreas and islet transplantation as well as hemodialysis access surgery. He is active in numerous societies, editorial boards and organizations and is currently secretary of the International Pancreas and Islet Transplant Association and Councilor of the American Society of Transplant Surgeons. He has published more than 300 scientific papers over the last 30 years, most in the area of immune tolerance and pancreas and islet transplantation and has held continuous NIH R01 funding for >15 years. His current research interests include: 1) understanding the mechanism of action and therapeutic potential of regulatory B cells, 2) exploring the potential of ex vivo liver perfusion to improve marginal organ function, and 3) clinical trials in transplantation tolerance and pancreatic islet transplantation.
Clinical Interests:
Treats:
Mass General Transplant Center
55 Fruit St.
Boston, MA 02114
Phone: 617-726-2000
Mass General Vascular Center
55 Fruit St.
Gray Building
Boston, MA 02114
Phone: 617-643-0765
Massachusetts General Hospital
55 Fruit St.
Boston, MA 02114
Phone: 617-726-2000
Medical Education
American Board Certifications
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Dr. Markmann's research interests include 1) developing ways to perform transplants without immunosuppression, 2) new approaches to alleviate the organ shortage, and 3) utilizing pancreatic islets to treat patients with Type I diabetes. Dr. Markmann has published over 250 scientific papers and his research work is funded by the NIH and JDRF.
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Mass General is the #1 hospital in New England based on U.S. News & World Report Best Hospitals for 2022-2023.
Clinical trial is planned based on results from preclinical study.
A team of surgeons and specialists at Mass General is announcing an achievement in transplant surgery today, having recently performed the largest number of adult heart transplants in the country using what are known as Donation after Circulatory Death (DCD) donor hearts.