About Jonathan Passeri, MD

Jonathan J. Passeri, MD, is a graduate of the College of the Holy Cross and New York Medical College.  He completed his residency in Internal Medicine at Massachusetts General Hospital, followed by fellowships in Cardiovascular Disease and Advanced Echocardiography at Massachusetts General Hospital.  He joined the staff of Massachusetts General Hospital in 2007 as a staff member of the Cardiology Division and the Cardiac Ultrasound Laboratory.  Currently, Dr. Passeri is the medical director of the Massachusetts General Hospital Heart Valve Program and director of Interventional Echocardiography within the Cardiac Ultrasound Laboratory.

Dr. Passeri's main clinical focus is on the evaluation and management of valvular heart disease.  He is a co-investigator in the PARTNER Trial, a pivotal clinical trial of transcatheter aortic valve replacement for patients with calcific aortic stenosis.  Dr. Passeri also works closely with members of the cardiac catheterization laboratory in using advanced echocardiographic techniques to guide a variety of complex transcatheter structural heart procedures.  Dr. Passeri lectures each year in a variety of Harvard Medical School's continuing education courses in cardiology.

Clinical Interests:



Mass General Heart Center
55 Fruit St.
Boston, MA 02114
Phone: 866-644-8910

Medical Education

  • MD, New York Medical College
  • Residency, Massachusetts General Hospital
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Cardiovascular Disease, American Board of Internal Medicine

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Dr. Passeri's research focuses primarily on valvular heart disease and echocardiography.  He is a co-investigator in the PARTNER Trial, a pivotal clinical trial of transcatheter aortic valve replacement for patients with calcific aortic stenosis.


  • Select Publications:

    • Jagannath AD, Johri AM, Liberthson R, Larobina M, Passeri J, Tighe D, Agnihotri AK. Quadricuspid Aortic Valve: A Report of 12 Cases and a Review of the Literature. Echocardiography 2011 Aug 19
    • PARTNER Trial Investigators. Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients. New Eng J Med 2011 Jun 9;364(23):2187-98.
    • Johri AM, Rojas CA, El-Shereif A, Witzke CF, Chitty DW, Palacios IF, Passeri J, King ME, Abarra S. Imaging of Atrial Septal Defects: Echocardiography and CT Correlation. Heart 2011;97:1441-1453.
    • Johri AM, Witzke C, Solis J, Palacios IF, Inglessis I, Picard MH, Passeri J. Real-Time Three-dimensional Transesophageal Echocardiography in Patients with Secundum Atrial Septal Defects: Outcomes Following Transcatheter Closure. J Am Soc Echocardiography 2011 Apr;24(4):431-7.
    • Johri AM, Passeri J, Picard MH. Three-dimensional echocardiography: Approaches and clinical utility. Heart. 2010;96(5):390-7.
    • Johri AM, Yared K, Durst R, Cubeddu RJ, Palacios IF, Picard MH, Passeri J. Three-dimensional echocardiography-guided repair of severe paravalvular regurgitation in a bioprosthetic and mechanical mitral valve. Eur J Echocardiography. 2009;10:572-5.
    • Kristo J, Hardy GJ, Anderson TJT, Sinha S, Ahluwalia N, Lin AY, Passeri J, Scherrer-Crosbie M, Gerszten RE. Pharmacological inhibition of BLT1 diminishes early abdominal aneurysm formation. Atherosclerosis 2010 May;210(1):107-13.


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