About Anthony Iafrate, MD, PhD

Dr. Iafrate is a Professor of Pathology at Harvard Medical School, former Director of the Center for Integrated Diagnostics (CID), a clinical laboratory for molecular diagnostics at Massachusetts General Hospital and is currently the Vice Chair of Academic Affairs at the Massachusetts General Hospital (MGH). Dr. Iafrate received his MD/PhD dual degree from the State University of New York at Stony Brook in 2000 and was trained in anatomic and molecular genetic pathology at Brigham and Women’s Hospital. Dr. Iafrate is a board-certified Pathologist and has been on staff at MGH since 2005. The CID provides rapid personalized genomic testing to help inform cancer treatment decisions for patients. His research is focused on lung and brain tumors, where he has been closely involved in the clinical development of crizotinib and companion diagnostics in ALK- and ROS1 positive lung cancers. His lab has developed several technologies for sequencing tumors, including SNaPshot and the next-generation sequencing-based Anchored Multiplex PCR, both techniques have been widely used in the molecular diagnostics community.

Clinical Interests:



Mass General Pathology
55 Fruit St.
Boston, MA 02114
Phone: 617-643-0800

Medical Education

  • MD, State University of New York, Stony Brook School of Medicine And Biomedical Sciences
  • Residency, Brigham and Women's Hospital
  • Fellowship, Brigham and Women's Hospital

American Board Certifications

  • Anatomic Pathology, American Board of Pathology
  • Molecular Genetic Pathology, American Board of Medical Genetics and Genomics

Accepted Insurance Plans

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Research in the Iafrate laboratory focuses on bringing new genetic technologies to cancer diagnostics and their application to the practice of pathology. Initially research focused on lung cancer, but our approach is expanding to all malignancies. For more information about research concepts, co-authors, and to see a timeline, visit  Dr. Iafrate's profile at the Harvard Clinical and Translational Science Center.


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