Boston, MAPhone: 855-644-6387
About U. Shivraj Sohur, MD, PhD
- Complex neurological disorders
- Movement disorders
- Parkinson's and related parkinsonian disorders
- Tremor; essential tremor; medication-related tremor
- French, Hindi, Urdu
Mass General Neurology
55 Fruit St.
Boston, MA 02114
- MD, Vanderbilt University School of Medicine
- PhD, Vanderbilt University School of Medicine
- Residency, Beth Israel Deaconess Medical Center
- Fellowship, Massachusetts General Hospital*****
American Board Certifications
- Neurology, American Board of Psychiatry and Neurology
Accepted Insurance Plans
- Aetna Health Inc.
- Beech Street
- Blue Cross Blue Shield - Blue Care 65
- Blue Cross Blue Shield - Indemnity
- Blue Cross Blue Shield - Managed Care
- Blue Cross Blue Shield - Partners Plus
- BMC HealthNet Mass Health MCO/ACO
- Cigna (PAL #'s)
- Commonwealth Care Alliance
- Fallon Community HealthCare
- Great-West Healthcare (formally One Health Plan)
- Harvard Pilgrim Health Plan - ACD
- Harvard Pilgrim Health Plan - PBO
- Health Care Value Management (HCVM)
- Humana/Choice Care PPO
- Maine Community Health Options (MCHO)
- Mass General Brigham Health Plan - ACD
- Mass General Brigham Health Plan - PBO
- Medicare - ACD
- Medicare ACO - ACD
- Medicare ACO - PBO
- OSW - Maine
- OSW - New Hampshire
- OSW - Rhode Island
- Private Health Care Systems (PHCS)
- Senior Whole Health
- Tufts Health Plan
- United Healthcare (non-HMO) - ACD
- United Healthcare (non-HMO) - PBO
- Well Sense Pediatrics
Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.
Parkinson's disease (PD) is currently an incurable, chronic and debilitating basal ganglia disorder, centrally due to the degeneration of midbrain dopaminergic neurons (mesDA) subtypes, with closely related types of neurons also implicated in secondary ways. The overarching hypothesis of this work is that understanding the molecular-genetic mechanisms of the precise initial development of mesDA subtypes will potentially contribute importantly in cellular replacement and circuit repair or modulation strategies of vulnerable circuitry. Identifying the molecular-genetic controls over subtype-specific generation and differentiation of such mesDA subtypes likely represents a critical step for the development of cellular replacement / circuit repair strategies in PD, since key developmental programs are re-initiated in the adult CNS upon neuronal loss.
In the laboratory, by using innovative approaches such as microsurgery in PD models, fluorescence activated cell sorting (FACS) and state of the art molecular neuroscience, Dr. Sohur and his group investigate how different populations of mesDA develop in the brain. By understanding the molecular mechanisms of the subtype specificity of mesDA with precision, it is hoped that, down the road, we will translate these findings to help our patients with PD.
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