Research at the Mass General is interwoven throughout more than 30 departments, centers and units, and is conducted with the support and guidance of the Mass General Research Institute.
John Higgins, MD
John Higgins, MD
Associate Professor of Systems Biology, Harvard Medical School
Departments, Centers, & Programs:
55 Fruit Street
Boston, MA 02114-2696
- MD, Harvard Medical School/ BWH
- Residency, Brigham and Women's Hospital
- Fellowship, Brigham and Women's Hospital
American Board Certifications
- Clinical Pathology, American Board of Pathology
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Dr. Higgins studies the dynamics of human pathophysiologic processes by developing mathematical descriptions of complex human disease phenotypes and how they change over time.
See details at the Higgins Lab.
View a complete list of Dr. Higgins' publications on the Center for Systems Biology website.
- Patel H, Patel H, Higgins JM. Modulation of Red Blood Cell Population Dynamics is a Fundamental Homeostatic Response to Disease. American Journal of Hematology. 2015 Feb 18
- Malka R, Delgado FF, Manalis SR, Higgins JM. In Vivo Volume and Hemoglobin Dynamics of Human Red Blood Cells. PLoS Computational Biology, 10:e1003839 (2014).
- Higgins, JM* Mahadevan, L. Physiological and pathological population dynamics of circulating human red blood cells. Proceedings of the National Academy of Sciences of the United States of America 107:20587-20592 (2010).
- Higgins JM and Sloan SR. Stochastic Modeling of Human RBC Alloimmunization: Evidence for a Distinct Population of Immunologic Responders. Blood. 112:2546-53 (2008).