About Wendy Macias Konstantopoulos, MD, MPH, MBA

Dr. Wendy Macias-Konstantopoulos, MD, MPH is Associate Professor of Emergency Medicine at Harvard Medical School and attending physician in the Department of Emergency Medicine at Massachusetts General Hospital (MGH). She completed a Global Health Leadership Fellowship at MGH and earned her Master of Public Health degree from Harvard School of Public Health. Dr. Macias-Konstantopoulos is the MGH Endowed Scholar for Leadership in Emergency Medicine and Director of the Center for Social Justice and Health Equity in the MGH Emergency Department’s (ED). She is founding Executive Director of the Mass General Freedom Clinic, an innovative primary and preventative health care clinic for human trafficking victims and survivors that won the 2014 Partnership for Freedom national competition. The Mass General Freedom Clinic also serves as the medical home for a unique MGH collaboration with the nonprofit Hostage US, through which trauma-informed medical care and care coordination is provided for repatriated American captives and their families.

Dr. Macias-Konstantopoulos is particularly interested in public health and population management interventions that address social determinants of disease and improve the health and well-being of underserved patients and communities. She is a member of the Medicaid ACO leadership team in the ED which places special attention on interdisciplinary complex patient care coordination. She was site PI for a large NIH-funded randomized controlled trial of an ED-based brief intervention for substance use, and is active with current hospital efforts to reduce the unmet health and social needs of patients. Her current research and programmatic efforts focus on expanding knowledge and closing the challenging structural gaps that perpetuate health disparities. In addition, Dr. Macias-Konstantopoulos is the 5-term elected Chair of the Massachusetts Medical Society’s Committee on Violence Intervention and Prevention and serves various state and federal groups engaging in education and policy advocacy efforts on behalf of trafficked individuals.

Departments, Centers, & Programs:

Clinical Interests:




Mass General Emergency Medicine
55 Fruit St.
Boston, MA 02115
Phone: 617-724-4100

Medical Education

  • MD, University of Vermont College of Medicine
  • Residency, Brigham and Women's Hospital

American Board Certifications

  • Emergency Medicine, American Board of Emergency Medicine

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Dr. Macias serves as PI on a study on sex trafficking of women and girls in the Boston area, and as site PI on a federally-funded study on ED-based interventions for drug abuse.


  • Select Publications:

    • Wexler D, Macias Konstantopoulos W, Forcione D, Xiong L, Cauley C, Pierce K. A 36-Year-Old Man with Episodes of Confusion and Hypoglycemia. N Engl J Med. 2018; 379(4):376-85.
    • Duber HC, Barata IA, Cioè-Peña E, Liang SY, Ketcham E, Macias-Konstantopoulos W, Ryan SA, Stavros M, Whiteside LK. Identification, Management, and Transition of Care for Patients with Opioid Use Disorder in the Emergency Department. Ann Emerg Med. 2018; 72(4):420-31.
    • Judge AM, Murphy JA, Hidalgo J, Macias-Konstantopoulos W. Engaging Survivors of Human Trafficking: Complex Health Care Needs and Scarce Resources. Ann Intern Med. 2018; 168(9):658-63.
    • Barata IA, Shandro J, Polansky R, Sachs C, Duber HC, Weaver L, Heins A, Owen HS, Josephson EB, Macias-Konstantopoulos W. Systematic Review of Emergency Department Effectiveness in Screening, Intervention, and Referral to Treatment for Alcohol Use Disorders. West J Emerg Med. 2017; 18(6):1143-52.
    • Macias-Konstantopoulos W. Human Trafficking: The Role of Medicine in Interrupting the Cycle of Abuse and Violence. Ann Intern Med. 2016; 165(8):582-8.

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