About Stacey Gray, MD

Dr. Stacey Gray is an ear, nose, and throat doctor with fellowship training in rhinology and endoscopic sinonasal and skull base surgery. Her clinical interests include diseases of the nose and sinuses and endoscopic approaches to the skull base.

Dr. Gray, alongside Dr. Eric Holbrook, developed the Sinus Center at Mass. Eye and Ear with the goal to synthesize comprehensive management for patients presenting with complex chronic rhinosinusitis (CRS). Each year, the Sinus Center treats more than 10,000 patients.

Dr. Gray has been an invited speaker at national and international meetings to lecture on endoscopic management of sinonasal and skull base pathology as well as surgical education and has published more than 60 peer-reviewed papers in the field. She serves on the editorial board of the American Journal of Rhinology and Allergy, the Instructional Course Advisory Committee for the American Academy of Otolaryngology–Head and Neck Surgery, and as Chair of the Membership Committee of the American Rhinologic Society.

In 2015, she was the recipient of the Harvard Medical School Young Mentor Award for her contributions to teaching and education.

Departments, Centers, & Programs:

Clinical Interests:



Mass General Cancer Center: Neuro-Oncology
55 Fruit St.
Yawkey Center for Outpatient Care
Boston, MA 02114
Phone: 617-726-5130

Mass Eye and Ear
243 Charles St.
Boston, MA 02114
Phone: 617-523-7900

Medical Education

  • MD, Georgetown University School of Medicine
  • Residency, Massachusetts Eye and Ear
  • Fellowship, Massachusetts Eye and Ear

American Board Certifications

  • Otolaryngology-Head and Neck Surgery, American Board of Otolaryngology

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Dr. Gray's research investigates the current approaches to treating chronic rhinosinusitis, particularly for patients with a prior history of radiation therapy and surgery for sinonasal malignancies. She is interested in how these treatments impact long-term sinonasal quality of life. Additionally, Dr. Gray has collaborated with Dr. Daniel Hamilos, an allergist-immunologist at MGH, pursuing research efforts in the area of innate mucosal immunity of the paranasal sinuses.


  • Selected Publications:

    Yamin M, Holbrook EH, Gray ST, Harold R, Busaba N, Sridhar A, Powell KJ, Hamilos DL. Cigarette smoke combined with Toll-like receptor 3 signaling triggers exaggerated epithelial regulated upon activation, normal T-cell expressed and secreted/CCL5 expression in chronic rhinosinusitis. J Allergy Clin Immunol. 2008 Dec;122(6):1145-1153.

    Gray ST, Chen YL, Lin DT. Efficacy of Proton Beam Therapy in the Treatment of Ewing's Sarcoma of the Paranasal Sinuses and anterior skull base. Skull Base. 2009 November; 19(6):409-416.

    Shin JJ, Shapiro J, Gray ST, Cunningham M. Validation of Clinical Practice Ability Instrument. Otolaryngology-Head and Neck Surg. 2010 Apr;142(4):493-9.el.

    Gray S, Shin J, Metson R. Oral antibiotic therapy for one month or longer: Impact on sinonasal symptoms, quality of life. Evidence-based Otolaryngology. New York, NY: Springer;2008.

    Gray S, Shin J, Metson R. Aerosolized antibiotics: Impact on sinonasal outcomes. Evidence-based Otolaryngology. New York, NY: Springer;2008.

    Gray S, Shin J, Metson R. Intranasal antifungal therapy: Impact on computed tomography, symptoms, quality of life, and endoscopy. Evidence-based Otolaryngology. New York, NY: Springer;2008.

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