About Zachary Wallace, MD, MSC

Zachary Wallace, MD, MS is a graduate of Cornell University and Georgetown University School of Medicine.  He completed his medicine residency and rheumatology fellowship at Massachusetts General Hospital.  During fellowship, he completed a Masters of Science in Epidemiology at the Harvard TH Chan School of Public Health.  Following fellowship, he joined the Rheumatology Unit in the Division of Rheumatology, Allergy, and Immunology. In addition to seeing patients in the Rheumatology Clinic and the Rheumatology-Dermatology Clinic, Dr. Wallace receives grant funding to conduct clinical epidemiology research in IgG4-related disease (IgG4-RD) and ANCA-associated vasculitis (AAV).  His clinical interests include IgG4-RD as well as AAV.  He is a member of the Center for IgG4-Related Disease at MGH as well as the Vasculitis and Glomerulonephritis Center at MGH. 

Departments, Centers, & Programs:

Clinical Interests:



Mass General Rheumatology
55 Fruit St.
Yawkey Center for Outpatient Care
Suite 4B
Boston, MA 02114
Phone: 617-726-7938

Medical Education

  • MD, Georgetown University School of Medicine
  • Residency, Massachusetts General Hospital
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Internal Medicine, American Board of Internal Medicine
  • Rheumatology, American Board of Internal Medicine

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Dr. Zachary Wallace conducts clinical epidemiology research with a focus on multi-system rheumatic diseases, especially IgG4-related disease (IgG4-RD) and ANCA-associated vasculitis (AAV).  He has received advanced training in clinical epidemiology through a Masters of Science in Epidemiology from the Harvard TH Chan School of Public Health. Dr. Wallace has conducted research and provided clinical care for patients with IgG4-RD since the beginning of his residency. He is a member of the Center for IgG4-RD which is an NIH Autoimmune Center of Excellence. His research in IgG4-RD is focused on the epidemiology of the disease, clinical trials, and outcome tool development. In AAV, he is interested in improving long-term outcomes, including mortality, cardiovascular disease, and end-stage renal disease, through the application of advanced clinical and pharmacoepidemiology to identify optimal treatment regimens.  His research has been funded by the National Institutes of Health, the Rheumatology Research Foundation, and the Executive Committee on Research at MGH.  


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