About Mike Osborne, MD

Dr. Michael Osborne is a cardiologist at Massachusetts General Hospital, Associate Director of Nuclear Cardiology: Education at Massachusetts General Hospital, and Assistant Professor of Medicine at Harvard Medical School. He graduated summa cum laude with membership in Tau Beta Pi with a degree in biomedical engineering from Vanderbilt University in 2006. He subsequently graduated with honors and membership in the Gold Humanism Honor Society and Alpha Omega Alpha from the University of Chicago Pritzker School of Medicine in 2010. Dr. Osborne completed his internship and residency in internal medicine at the Brigham and Women’s Hospital, Harvard Medical School in 2013. He completed his clinical and research fellowships in cardiovascular medicine and cardiovascular imaging at the Massachusetts General Hospital in 2018. 

Dr. Osborne’s research uses advanced cardiovascular imaging techniques, especially positron emission tomography, to investigate the mechanisms linking psychosocial and environmental stressors to cardiometabolic diseases and to identify early markers of cardiovascular risk. In addition, he is interested in using imaging to characterize the impact of interventions on the link between chronic stress and cardiometabolic disease. Beyond his research, Dr. Osborne is a clinician with interests in nuclear cardiovascular imaging and preventive cardiology.

Clinical Interests:



Mass General Heart Center
55 Fruit St.
Boston, MA 02114
Phone: 866-644-8910

Medical Education

  • MD, University of Chicago, Pritzker School of Medicine
  • Residency, Brigham and Women's Hospital
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Cardiovascular Disease, American Board of Internal Medicine
  • Internal Medicine, American Board of Internal Medicine
  • Nuclear Cardiology, APCA - Alliance for Physician Certification & Advancement

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Cardiometabolic disease has emerged as a growing public health problem across the world. While a large proportion of cardiometabolic disease risk arises from heritable factors and health behaviors, it has hypothesized for years that psychosocial and environmental stressors contribute to the development of these pathologies. Nevertheless, the mechanisms are incompletely defined. Dr. Osborne's research implements advanced cardiovascular imaging, specifically positron emission tomography, to: 1) understand the mechanisms that link psychosocial and environmental stressors to cardiometabolic diseases, 2) identify early markers of cardiometabolic risk, and 3) evaluate the effect of interventions on imaging biomarkers of cardiometabolic diseases.


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