About Nisse Clark, MD, MPH

I am a fellowship-trained Minimally Invasive Gynecologic Surgeon and Board-Certified Obstetrician and Gynecologist. I specialize in minimally-invasive procedures for women with complex pathology such as large uteri, fibroids, advanced endometriosis, pelvic adhesive disease, or who have multiple medical comorbidities. I commonly perform laparoscopic hysterectomy, myomectomy, endometriosis surgery, adnexal surgery and hysteroscopy. I also have an interest in Essure removal, C-section defect repair and laparoscopic cerclage.

My training includes a two-year fellowship in Minimally Invasive Gynecologic Surgery at Brigham and Women’s Hospital and a residency in Obstetrics and Gynecology at Tufts Medical Center. I also completed a Master of Public Health with a focus in Clinical Effectiveness at the Harvard T.H. Chan School of Public Health. I obtained my medical degree at Loyola University Stritch School of Medicine and my undergraduate degree in Biological and Environmental Engineering at Cornell University.

Outside of the operating room, my time is dedicated to clinical research and teaching. I am also an active member of my field’s national organization, the American Association of Gynecologic Laparoscopists. I am native to Boston where I currently reside with my family.


Clinical Interests:



Boston: Massachusetts General Hospital

Vincent Gynecology Service
55 Fruit Street
Boston, MA 02114-2696
Phone: 617-724-6850

View location, directions and parking information for Mass General

Waltham: Mass General Waltham

Mass General Waltham OB/GYN Service
52 Second Avenue, Suite 402
Waltham, MA 02451
Phone: 781-487-3860
Fax: 781-487-3870

Medical Education

  • MD, Loyola University Stritch School of Medicine
  • Residency, Tufts Medical Center
  • Fellowship, Brigham and Women's Hospital

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


My research interests involve minimally-invasive surgical techniques for the treatment of fibroids, abnormal uterine bleeding, endometriosis and pelvic pain, with a focus on patient-centered outcomes and optimal perioperative care.


  • View my most recent publications at PubMed

    Selected Publications:

    1. Clark NV, Einarsson JI. A Novel Technique for Essure Reversal. JSLS. 2019;23(1).
    2. Clark NV, Pepin KJ, Einarsson JI. Surgical skills assessment tools in gynecology. Curr Opin Obstet Gynecol. 2018 Oct;30(5):331-336.
    3. Clark NV, Wang KC, Opoku-Anane J, Hill-Lydecker CI, Vitonis AF, Einarsson JI, Cohen SL. The menstrual cycle and blood loss during laparoscopic myomectomy. Acta Obstet Gynecol Scand. 2017 Dec;96(12):1446-52.
    4. Clark NV, Gujral H, Wright KN. Impact of a Fellowship-Trained Minimally Invasive Gynecologic Surgeon on Patient Outcomes. JSLS. 2017 Jul – Sep;21(3).
    5. Clark NV, Endicott SP, Jorgensen EM, Hur H, Lockrow EG, Kern ME, Jones-Cox CE, Dunlow SG, Einarsson JI, Cohen SL. Review of Sterilization Techniques and Clinical Updates. J Minim Invasive Gynecol. 2018 Nov – Dec;25(7)1157-1164.
    6. Clark NV, Cohen SL. Tissue Extraction Techniques During Uterine Surgery. J Minim Invasive Gynecol. 2018 Feb;25(2):251-256.
    7. Clark NV, Einarsson JI. Independent Roll-Down Ring for Contained Tissue Extraction. J Minim Invasive Gynecol. 2017 Nov – Dec;24(7):1227-1228.
    8. Clark NV, Rademaker D, Mushinski AA, Ajao MO, Cohen SL, Einarsson JI. Essure Removal for the Treatment of Device-Attributed Symptoms: An Expanded Case Series and Follow-up Survey. J Minim Invasive Gynecol. 2017 Sep – Oct;24(6):971-976.