Bacterial Pathogenesis

Learn about research studies and clinical trials conducted by the Division of Infectious Disease in the area of bacterial pathenogenesis.

Molecular interactions of bacterial pathogens with host cells

• Amy Barczak, MD: Tuberculosis pathogenesis in cells and tissues
• Marcia Goldberg, MD: Bacterial host-pathogen interactions and rapid diagnostics of infection
• Deborah Hung, MD, PhD: In vivo mechanisms of bacterial pathogenesis and infectious disease diagnostics
• Matthew Waldor, MD, PhD: Investigation of pathogen-host interactions in the context of animal models of infection

Immune response to bacterial pathogens

• Roby Bhattacharyya, MD, PhD: Single-cell immune profiling in sepsis
• Richelle Charles, MD: Human immune responses to cholera and typhoid fever
• Joseph ElKhoury, MD: Role of the innate immune system in neurodegeneration, inflammation, and infection
• Marcia Goldberg, MD: Bacterial host-pathogen interactions and rapid diagnostics of infection
• Jason Harris, MD: Human immune response to cholera and cholera vaccines
• Dennis Kasper, MD: Immune-pathogen interactions
• Regina LaRocque, MD, MPH: Host factors influencing susceptibility to cholera in endemic settings
• Gerald Pier, PhD: Virulence and immunity to microbial pathogens
• Edward Ryan, MD, DTM&H: Host-pathogen interactions, immune reponses and vaccine development for bacterial pathogens
• Matthew Waldor, MD, PhD: Investigation of pathogen-host interactions in the context of animal models of infection
• H. Shaw Warren, MD: Pathogenesis and treatment of sepsis and induced secondary inflammation

Microbiota

• Elizabeth Hohmann, MD: Fecal transplantation for C. difficile and other indications
• Dennis Kasper, MD: Immune-pathogen interactions
• Regina LaRocque, MD, MPH: Host factors influencing susceptibility to cholera in endemic settings
• Cammie Lesser, MD, PhD: Bacterial host-pathogen interactions and the development of designer probiotics as therapeutics
• Gerald Pier, PhD: Virulence and immunity to microbial pathogens
• Matthew Waldor, MD, PhD: Investigation of pathogen-host interactions in the context of animal models of infection