Research Spotlight: Understanding More About the Genetic Drivers of Airway Defects in Job Syndrome
Researchers sought to determine whether and how AD-HIES STAT3 mutations impact innate host defense and regeneration of airway epithelial cells.
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NewsMar | 5 | 2020
Delirium is a sudden state of confusion, inattention, and change in one’s ability to think clearly.
Delirium occurs in one in three patients 65 years and older who are hospitalized. It is most common in patients who are very sick – like those in the intensive care unit – or those with underlying medical problems, but can occur in any patient in any setting.
People who develop delirium are more likely to stay in the hospital longer, be discharged to a rehab or nursing home rather than their own home and have trouble participating in their recovery. Because of this, delirious patients have a higher risk of death and permanent disability. Some patients with delirium will suffer with confusion for weeks to months after discharge and require ongoing support and care.
Delirium comes on suddenly (hours-days) and can often be reversed if addressed promptly. Some people with delirium are agitated while others are very sleepy. Some have periods of agitation mixed with times of sedation.
Dementia is a condition that comes on slowly - usually over years - and is not reversible. Patients with dementia often show memory problems and difficulty with daily tasks. Their ability to remember and do their daily tasks will gradually worsen over years.
It’s important to recognize patients with delirium as soon as they show signs of the condition, and to target preventive strategies to those at the highest risk of developing delirium. Some proven strategies include staying hydrated and nourished, getting enough sleep, and keeping the body and mind active while avoiding unnecessary medications.
Researchers sought to determine whether and how AD-HIES STAT3 mutations impact innate host defense and regeneration of airway epithelial cells.
Boston Magazine has named 82 physicians and surgeons affiliated Mass General for Children to its annual Top Doctors report. This award recognizes their commitment to providing outstanding, personalized care for infants, children and adolescents throughout the community.
The process of getting a drug to patients is cumbersome and heroic. For Drs. Sonia Vallabh and Eric Minikel, their path has been, they say, like “driving at night in the fog."
Providers at Mass General are taking steps to make care more effective, empowering and even enjoyable for patients.
Unsafe prediction failure occurs when a ML system produces an erroneous prediction, and either fails to convey a lack of confidence in the prediction or deceitfully conveys a high level of confidence in its correctness.
Using a multivariate artificial intelligence (AI) model initially developed to predict the risk of high-flow oxygen therapy or mechanical ventilation requirement during the COVID-19 pandemic.