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One of Dr. Cetrulo’s primary goals is to develop a protocol for tolerance of hand and face transplantation to eliminate the need for immunosuppression. Transplant tolerance has been achieved in kidney, lung, combined heart-kidney transplantation in large animal research at the Center for Transplantation Sciences (CTS) at the Massachusetts General Hospital (MGH), where he is currently a Senior Investigator and Head of the Vascularized Composite Allotransplantation (VCA) Laboratory. This tolerance protocol has been successfully translated to kidney transplant patients in the Transplant Unit at MGH. Dr. Cetrulo intends to modify this protocol to apply it to VCA. As a reconstructive plastic surgery attending at the MGH, he is also in an ideal situation to see this research translated directly from bench to bedside.
45 doctors from Massachusetts General Hospital’s Department of Surgery included in Boston magazine's 2019 Top Doctors list.
“Today, I begin a new chapter filled with personal hope and hope for others who have suffered genital injuries, particularly for our service
members who put their lives on the line and suffer serious damage as a
result,” says Thomas Manning, 64, who, earlier this month, received the
nation’s first penis transplant at the MGH. “If you tell the truth, you have
nothing to worry about. I’m not ashamed at all.”
A team of surgeons at Massachusetts General Hospital announced today that they have performed the nation's first genitourinary reconstructive (penile) transplant.
A specially-bred strain of miniature swine lacking the molecule responsible for the rapid rejection of pig-to-primate organ transplants may provide a new source of skin grafts to treat seriously burned patients.
A procedure developed at the MGH to induce immune tolerance to organ transplants has now been shown to also induce tolerance to model tissue transplants in miniature swine.
Making an important step towards greater availability of hand and face transplants, MGH investigators have shown that a procedure developed to induce immune tolerance to organ transplants can induce tolerance to a model limb transplant in miniature swine.
Jonathan Winograd, MD, and Curtis L. Cetrulo Jr, MD, discuss how Joe Kinan, a Station nightclub fire survivor, became the first hand transplant recipient at Massachusetts General Hospital.
On Oct. 26, 19 days after becoming the MGH’s first hand transplant recipient, Joe Kinan showed how his unwavering commitment to having a positive attitude has paid off – he wiggled the fingers on his left hand for the first time in public.
The first successful replantation of a human limb took place at the MGH in 1962. Now, nearly 50 years later, the Division of Plastic and Reconstructive Surgery is in the process of reviewing potential candidates for the latest in medical advances – hand transplantation surgery.
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