Collaborative Center for X-linked Dystonia Parkinsonism - Massachusetts General Hospital, Boston, MA

About Us

An international consortium of scientists, physicians and advocates working to advance research and clinical care for people with XDP.

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An International Approach

The Collaborative Center for X-linked Dystonia Parkinsonism (XDP), based at Massachusetts General Hospital, brings together an international team of experts to advance our understanding and ability to treat this debilitating neurodegenerative disease.

Meet Our Team

Our Mission

Our mission is to identify the genetic substrates and cellular mechanisms that contribute to XDP pathogenesis, to characterize the natural history and prevalence of XDP and to improve the delivery of care to XDP patients by expanding clinical resources and training.

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What is X-linked Dystonia Parkinsonism

X-linked dystonia parkinsonism (XDP) is an adult-onset, genetic movement disorder that almost entirely affects males who descend from the island of Panay in the Philippines.

Contact Us

Collaborative Center For X-Linked Dystonia Parkinsonism
Building 114
Charlestown Navy Yard
16th Street

Charlestown, MA 02129

Near Public Transit
Handicapped Accessible

Phone: 617-643-5007
Email: xdp@partners.org

News

A large international collaborative effort culminates in publication in journal Cell, Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly
The XDP Center welcomes three distinguished scientists to its Scientific Advisory Board:
Ann Graybiel, PhD (MIT), Jang-Ho Cha, MD, PhD (Novartis) and Danilo Tagle, PhD, MS (NIH)
Mass General team identifies DNA element that may cause rare movement disorder. Number of DNA repeats correlated with age of onset for X-linked dystonia parkinsonism
Dr. Aloysius Domingo, postdoctoral Fellow with the Collaborative Center for XDP, is awarded with the Mahlon Delong Young Investigator Award from the Dystonia Medical Research Foundation.
A new publication from the laboratory of Cristopher Bragg, PhD at MGH describes altered NFκB signaling in cells derived from XDP patients.
Laurie J. Ozelius, PhD, is awarded the second annual Bachmann-Strauss Prize for Excellence in Dystonia Research from the Michael J. Fox Foundation for Parkinson’s Research
Xandra Breakfield, PhD, is awarded the Bachmann-Strauss Prize for Excellence in Dystonia Research from the Michael J. Fox Foundation for Parkinson’s Research

EVENTS

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Mass General is poised to change the future through X-linked dystonia parkinsonism research. With your support, we can accelerate these discoveries and develop new treatments and cures.

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