Psoriasis is a long-term disorder where multiple parts of the body can become inflamed. It affects about 3% of the U.S. population. In this Massachusetts General Hospital Blum Center presentation from April 21, 2021, Flavia Fedeles, MD, gives an overview of the signs, symptoms and diagnosis of the different types of psoriasis. She also provides the latest guidelines for the management and treatment of psoriasis, including topical and systemic (biologic and non-biologic) medications.