The Center for Surgery, Innovation & Bioengineering

The Center for Surgery, Innovation & Bioengineering is a clinically-driven enterprise that engages in the basic sciences and engineering to improve health care delivery and further the use of personalized medicine, minimally invasive therapies and new technologies for today’s and tomorrow’s diagnostics and treatments. The center arises from Massachusetts General Hospital’s clinical research and is the vehicle to support the expansion of the overlapping expertise of three longstanding and successful research and innovation centers:

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The Center for Engineering in Medicine & Surgery

This center comprises the diversity of interests and skills involved in its activities. The focus is neither on a single disease nor on a single group of technologies. Instead, vitality springs from creating novel applications using the tools of disparate disciplines ranging from molecular biology and biochemistry to engineering design and analysis. These technologies are being applied to "thrust areas" in artificial organ development, biopreservation, metabolic engineering, stem cell bioengineering, genomics and proteomics, microfabrication and nanotechnology, drug delivery and tissue repair.

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The Mass General Burn Research Center

This center has devoted over three decades of research to improving the care of severely burned patients. Working together for many years, a unique combination of scientists and physicians are pushing the frontiers of knowledge about how the human body responds to burn injury. Through experiments using cutting-edge technologies, the program has yielded major clinical advances including new understanding of the critical role of nutrition in burn care, methods for immediate wound excision and closure in severely injured patients, and the development of artificial skin.

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The BioMEMS Resource Center

This center focuses to develop research efforts on bridging technological advances in microelectromechanical systems (MEMS), biomaterials and biochemical analysis, with biological research and clinical diagnostic and treatment needs. Biomedical applications of microfabricated devices are no longer limited to non-living systems as genes on a chip or labs on a chip. Today, a new generation of microdevices that incorporates living cells is emerging, fueled by recent advances in the understanding of cellular behavior in microenvironments. These emerging devices are expected to become key technologies in the 21st century of medicine, with a broad range of applications varying from diagnostic, tissue-engineered products, cell-based drug screening tools and basic molecular biology tools.

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