Search Cancer Clinical Trials

Mass General Cancer Center offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
18 results
  • Liver Cancer, Lung Cancer, Ovarian Cancer, Pancreatic Cancer, Sarcoma, Thyroid Cancer, Breast Cancer, Head and Neck Cancer, Kidney Cancer

23-301          Phase I

A First-in-Human, Open-label, Multicenter, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Participants with Advanced Solid Tumors

  • Gastric (Stomach) Cancer, Esophageal Cancer, Pancreatic Cancer

21-385          Phase I

A PHASE 1 STUDY OF TJ033721 IN SUBJECTS WITH ADVANCED OR METASTATIC SOLID TUMORS

  • Pancreatic Cancer, Lung Cancer, Melanoma, Colorectal Cancer

21-184          Phase I

A Phase 1, First-in-Human Study of DCC-3116 as a Single Agent and in Combination with Trametinib in Patients with Advanced or Metastatic Solid Tumors with RAS or RAF Mutations

  • Pancreatic Cancer, Lung Cancer, Colorectal Cancer

23-123          Phase II

A Phase 1/2 Multiple Expansion Cohort Trial of MRTX1133 in Patients with Advanced Solid Tumors Harboring a KRAS G12D Mutation

  • Pancreatic Cancer, Sarcoma, Bladder Cancer, Endometrial Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Liver Cancer

20-544          Phase II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation

  • Esophageal Cancer, Ovarian Cancer, Breast Cancer, Gastric (Stomach) Cancer, Head and Neck Cancer, Lung Cancer, Pancreatic Cancer, Colorectal Cancer, Melanoma

22-601          Phase II

A Phase 1/2, Open-Label, Single-Arm, Dose-Escalation and Dose-Expansion Study of the Safety, Tolerability, Pharmacokinetic, and Antitumor Activity of E-602 as a Single Agent and in Combination with Pembrolizumab in Patients with Advanced Cancers

  • Sarcoma, Prostate Cancer, Pancreatic Cancer, Lung Cancer, Kidney Cancer, Gastric (Stomach) Cancer, Endometrial Cancer, Colorectal Cancer, Cervical Cancer, Bladder Cancer, Breast Cancer

23-392          Phase I

A Phase 1a/1b, Dose-Escalation/Dose-Expansion study of NPX267 in Subjects with Solid Tumors Known to Express HHLA-2

  • Colorectal Cancer, Pancreatic Cancer, Gastric (Stomach) Cancer

22-129          Phase II

A Phase 1b/2 Study of Agents Targeting the Mitogen-Activated Protein Kinase Pathway in Patients with Advanced Gastrointestinal Malignancies (HERKULES-3)

  • Pancreatic Cancer

22-216          Phase II

A Phase 2 Study to Evaluate the Efficacy and Safety of Belzutifan (MK-6482, formerly PT2977) Monotherapy in Participants with Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), or von Hippel-Lindau (VHL) Disease-Associated Tumors

  • Pancreatic Cancer, Colorectal Cancer, Lung Cancer

20-671          Phase II

A Phase Ib/II Open-label, Multi-center Dose Escalation Study of JDQ443 in Patients with Advanced Solid Tumors Harboring the KRAS G12C Mutation

Showing 1 - 10 of 18 results