Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
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18 results
  • Liver Cancer, Lung Cancer, Gallbladder and Bile Duct Cancers, Gastric (Stomach) Cancer, Endometrial Cancer, Colorectal Cancer, Pancreatic Cancer

26-175          Phase I

A First-in-Human Phase 1 Dose-Escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation

  • Endometrial Cancer, Lung Cancer, Breast Cancer

25-439          Phase I

A First-in-Human, Phase 1a/1b Trial to Assess the Safety, Tolerability and Preliminary Efficacy of LY4175408, an Antibody Drug Conjugate Targeting Protein Tyrosine Kinase 7-Expressing Tumor Cells, in Participants with Selected Advanced Solid Tumors

  • Pancreatic Cancer, Lung Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Esophageal Cancer, Colorectal Cancer, Cervical Cancer, Bladder Cancer, Endometrial Cancer

25-816          Phase I

A Phase 1 Open-Label Study to Evaluate Safety, Pharmacokinetics, and Preliminary anti-Tumor Activity of STRO-004 in Adults with Refractory/Recurrent Metastatic Solid Tumors

  • Endometrial Cancer, Ovarian Cancer, Cervical Cancer, Breast Cancer

25-490          Phase I

A Phase 1, Open-Label Dose Escalation and Expansion Study of SNV4818 as Monotherapy or in Combination with other Anticancer Agents in Participants with Advanced Solid Tumors

  • Bladder Cancer, Pancreatic Cancer, Ovarian Cancer, Lung Cancer, Endometrial Cancer, Colorectal Cancer

25-783          Phase I

A Phase 1/1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of AMG 410 Alone and in Combination with other agents in Participants with KRAS Altered Advanced or Metastatic Solid Tumors

  • Endometrial Cancer, Gastric (Stomach) Cancer, Bladder Cancer, Sarcoma, Pancreatic Cancer, Esophageal Cancer, Liver Cancer

20-544          Phase II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation

  • Head and Neck Cancer, Lung Cancer, Ovarian Cancer, Endometrial Cancer, Esophageal Cancer

25-622          Phase II

A Phase 1/2 Trial of TER-2013 in Participants with Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

  • Lung Cancer, Ovarian Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Esophageal Cancer, Endometrial Cancer, Cervical Cancer, Breast Cancer

26-124          Phase I

A Phase 1a/1b Study of NRM-823 as Monotherapy and in Combination with Immune Checkpoint Inhibition in Participants with Locally Advanced or Metastatic Refractory Solid Tumors

  • Endometrial Cancer

18-301          Phase II

A Phase 2 Study of Abemaciclib in Combination with Letrozole or in Combination with Letrozole and Metformin in Recurrent or Persistent Endometrial Cancer

  • Endometrial Cancer, Melanoma, Pancreatic Cancer, Colorectal Cancer, Lung Cancer

26-098          Phase II

A Phase 2, Open-Label, Single-Arm Study of Lirafugratinib in Patients With Previously Treated, Unresectable, Locally Advanced or Metastatic Solid Tumors (Excluding Cholangiocarcinoma) With FGFR2 Fusion or Rearrangement

Showing 1 - 10 of 18 results