Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
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16 results
  • Colorectal Cancer, Endometrial Cancer, Gastric (Stomach) Cancer, Lung Cancer, Gallbladder and Bile Duct Cancers, Liver Cancer, Pancreatic Cancer

26-175          Phase I

A First-in-Human Phase 1 Dose-Escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation

  • Endometrial Cancer, Lung Cancer, Breast Cancer

25-439          Phase I

A First-in-Human, Phase 1a/1b Trial to Assess the Safety, Tolerability and Preliminary Efficacy of LY4175408, an Antibody Drug Conjugate Targeting Protein Tyrosine Kinase 7-Expressing Tumor Cells, in Participants with Selected Advanced Solid Tumors

  • Endometrial Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Esophageal Cancer, Pancreatic Cancer, Lung Cancer, Colorectal Cancer, Cervical Cancer, Bladder Cancer

25-816          Phase I

A Phase 1 Open-Label Study to Evaluate Safety, Pharmacokinetics, and Preliminary anti-Tumor Activity of STRO-004 in Adults with Refractory/Recurrent Metastatic Solid Tumors

  • Ovarian Cancer, Endometrial Cancer, Cervical Cancer, Breast Cancer

25-490          Phase I

A Phase 1, Open-Label Dose Escalation and Expansion Study of SNV4818 as Monotherapy or in Combination with other Anticancer Agents in Participants with Advanced Solid Tumors

  • Lung Cancer, Pancreatic Cancer, Ovarian Cancer, Bladder Cancer, Colorectal Cancer, Endometrial Cancer

25-783          Phase I

A Phase 1/1b Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of AMG 410 Alone and in Combination with other agents in Participants with KRAS Altered Advanced or Metastatic Solid Tumors

  • Pancreatic Cancer, Sarcoma, Liver Cancer, Bladder Cancer, Endometrial Cancer, Esophageal Cancer, Gastric (Stomach) Cancer

20-544          Phase II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation

  • Lung Cancer, Ovarian Cancer, Endometrial Cancer, Esophageal Cancer, Head and Neck Cancer

25-622          Phase II

A Phase 1/2 Trial of TER-2013 in Participants with Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

  • Cervical Cancer, Endometrial Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Head and Neck Cancer, Lung Cancer, Ovarian Cancer, Breast Cancer

26-124          Phase I

A Phase 1a/1b Study of NRM-823 as Monotherapy and in Combination with Immune Checkpoint Inhibition in Participants with Locally Advanced or Metastatic Refractory Solid Tumors

  • Endometrial Cancer

18-301          Phase II

A Phase 2 Study of Abemaciclib in Combination with Letrozole or in Combination with Letrozole and Metformin in Recurrent or Persistent Endometrial Cancer

  • Kidney Cancer, Breast Cancer, Endometrial Cancer, Pancreatic Cancer, Melanoma, Lung Cancer, Liver Cancer

25-587          Phase II

A Phase I/II, open-label, adaptive two-part trial to evaluate the safety, efficacy, optimal dose and pharmacokinetics of BNT326 as monotherapy and in combination with cancer immunotherapies in participants with advanced solid tumors

Showing 1 - 10 of 16 results