Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
16 results
  • Breast Cancer, Lung Cancer, Endometrial Cancer

25-439          Phase I

A First-in-Human, Phase 1a/1b Trial to Assess the Safety, Tolerability and Preliminary Efficacy of LY4175408, an Antibody Drug Conjugate Targeting Protein Tyrosine Kinase 7-Expressing Tumor Cells, in Participants with Selected Advanced Solid Tumors

  • Ovarian Cancer, Breast Cancer, Cervical Cancer, Endometrial Cancer

25-490          Phase I

A Phase 1, Open-Label Dose Escalation and Expansion Study of SNV4818 as Monotherapy or in Combination with other Anticancer Agents in Participants with Advanced Solid Tumors

  • Melanoma, Endometrial Cancer, Breast Cancer, Bladder Cancer, Ovarian Cancer, Uterine Cancer, Lung Cancer

22-430          Phase II

A Phase 1/2 First-in-Human Study of the Safety and Efficacy of IMC-F106C as a Single Agent and in Combination with Checkpoint Inhibitors in HLA-A*02:01-Positive Participants with Advanced PRAME-Positive Cancers

  • Pancreatic Cancer, Bladder Cancer, Endometrial Cancer, Esophageal Cancer, Sarcoma, Liver Cancer, Gastric (Stomach) Cancer

20-544          Phase II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation

  • Breast Cancer, Liver Cancer, Endometrial Cancer, Bladder Cancer

24-666          Phase II

A Phase 1/2 Study of a Selective FGFR2/3 Inhibitor, CGT4859, in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors Harboring FGFR2 and/or FGFR3 Genetic Alterations

  • Ovarian Cancer, Head and Neck Cancer, Esophageal Cancer, Endometrial Cancer, Lung Cancer

25-622          Phase II

A Phase 1/2 Trial of TER-2013 in Participants with Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

  • Endometrial Cancer

22-558          Phase II

A Phase 1/2a, Multicenter, Open-Label, Non-Randomized First in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1303 in Patients with Advanced/Metastatic Solid Tumors

  • Endometrial Cancer

18-301          Phase II

A Phase 2 Study of Abemaciclib in Combination with Letrozole or in Combination with Letrozole and Metformin in Recurrent or Persistent Endometrial Cancer

  • Liver Cancer, Kidney Cancer, Endometrial Cancer, Breast Cancer, Melanoma, Lung Cancer, Pancreatic Cancer

25-587          Phase II

A Phase I/II, open-label, adaptive two-part trial to evaluate the safety, efficacy, optimal dose and pharmacokinetics of BNT326 as monotherapy and in combination with cancer immunotherapies in participants with advanced solid tumors

  • Endometrial Cancer

25-361          Phase II

A PHASE II STUDY OF TAILORED ADJUVANT THERAPY IN POLE-MUTATED AND p53-WILDTYPE/NSMP EARLY STAGE ENDOMETRIAL CANCER (RAINBO BLUE & TAPER)

Showing 1 - 10 of 16 results