Search Cancer Clinical Trials

Mass General Cancer Center offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
16 results
  • Cervical Cancer, Ovarian Cancer, Lung Cancer, Head and Neck Cancer, Breast Cancer, Esophageal Cancer

22-281          Phase I

A Phase 1 Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of Second Mitochondrial-derived Activator of Caspases Mimetic BGB-24714 as Monotherapy and in Combination With Chemotherapy in Patients With Advanced or Metastatic Solid Tumors

  • Gastric (Stomach) Cancer, Esophageal Cancer, Pancreatic Cancer

21-385          Phase I

A PHASE 1 STUDY OF TJ033721 IN SUBJECTS WITH ADVANCED OR METASTATIC SOLID TUMORS

  • Prostate Cancer, Pancreatic Cancer, Ovarian Cancer, Lung Cancer, Head and Neck Cancer, Esophageal Cancer, Cervical Cancer, Breast Cancer, Bladder Cancer

24-114          Phase I

A Phase 1 Trial Investigating LY4101174, an Antibody-Drug Conjugate Targeting Nectin-4, in Participants with Recurrent, Advanced or Metastatic Solid Tumors

  • Endometrial Cancer, Bladder Cancer, Esophageal Cancer, Sarcoma, Gastric (Stomach) Cancer, Liver Cancer, Pancreatic Cancer

20-544          Phase II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation

  • Gastric (Stomach) Cancer, Lung Cancer, Ovarian Cancer, Bladder Cancer, Esophageal Cancer, Breast Cancer

23-679          Phase II

A Phase 1/2 Study of PRO1107 in Patients with Advanced Solid Tumors

  • Esophageal Cancer, Gastric (Stomach) Cancer

19-771          Phase II

A Phase 2 Study of Zolbetuximab (IMAB362) as Monotherapy or in Combination with mFOLFOX6 in Subjects with Metastatic or Locally Advanced Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma whose Tumors have High or Intermediate Claudin (CLDN) 18.2 Expression

  • Gastric (Stomach) Cancer, Esophageal Cancer

22-253          Phase II

A Phase 2 Trial to Evaluate the Safety and Efficacy of Domvanalimab (AB154) and Zimberelimab (AB122) -Based Treatment Combinations in Patients with Advanced Upper Gastrointestinal Tract Malignancies

  • Esophageal Cancer, Gastric (Stomach) Cancer

20-433          Phase II

A Phase 2a, Multicenter, Open-Label Study of DKN-01 in Combination with Tislelizumab +/-Chemotherapy as First- Line or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (Distinguish)

  • Lung Cancer, Thymoma, Rectal Cancer, Ovarian Cancer, Melanoma, Kidney Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Esophageal Cancer, Colorectal Cancer

23-423          Phase I

A Phase I, Open-label, Multi-center Study of KFA115 as a Single Agent and in Combination with Tislelizumab in Patients with Select Advanced Cancers

  • Lung Cancer, Kidney Cancer, Esophageal Cancer, Head and Neck Cancer

22-571          Phase I

A phase I/Ib, open-label, multi-center, study of QEQ278 in patients with advanced solid tumors

Showing 1 - 10 of 16 results