Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
10 results
  • Breast Cancer, Colorectal Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Liver Cancer, Ovarian Cancer, Pancreatic Cancer

25-747          Phase I

A Dose Escalation and Dose Optimization Phase 1a/1b Study to Evaluate Safety, Tolerability and Dosimetry of Radioligand Therapy with LY4337713 in Adults with FAP-Positive Solid Tumors (FiREBOLT)

  • Ovarian Cancer, Pancreatic Cancer, Sarcoma, Thyroid Cancer, Lung Cancer, Head and Neck Cancer, Breast Cancer, Liver Cancer, Kidney Cancer

23-301          Phase I

A First-in-Human, Open-label, Multicenter, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Participants with Advanced Solid Tumors

  • Liver Cancer

24-265          Phase I

A Multicenter, Open-label, First-in-Human Study of TYRA-200 in Advanced Intrahepatic Cholangiocarcinoma and Other Solid Tumors with Activating FGFR2 Gene Alterations (SURF-201)

  • Liver Cancer

25-145          Phase I

A Multicenter, Open-label, First-in-Human Study of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors with Activating FGF/FGFR pathway aberrations (SURF-431)

  • Endometrial Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Liver Cancer, Sarcoma, Bladder Cancer, Pancreatic Cancer

20-544          Phase II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation

  • Liver Cancer

24-700          Phase I

A Phase I Dose Escalation and Cohort Expansion Study of TSR-022, an Anti-TIM-3 Monoclonal Antibody, In Patients with Advanced Sold Tumors (AMBER)

  • Breast Cancer, Pancreatic Cancer, Melanoma, Lung Cancer, Liver Cancer, Kidney Cancer, Endometrial Cancer

25-587          Phase II

A Phase I/II, open-label, adaptive two-part trial to evaluate the safety, efficacy, optimal dose and pharmacokinetics of BNT326 as monotherapy and in combination with cancer immunotherapies in participants with advanced solid tumors

  • Gallbladder and Bile Duct Cancers, Liver Cancer

21-725          Phase I

A Phase Ia/Ib Study of the Combination of the FGFR inhibitor Pemigatinib and the EGFR inhibitor Afatinib in Advanced Refractory Advanced Solid Tumors

  • Ovarian Cancer, Liver Cancer, Lung Cancer, Melanoma, Cervical Cancer, Head and Neck Cancer

25-877          Phase II

A Phase II, Multicenter, Open-Label Trial of DB-1311 in combination with BNT327 or DB-1305 in Participants with Advanced/Metastatic Solid Tumors

  • Liver Cancer

21-286          Phase I

Phase IB Study of Atezolizumab and Bevacizumab with SBRT for Unresectable Hepatocellular Carcinoma

Showing 1 - 10 of 10 results