Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
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56 results
  • Pancreatic Cancer, Lung Cancer, Colorectal Cancer

25-110          Phase I

3263-001: A Phase 1/1b Multiple Cohort Trial of ALTA3263 in Patients With Advanced Solid Tumors With KRAS Mutations

  • Colorectal Cancer, Endometrial Cancer, Gastric (Stomach) Cancer, Liver Cancer, Pancreatic Cancer, Gallbladder and Bile Duct Cancers, Lung Cancer

26-175          Phase I

A First-in-Human Phase 1 Dose-Escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation

  • Lung Cancer, Leukemia, Colorectal Cancer, Melanoma, Pancreatic Cancer

26-113          Phase I

A First-in-human Study of RLY-8161 for Treatment of Advanced NRAS-Mutant Melanoma and Other Solid Tumors

  • Thyroid Cancer, Sarcoma, Breast Cancer, Head and Neck Cancer, Kidney Cancer, Liver Cancer, Lung Cancer, Ovarian Cancer, Pancreatic Cancer

23-301          Phase I

A First-in-Human, Open-label, Multicenter, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Participants with Advanced Solid Tumors

  • Lung Cancer, Endometrial Cancer, Breast Cancer

25-439          Phase I

A First-in-Human, Phase 1a/1b Trial to Assess the Safety, Tolerability and Preliminary Efficacy of LY4175408, an Antibody Drug Conjugate Targeting Protein Tyrosine Kinase 7-Expressing Tumor Cells, in Participants with Selected Advanced Solid Tumors

  • Head and Neck Cancer, Lung Cancer

24-148          Phase II

A Modular, Open-label, Phase I/II Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of EP0031 in Patients with Advanced RET-altered Malignancies

  • Head and Neck Cancer, Lung Cancer, Melanoma, Bladder Cancer

18-418          Phase III

A Multicenter, Open label, Phase III Extension Trial to Study the Long-term Safety and Efficacy in Participants with Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab Trial.

  • Colorectal Cancer, Gastric (Stomach) Cancer, Esophageal Cancer, Endometrial Cancer, Lung Cancer, Head and Neck Cancer, Cervical Cancer, Bladder Cancer, Pancreatic Cancer

25-816          Phase I

A Phase 1 Open-Label Study to Evaluate Safety, Pharmacokinetics, and Preliminary anti-Tumor Activity of STRO-004 in Adults with Refractory/Recurrent Metastatic Solid Tumors

  • Lung Cancer

23-568          Phase I

A phase 1 study evaluating the safety, tolerability, and efficacy of bl-b01d1 in subjects with metastatic or unresectable non-small cell lung cancer and other solid tumors

  • Prostate Cancer, Colorectal Cancer, Lung Cancer

25-695          Phase I

A Phase 1 Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

Showing 1 - 10 of 56 results