Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
28 results
  • Ovarian Cancer, Cellular Therapy

24-570          Phase I

A Phase 1a/1b Study of 27T51, an anti-MUC16 CAR T cell drug product administered alone or in combination for participants with recurrent or refractory epithelial ovarian, primary peritoneal, or fallopian tube cancer

  • Prostate Cancer, Pancreatic Cancer, Ovarian Cancer, Lung Cancer, Head and Neck Cancer, Esophageal Cancer, Cervical Cancer, Bladder Cancer, Breast Cancer

24-353          Phase I

A Phase 1a/1b Study of LY4052031, an Antibody-Drug Conjugate Targeting Nectin-4, in Participants with Advanced or Metastatic Urothelial Carcinoma or Other Solid Tumors

  • Ovarian Cancer, Hematology, Lung Cancer, Breast Cancer

19-642          Phase III

A Phase 3 Randomized Placebo-controlled Double-blind Study of Romiplostim for the Treatment of Chemotherapy-induced Thrombocytopenia in Patients Receiving Chemotherapy for Treatment of Non-small Cell Lung Cancer (NSCLC), Ovarian Cancer, or Breast Cancer

  • Ovarian Cancer

24-453          Phase I

A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Subjects with Advanced Solid Tumors

  • Thymoma, Ovarian Cancer, Melanoma, Lung Cancer, Kidney Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Rectal Cancer, Esophageal Cancer, Colorectal Cancer

23-423          Phase I

A Phase I, Open-label, Multi-center Study of KFA115 as a Single Agent and in Combination with Pembrolizumab in Patients with Select Advanced Cancers

  • Metastatic/Advanced Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Endometrial Cancer, Colorectal Cancer, Cervical Cancer, Breast Cancer, Ovarian Cancer

23-618          Phase I

A Study to Evaluate the Safety and Tolerability of the Covalent Phosphoinositide-3-Kinase (PI3K)-alpha Inhibitor, TOS-358, in Adult Subjects with Select Solid Tumors

  • Vulva Cancer, Uterine Cancer, Ovarian Cancer, Cervical Cancer, Breast Cancer

24-485          Phase I

AKTive-001: A Phase 1/1b Multiple Cohort Trial of ALTA2618 in Patients with Advanced Solid Tumors with AKT1 E17K Mutation

  • Ovarian Cancer

25-428          Phase II

An Adaptive Clinical Platform Trial to Evaluate the Safety and Efficacy of COM701 as Monotherapy or Combination Therapy as Maintenance Therapy in Participants with Relapsed Platinum Sensitive Ovarian Cancer (PSOC)

  • Colorectal Cancer, Pancreatic Cancer, Ovarian Cancer, Lung Cancer

23-242          Phase I

An Open-Label Phase 1 Dose-Escalation and Expansion Study Investigating the Safety, Pharmacokinetics, Pharmacodynamics, and Activity of PRTH-101 Alone or in Combination with Pembrolizumab in Adults with Locally Advanced or Metastatic Solid Tumors

  • Ovarian Cancer

25-192          Phase II

CATALINA-2: A Phase 2 Study Evaluating The Efficacy And Safety Of TORL-1-23 in Women with Advanced Platinum-Resistant Epithelial Ovarian Cancer (Including Primary Peritoneal and Fallopian Tube Cancers) Expressing Claudin 6

Showing 1 - 10 of 28 results