About Sareh Parangi, MD

Watch a video about my work

Dr. Parangi is a busy endocrine surgeon and Professor of Surgery at Harvard Medical School in Boston. She is Chair of Surgery at Newton Wellesley Hospital and Director of Diversity, Equity and Inclusion for the Department of Surgery at Massachusetts General Hospital. She is dedicated to personalized care of patients with thyroid disease, including thyroid cancer and hyperparathyroidism. She focuses her clinical efforts on endocrine surgery and applies her basic science knowledge and expertise to tumor progression in thyroid cancer. She is one of a handful of thyroid surgeons with expertise in molecular biology and has over 100 publications, many on thyroid cancer therapeutics and the latest in imaging and treatment of hyperparathyroidism  in premiere journals. She has been a council member for the most prestigious organization of endocrine surgeons in the US, The American Association of Endocrine Surgeons, and Chair of the Publications committee of The American Thyroid Association. She has won numerous awards for her research on understanding the role of the BRAF oncoprotein, why some patients with thyroid cancer do worse than others and how to help them. Her work in thyroid cancer details certain key genetic changes seen more frequently in those who do poorly, to help elucidate the role of these genetic changes in the aggressive behavior of those cancers.  This important research effort focuses on clarifying the molecular mechanism of thyroid cancer invasion and understanding the process of disease progression in patients with thyroid cancer.

Video: Preparing for Thyroid Surgery

VideoPlanning a Career in Academic Surgery

Charged Episode Featuring Dr. Parangi: Making Surgery a More Sustainable Career for Women

Clinical Interests:

Treats:

Locations

Newton-Wellesley Hospital
2014 Washington St.
Newton, MA 02462
For patient appointments: 617-243-6000

Massachusetts General Hospital
55 Fruit St.
Boston, MA 02114
For patient related matters: 617-831-7515

Medical Education

  • MD, Columbia University College of Physicians & Surgeons
  • Residency, University of California - San Francisco
  • Fellowship, University of California - San Francisco
  • Fellowship, Whitehead Institute

American Board Certifications

  • General Surgery, American Board of Surgery

Accepted Insurance Plans

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Research

Dr. Sareh Parangi has been one of the Boston surgeons named in Best Doctor and her excellence in both research and her clinical expertise have earned her a national reputation.  She is one of a handful of endocrine surgeons with expertise in molecular biology and has over 100 publications, many on thyroid cancer therapeutics as well as management of hyperparathyroidism in premier journal. She has taught about thyroid cancer care at the Harvard Course "Advances in Cancer Management for the Surgeon" and about thyroid and parathyroid ultrasound at the American College of Surgeons. 

Dr. Parangi has been able to balance her passion for translational research with innovative and compassionate care to patients with complex thyroid and parathyroid diseases.  Her work in thyroid cancer details certain key genetic changes seen more frequently in those who do poorly, to help elucidate the role of these genetic changes in the aggressive behavior of those cancers.  This important research effort focuses on clarifying the molecular mechanism of thyroid cancer invasion and understanding the process of disease progression in patients with thyroid cancer. Dr. Parangi's laboratory has started to characterize how a common genetic mutation in aggressive thyroid cancer BRAF (V600E) leads to thyroid cancer cell invasion, migration and metastasis. She has established the endocrine tumor tissue repository in 2008 and the molecular diagnostics laboratory is has been combined with other translational research efforts at the MGH including the Endocrine Surgery Clinical Database under the auspices of the Codman Center for Clinical Effectiveness and basic science laboratory research to improve translational research in thyroid cancer.

Publications

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