New research points to a promising strategy to boost tumors’ intake of cancer drugs, thereby increasing the effectiveness of chemotherapy treatments.
Sareh Parangi, MD
Sareh Parangi, MD
Chair of Surgery at Newton-Wellesley Hospital
Director MGH Thyroid Cancer Research Laboratory
Departments, Centers, & Programs:
Mass General Surgery
55 Fruit St.
Boston, MA 02114
For patient appointments: 617-724-2453
2014 Washington St.
Newton, MA 02462
For patient related matters: 617-243-6000
- MD, Columbia Univ College of Physicians & Surgeon
- Residency, University of California - San Francisco
- Fellowship, University of California - San Francisco
- Fellowship, Whitehead Institute
American Board Certifications
- General Surgery, American Board of Surgery
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Dr. Sareh Parangi has been one of the Boston surgeons named in Best Doctor and her excellence in both research and her clinical expertise have earned her a national reputation. She is one of a handful of endocrine surgeons with expertise in molecular biology and has over 100 publications, many on thyroid cancer therapeutics as well as management of hyperparathyroidism in premier journal. She has taught about thyroid cancer care at the Harvard Course "Advances in Cancer Management for the Surgeon" and about thyroid and parathyroid ultrasound at the American College of Surgeons.
Dr. Parangi has been able to balance her passion for translational research with innovative and compassionate care to patients with complex thyroid and parathyroid diseases. Her work in thyroid cancer details certain key genetic changes seen more frequently in those who do poorly, to help elucidate the role of these genetic changes in the aggressive behavior of those cancers. This important research effort focuses on clarifying the molecular mechanism of thyroid cancer invasion and understanding the process of disease progression in patients with thyroid cancer. Dr. Parangi's laboratory has started to characterize how a common genetic mutation in aggressive thyroid cancer BRAF (V600E) leads to thyroid cancer cell invasion, migration and metastasis. She has established the endocrine tumor tissue repository in 2008 and the molecular diagnostics laboratory is has been combined with other translational research efforts at the MGH including the Endocrine Surgery Clinical Database under the auspices of the Codman Center for Clinical Effectiveness and basic science laboratory research to improve translational research in thyroid cancer.
Related News and Articles
- Staff Story
- Mar | 5 | 2018
Sareh Parangi, MD, is a professor of surgery at Massachusetts General Hospital. She recently became the second ever female professor of surgery in the history of Mass General. She is also a president of the Association of Women Surgeons.
- Mar | 6 | 2019
Episode #21 of the Charged podcast