About Genevieve Boland, MD, PhD

Genevieve M. Boland, MD, PhD, FACS is an Associate Professor of Surgery at Harvard Medical School, Section Head of Melanoma/Sarcoma Surgery, and Surgical Director of the Termeer Center for Targeted Therapies at the Massachusetts General Hospital.  Her primary clinical focus is on melanoma and cutaneous oncology.

She undertook combined MD/PhD training, completing a PhD in Cell and Tissue Engineering at the National Institutes of Health focusing on signaling pathways in adult, human mesenchymal stem cells. She graduated cum laude from Thomas Jefferson University as a member of the Alpha Omega Alpha medical honor society and completed her general surgical training at Massachusetts General Hospital. Following this, she completed a clinical fellowship in Complex General Surgical Oncology and a combined research fellowship at the University of Texas MD Anderson Cancer Center. She is focused on the clinical management of skin cancer patients. She is board certified in General Surgery and Complex General Surgical Oncology, and she is a Fellow of the American College of Surgeons.

Dr. Boland has received research support from many groups including the American Surgical Association Foundation Fellowship, the Association of Women Surgeons Research Fellowship, the Harvard Catalyst Medical Research Investigator Training Award, the Karin Grunebaum Cancer Foundation Fellowship, the Society of Surgical Oncology, the Melanoma Research Foundation Breakthrough Consortium, the National Institutes of Health, and the Department of Defense. She is Director of the Surgical Oncology Research Laboratories and Director of the Therapeutic Intralesional Program where she is building a portfolio of direct-to-tumor therapies across multiple tumor types. She is also an Associate Member of the Broad Institute of MIT and Harvard. Her laboratory is currently focused on molecular profiling of melanoma, characterization of molecular and immunological changes that occur during immunotherapy, and the identification of circulating biomarkers of cancer.

Clinical Interests:



Mass General Surgery: Surgical Oncology
55 Fruit St.
Yawkey Center for Outpatient Care
7th Floor
Boston, MA 02114
Phone: 617-724-4000

Mass General Brigham Healthcare Center
52 Second Ave.
Waltham, MA 02451
Phone: 617-724-4400

Medical Education

  • MDPhD, Thomas Jefferson University
  • Residency, Massachusetts General Hospital
  • Fellowship, M.D. Anderson Cancer Center

American Board Certifications

  • Complex General Surgical Oncology, American Board of Surgery

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Dr. Boland's research focuses on questions relating to melanoma genetics, biology, and immunology using genomic, transcriptomic, and proteomic approaches to profiling patient-derived samples.

Current Research Interests:

  1. Identification of circulating biomarkers of cancer and integration into the clinical management of cancer patients.
  2. Analysis of treatment-related effects on the tumor and microenvironment, including changes occurring during treatment with immunotherapy.
  3. Tumor heterogeneity and tumor evolution.
  4. The combined use of surgery and systemic therapy for treatment of high risk melanoma patients.
  5. Neoadjuvant and adjuvant approaches via direct-to-tumor therapies.


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