Clinical trials are scientific studies in which new treatments are tested in patients to determine if they are effective and safe.

The Department of Radiation Oncology's clinical trials offer access to promising new therapies. Browse our clinical trials below, and click on the trial name for more information.

Brain/CNS tumors

  • Pilot Study of In-Room PET in Proton Radiation Therapy
    • This trial evaluates the use of a type of radiological imaging called PET to take pictures of a patient’s tumor immediately after they receive a treatment with proton radiation therapy.
    • Principal Investigator: Helen Shih, MD
    • DFCI #10-241

Brain tumors

Breast

Colorectal

Colorectal cancer spread to the liver

Liver

Low/intermediate grade glioma

Meningioma

Nasopharyngeal

Neuroblastoma

Non-small cell lung cancer

Oropharyngeal

  • NCI: IMPT or IMRT in Oropharyngeal cancer of head and neck
    • The goal of this study is to evaluate two different radiation techniques (intensity-modulated proton therapy-IMPT or intensity-modulated photon therapy-IMRT) for the treatment of head and neck cancer. All patients will receive chemotherapy along with radiation therapy.
    • Principal Investigator: Paul Busse, MD, PhD
    • DFCI #16-155

Pancreatic

Pediatric brain/CNS tumors

Pediatric cancers

Prostate

Retroperitoneal sarcoma

Rhabdomyosarcoma

Sinonasal

  • Proton vs. IMRT for Sinonasal Malignancies
    • The purpose of this study is to evaluate two different radiation techniques (intensity-modulated proton therapy-IMPT or intensity-modulated photon therapy- IMRT) for sinonasal cancers.
    • Principal Investigator: Annie Chan, MD
    • DFCI #10-308

Vestibular schwannoma