Lurie Center for Autism Clinical Research

The mission of the Lurie Center for Autism is to advance knowledge of the causes of and treatments for autism spectrum disorder and other developmental disorders and rapidly translate these discoveries into exceptional clinical care over a lifetime.

The Lurie Center for Autism is involved in collaborations with basic science researchers from around the globe to discover the fundamental causes of autism. At the Lurie Center, our Lexington based clinic that provides clinical care and clinical research, we offer children and adults with autism spectrum disorder an opportunity to participate in clinical research that provides unprecedented access to new and promising treatment options.

At the Lurie Center, we integrate research into our clinical practice. We partner with individuals and families to incorporate groundbreaking research into the heart of our clinical practice. With participation in research, our study volunteers join an important partnership with the research community and contribute to increasing knowledge of autism and related disorders.

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Current Lurie Center for Autism studies for Children:

• Genome Environment Microbiome and Metabolome in Autism (GEMMA) (pdf)
  To learn more about the GEMMA study, follow this link.
• Long-term Antipsychotic Pediatric Safety Trial (LAPS) (pdf)
• ATN Autism Learning Health Network (ALHN) (pdf)
• Axial Study - Evaluating the efficacy, safety, and tolerability of AB-2004 for improving irritability in adolescents who have been diagnosed with autism spectrum disorder and gastrointestinal symptoms.
  • Learn more about the Tapestry Study from this article published August 2022, in Autism Advocate Parenting Magazine.
• GW19189 (CBD) Study- Evaluating the safety and effectiveness of an investigational medication, a cannabidiol oral solution (GWP42003-P; CBD-OS), for improving behavior, social communication, and overall symptom severity in children and adolescents with an autism spectrum disorder.
• Precidag Study - Investigating the role of gut bacteria in children with autism spectrum disorder (ASD).
• POP02 Study - A study to learn more about medicines commonly used in children.
• Effect of Childhood ADHD on Substance Use and Related Disorders in Adolescents and Adults with ASD - click here for more details
• Characterizing sleep physiology in ASD: a path from genes to treatment. 
  
  • Individuals with ASD
  • Control Group

Current Lurie Center for Autism studies for Adults:

• Effect of Childhood ADHD on Substance Use and Related Disorders in Adolescents and Adults with ASD - click here for more details
• Investigation of Neuroinflammation in Autism Using MR-PET
  • Individuals with an ASD (pdf)
  • Control group (pdf)

• Neuroimaging HDAC
  • Individuals with an ASD (pdf)
  • Control group (pdf)
• Uncovering Communication Potential in Minimally Verbal Autism Spectrum Disorder
• IRIS – A randomized, double-blind, parallel group, placebo-controlled study to investigate the efficacy, safety, and tolerability of ML-004 in adolescents and adults with autism spectrum disorders (ASD). 
• Fluoxetine treatment of depression in adults with Down Syndrome
• Buspirone treatment for anxiety in individuals with Williams Syndrome

Clinical Research Participation

For more information about clinical research participation, visit the following links:

• National Institutes of Health (NIH) Kids in Research
• NIH Clinical Research Trials Basics
• Autism Speaks® Participant's Guide to Autism Drug Research