About Joseph Misdraji, MD

After receiving his medical training at the University of Miami School of Medicine, Dr. Misdraji completed his anatomic and clinical pathology training at the Massachusetts General Hospital where he also trained in cytopathology.  He is Director of the Gastrointestinal Pathology Unit in the Department of Pathology. His primary clinical interests are gastrointestinal and hepatic diseases, and cytopathology. Dr. Misdraji's research interests are focused on liver pathology, gastrointestinal diseases, and appendiceal neoplasia. He has an active consultative practice that is primarily composed of liver pathology and gastrointestinal pathology. He is co-director of the Harvard Medical School CME Course, Gastrointestinal, Liver and Pancreatic Pathology.

Departments, Centers, & Programs:

Clinical Interests:




Pathology Associates
55 Fruit Street
Boston, MA 02114-2696
Phone: 617-724-1577
Fax: 617-726-7474

Medical Education

  • MD, University of Miami School of Medicine
  • Residency, Massachusetts General Hospital
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Cytopathology, American Board of Pathology
  • Anatomic Pathology & Clinical Pathology, American Board of Pathology

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Research Interests include appendiceal neoplasms, hepatic diseases and gastrointestinal diseases. Dr. Misdraji has published over 65 research papers. For more information about research concepts, co-authors, and to see a timeline, visit Dr. Misdraji's profile at the Harvard Clinical and Translational Science Center.


  • View my most recent publications at PubMed

      1. Misdraji J, Lauwers GY, Irving JA, Batts KP, Young RH. Appendiceal or cecal endometriosis with intestinal metaplasia: A potential mimic of appendiceal mucinous neoplasms. Am J Surg Pathol 2014;38:698-705.
      2. Hagen C, Kamionek M, McKinsey D, Misdraji J. Syphilis presenting as inflammatory tumors of the liver in HIV-positive homosexual men. Am J Surg Pathol 2014;38:1636-43.
      3. Arnason T, Kamionek M, Yang M, Yantiss RK, Misdraji J. Significance of proximal margin involvement in low grade appendiceal mucinous neoplasm. Arch Pathol Lab Med 2015;139:518-521.
      4. Johncilla M, Misdraji J, Pratt DS, Agoston AT, Lauwers GY, Srivastava A, Doyle LA. Ipilimumab-associated hepatitis: clinicopathologic characterization in a series of eleven cases. Am J Surg Pathol 2015;39:1075-1084.
      5. Shih AR, Lauwers, GY, Kamionek M, Mattia A, Schaefer EAK, Misdraji J. Vascular injury characterizes doxycycline-induced upper gastrointestinal tract mucosal injury. Am J Surg Pathol 2017;41:374-381.
      6. Hoda RS, Sanyal S, Abraham JL, Everett JM, Hundemer GL, Yee E, Lauwers GY, Tolkoff-Rubin N, Misdraji J. Lanthanum deposition from oral lanthanum carbonate in the upper gastrointestinal tract. Histopathology 2017;70:1072-1078.