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MassGeneral Hospital for Children
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Dr. Whalen's laboratory investigates causes and treatments for acute brain injury in children with mouse models and molecular and cell biology. The laboratory studies mechanisms of concussion, brain contusion, and intracerebral hemorrhage (a type of stroke) in pediatric and adult models. We focus on how inflammation drives neurological outcome in these models in order to discover new treatments to improve neurological outcome in children and adults with brain injury.
View my most recent publications at PubMed
Severe traumatic brain injury (TBI) is the leading cause of death and disability in children. Currently, therapy for childhood TBI is focused on controlling intracranial hypertension and minimizing secondary brain injury that may occur with hypotension, hypoxemia, seizures, fever, and other physiological insults.
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