Explore This Fellowship

The fellowship program in Pediatric Gastroenterology and Nutrition trains pediatricians to become experts in pediatric gastroenterology, hepatology and nutrition and to become independent basic scientists or clinical investigators.

Program Overview

The Pediatric Gastroenterology & Nutrition Division at MassGeneral Hospital for Children is a large, broad-based consultative service providing expertise in gastrointestinal, liver, pancreatic and nutritional disorders in infants, children and adolescents. Massachusetts General Hospital is a world leader in research and treatment of liver and gastrointestinal disorders and offers close collaboration between the pediatric and adult programs for patient care, and joint efforts in clinical and basic science research.

Clinical training during the 1st year of fellowship is divided into the following:

  • Inpatient service training: Our 1st year fellows split the daytime service weeks for the year. They are paired with an inpatient GI service attending for the week. They provide a primary service for children with a variety of GI conditions including inflammatory bowel disease. (Our IBD patient population is among the largest in the country.) They also care for children with liver disease and are paired with a primary liver service attending.
  • Endoscopy training: Our 1st year fellows are exposed to a wide range of endoscopic and advanced procedures including upper endoscopy, colonoscopy, pH/impedance probe placement, wireless pH probe deployment, colonoscopic polypectomy, esophageal manometry, and anorectal manometry with rectal suction biopsy and botulinum toxin injection. Each 1st year fellow completes >300 procedures which is one of the highest numbers across the country.
  • Continuity clinic: Our fellows have weekly continuity clinic where patients are assigned directly to them. A purposeful balance between common GI problems and complex care are seen.
  • Liver transplant clinic: The first year fellow regularly attends our multidisciplinary liver transplant clinic that regularly sees patients with end-stage liver disease during the transplant evaluation process as well as cares for those patients who are post-transplant
  • Multi-disciplinary subspecialty clinics: Our fellows are strongly encouraged to rotate through our multi-disciplinary clinics that include Celiac disease clinic, Feeding Team clinic, Neurogastroenterology clinic, and Inflammatory bowel disease clinic.

A number of centers of excellence exist within the Pediatric Gastroenterology & Nutrition Division at MassGeneral Hospital for Children, including:

  • Center for Celiac Research & Treatment is dedicated to improving the quality of life for patients with celiac disease, while learning the cause of the disease and finding a cure.
  • Center for Diagnostic, Therapeutic and Interventional Endoscopy provides both diagnostic and interventional procedures in a state-of-the-art pediatric endoscopy unit.
  • Center for Nutrition focuses on a multidisciplinary approach to treat children with nutritional issues, in particular feeding difficulties and overweight or obesity. The programs integrate state-of-the-art resources with compassionate and comprehensive care.
  • Center for Inflammatory Bowel Disease provides multidisciplinary clinical care for the most challenging pediatric patients with inflammatory bowel disease. Through population studies, the center is engaged in clinical, translational and basic science studies in the immunological and the genetic basis of the disease.
  • Food Allergy Center provides unified multidisciplinary consultation among specialists in Pediatric Gastroenterology, Pulmonary, Psychology, as well as adult and pediatric allergists. This multispecialty collaboration facilitates outstanding clinical and basic science research opportunities.
  • Liver Transplantation an integral part of the Mass General Transplant Program, it provides coordinated, multidisciplinary long-term care to pediatric patients before and after organ transplantation.
  • Neurogastroenterology Program provides a multidisciplinary team approach aimed at restoring nutritional status and improving bowel function in children with a variety of congenital or acquired intestinal problems
  • Airway, Voice and Swallowing Center for Children combines the expertise of multiple medical sub-specialties, including Pediatric Otolaryngology, Gastroenterology and Pulmonology in the coordinated assessment and management of children with disorders involving the airway and swallowing.
  • Center for Pediatric Hepatobiliary and Pancreatic Disease provides clinical care for infants and children with liver disease and supports a very active teaching and research effort.
  • Lurie Center for Autism is a multidisciplinary program designed to evaluate and treat children, adolescents and adults with a wide variety of conditions including autism and autism spectrum disorders, Asperger syndrome and developmental delays. It is the clinical arm of the Lurie Center for Autism, which also has research, advocacy and training programs.
  • Pediatric Weight Center provides advanced, comprehensive, multidisciplinary care for both children and adults. Also an NIH funded, clinical and basic research center.

The overall goals and objectives of the fellowship program in Pediatric Gastroenterology & Nutrition are to fully train pediatricians to become expert, board certified consultants in Pediatric Gastroenterology, Hepatology and Nutrition in an academic setting and to have the capacity to become independent basic scientists or clinical investigators.

The clinical training entails developing competency in all procedures, including investigative and interventional endoscopy, pH and impedance probe use and interpretation, and the performance and interpretation of motility studies. At the completion of their training, fellows must have a comprehensive knowledge of the field and have the ability to present data in an oral and written manner and have a complete understanding of the scientific method.

Research Experience

First-year fellows are exposed to a wide variety of potential research experiences through personal interactions with the pediatric GI faculty as well as faculty throughout the Mass General and Harvard Medical School system during conferences and other opportunities.

First-year fellows meet with the program director to discuss their interests in clinical/basic science research and meet with investigators within the division as well as throughout the institution to help formulate plans for a research experience during their second and third years of fellowship. When a fellow decides on a research project and a research mentor, a scholastic oversight committee (SOC) is formed to oversee the research project and the progress achieved. The chairperson of the SOC is the pediatric GI faculty advisor for the fellow and is responsible for compiling a summary report of each SOC meeting, held twice yearly, that is submitted to the program director.

Additionally, fellows are strongly encouraged to supplement their experience with formal courses (basic science, statistics, study design and methodologies) at Mass General, Harvard and MIT. For those research fellows desiring an extended in-depth research experience, additional protected time (minimum of 50%) as a junior faculty member is encouraged through application for various career awards such as Clinical Investigator Award (CIA) or the Physician Scientist Award (PSA) at the National Institutes of Health. The goal of this comprehensive program is to train an independent Pediatric Gastroenterology & Nutrition consultant capable of achieving independent grant-supported funding with either clinical or basic research interests for a faculty position at a medical school in the United States or elsewhere.

Although multiple research opportunities are available to fellows within the division of pediatric gastroenterology and the Mucosal Immunology Laboratory, each fellow is encouraged to explore other research opportunities within Harvard University and MIT.

Research Opportunities

  • Goldstein Laboratory- My laboratory is interested in the development of the enteric nervous system (ENS), a complex neuronal network whose principal function is to maintain normal intestinal motility.
  • Harvard Catalyst- Harvard Catalyst brings together the intellectual force, technologies, and clinical expertise of Harvard University and its affiliates and partners to reduce the burden of human illness.
  • The Laboratory for Tissue Engineering and Organ Fabrication- The Laboratory for Tissue Engineering and Organ Fabrication is designing and building replacement living tissues and organs to ultimately translate to clinical therapies.
  • Lurie Center for Autism Research- The mission of the Lurie Center for Autism is to advance knowledge of the causes of and treatments for autism spectrum disorders and other developmental disorders and rapidly translate these discoveries into exceptional clinical care over a lifetime.
  • Mucosal Immunology and Biology Research Center- The major mission of the Mucosal Immunology and Developmental Gastroenterology Laboratories remains a multidisciplinary approach to characterize the role of the enterocyte in mucosal barrier function at the interface between microbial luminal stimuli and lymphoid effector responses.
  • Pediatric Liver and Biliary Disease Center- The Pediatric Hepatobiliary & Pancreatic Program at MassGeneral Hospital for Children diagnoses and treats infants, children and adolescents with diverse hepatic, biliary and pancreatic disorders.
  • Pediatric Inflammatory Bowel Disease Center – The Pediatric IBD center at MGHfc studies the microbiome and genetic drivers of disease through a number of collaborations within Boston and beyond.
  • Adolescent and Pediatric Weight Center- The pediatric weight program at the Massachusetts General Hospital Weight Center provides comprehensive evaluation and care for children and adolescents who are overweight or obese.
  • Shreffler Laboratory- The Shreffler Laboratory is interested in the mechanisms regulating both primary sensitization and the subsequent balance between immune progression or regulation that determines either clinical sensitivity or tolerance to mucosal allergens.

History of Pediatric Gastroenterology & Nutrition at MassGeneral Hospital for Children

The Pediatric Gastroenterology Unit of what was known as the Children’s Service at Massachusetts General Hospital was established in 1972. The unit’s first director, Allan Walker, MD, trained in Pediatrics and Immunology at the University of Minnesota Hospitals under Robert Good, MD. Since no pediatric gastroenterology (GI) training programs existed in 1969, Dr. Walker left pediatrics for three years to train as an adult GI fellow with Dr. Kurt Isselbacher on the Medical Service at Mass General.

Once established, the nascent Pediatric GI Unit received substantial impetus by aligning itself with the well-established and nationally recognized GI Unit of the Medical Services at Mass General. Pediatric GI fellows could take rotations in medical GI, attend and participate in weekly GI Grand Rounds and journal clubs as well as the weekly research conference. Since Pediatric GI had no NIH training grant at its beginning, Dr. Isselbacher graciously allowed the Pediatric GI fellows to be funded on his training grant during their two year period of research fellowship.

This close working relationship with Adult GI has continued to be a major strength of the Pediatric GI program at MassGeneral Hospital for Children and has led to many collaborations in both basic and clinical research over the years, most recently with the support of Dr. Daniel Podolsky, who followed Dr. Isselbacher as Chief of the GI Unit at Mass General and Dr. Ramnik Xavier, who has followed Dr. Podolsky. Since GI subspecialty patients frequently require ongoing care beyond the cut off period of 21 years for pediatrics, it is helpful to have transitional care by both pediatric and medical gastroenterologists until the patient adjusts to a new situation. This is done seamlessly and provides outstanding continuity of patient care at Mass General.

Over the next 10 years after its inception, the pediatric unit flourished. Pediatricians in training became aware of the potential of gastroenterology as a subspecialty and Pediatric Department chairmen recognized the expanding field required more expertise than that provided by the General Academic Pediatrician. In addition, specialized procedures (liver biopsy, endoscopy, pH probes, etc.) became part of the practice of gastroenterology and could only be done by specially trained pediatric gastroenterologists. With the recognition that many gastrointestinal and hepatic conditions occurred in the pediatric age period and were more complex than conditions encountered in adult GI medicine, many pediatricians, interested in the pathophysiology of disease, were attracted to choose pediatric gastroenterology as a subspecialty.

Accordingly, the Pediatric GI Unit at Mass General, because of the reputation of gastroenterology at the hospital and because of the emphasis on a physician/scientist approach to the subspecialty, attracted outstanding applicants wishing to enter the field as academic subspecialists.

Beginning in 1972, two pediatricians from various training programs in the United States and elsewhere were accepted into the program. These trainees entered a three-year training program consisting of one year of clinical rotations in Pediatric Gastroenterology followed by two years of laboratory research in an established laboratory of investigation that could enhance the fellows’ research expertise in related areas of interest. From the beginning, the overall theme of research under Dr. Walker’s supervision was developmental mucosal immunology, work that continues to this day.

In 1981, with the departure of Richard Grand, MD, from Children’s Hospital to direct Pediatric GI at Tufts New England Medical Center/Floating Children’s Hospital, Dr. Walker was asked by Mary Ellen Avery, MD, Chairman of Pediatrics at Children’s Hospital, and Donald Medearis, MD, Chairman of the Children’s Service at Mass General, to establish a Combined Program in Pediatric Gastroenterology at the two pediatric services at Harvard.

From 1981 until 2001, a Combined Program in Pediatric Gastroenterology existed. In this program, four to five fellows per year were accepted for a three-year period of clinical and research training.

In 1990, the first Pediatric Gastroenterology subspecialty board examination was held to certify pediatric gastroenterologists as boarded subspecialists. This required three years of clinical and research training, which included a continuity clinic to follow patients during the two research years. A committee of faculty (within and outside of Pediatric GI) was established to monitor the progress of the fellows during their research experience.

During the early 1990’s, Harvard established a Clinical Effectiveness Program as a partnership between its hospitals and the Harvard School of Public Health to train fellows of various subspecialties in clinical research. This program occurred in parallel within the two years of fellowship by clinically-oriented fellows and could result, if the fellow so desired and took subsequent classes, in a Masters of Science Degree from the Harvard School of Public Health. This program expanded the options for GI fellows and in some cases junior faculty to do either bench or clinical research as part of their fellowship.

The years of combined fellowship in Pediatric GI at Harvard allowed for an expanded faculty development. Ronald Kleinman, MD, one of Dr. Walker’s earliest fellows, became the Division Chief of the program at Mass General. A major renovation of the joint endoscopy suite allowed for expanded procedural options in both pediatric and adult gastroenterology. In addition, an active Liver Transplant Service was added, which broadened the Pediatric GI referral base. Mass General combined with the Brigham and Women’s Hospital to form Partner’s Health Care, which increased the referral base for pediatric patients, thus expanding the Pediatric GI services.

In 2001, Dr. Walker stepped down from his role as Chief of the Combined Program in Pediatric Gastroenterology to return to Mass General to expand the research facilities. He obtained 15,000 square feet of research space and expanded the Pediatric GI capacity to include eight Principal Investigators, 15 research fellows, (including two Pediatric GI fellows doing basic research) and several graduate students in Building 149 and Building 114 in the Charlestown Navy Yard (an expanded off campus research facility for Mass General).

From its inception as a Pediatric Unit to the establishment of a combined program and then two separate programs again in Pediatric GI (occurring in 2005), more than 100 Pediatric GI fellows have been trained in the Mass General program. Many of these fellows have established their own program in Pediatric Gastroenterology at medical schools throughout the United States, the UK, Europe, Australia and Asia. Almost 50 percent of trainees are still actively involved in clinical or basic research and more than 80 percent practice at academic centers.

Program Accreditation

The Harvard Medical School Program in Pediatric Gastroenterology & Nutrition at MassGeneral Hospital for Children was accredited by the Accreditation Council for Graduate Medical Education (ACGME) as an independent program in July 2006. The program provides three years of progressive educational experience, which includes the development of procedural skills, responsibility for patient care, and participation in research that meets the program requirements of the ACGME and board eligibility in pediatric gastroenterology by the ABP for trainees completing the program.

Fellowship Curriculum

The Division of Pediatric GI and Nutrition meets weekly for an educational conference. The topic for that meeting is either:

  • Disease-based conference led by members of one of the Centers of Excellence at MGHfC providing key clinical and research updates in a particular disease process
  • Quality improvement conference led by our Quality and Safety team on either a division-wide effort (including initiatives from ImproveCareNow)
  • Quality improvement conference led by 2 of our pediatric GI fellows on their longitudinal quality improvement project
  • Clinical conference led by 1-2 pediatric GI fellows to discuss a challenging clinical case

The fellows leading these conferences have faculty mentoring them for these specific conferences to help develop their presentation style and content.

The weekly Pediatric GI Fellow Lecture series provides an opportunity for fellows to learn fundamental normal and pathologic physiology as well as standard of care practices in pediatric gastroenterology and nutrition. The topics of the lecture series are considered in a two year cycle, with some lectures presented every year and some learning objectives addressed every two years. The topics of the lecture series are based on a combination of the annual review of the Program Evaluation Committee as well as specific requests by the fellows.

All fellows and faculty are strongly encouraged to attend and participate in the weekly Pediatric Grand Rounds, Adult GI Grand Rounds and the Pediatric Anesthesia/Surgery Conference.

Teaching Opportunities

Fellows have active teaching roles with residents and medical students during inpatient rounds. Fellows may also choose to participate in formal resident education by being a lecturer on a selected topic for the resident noon conference or in a less formal way by participating in discussions during the daily resident morning report.

Affiliated Programs

Leadership

Dr. Christopher Moran is the Program Director of the Pediatric Gastroenterology Fellowship. He has been a life-long resident of Massachusetts, completing his undergraduate work at Boston College and his medical school training at Tufts University. After completing residency at MassGeneral Hospital for Children, he began his Pediatric GI fellowship at MGHfC and focused his research on studying inflammatory bowel disease (IBD). His current research is focused on the genetics of very early onset IBD (VEO-IBD) and histologic and radiologic biomarkers for IBD severity. He and his wife spend their free time with their two young children, teaching them about the folklore of the Boston Red Sox.

Dr. Kriston Ganguli left her home state of Minnesota to pursue her pediatric residency training in Boston. She was interested in pursuing fellowship training and was equally attracted to a career in pediatric gastroenterology and neonatology. She ultimately completed her fellowship training in pediatric gastroenterology at MassGeneral Hospital for Children, during which her research interest was founded. She was fortunate to join the MGHfC staff and currently balances clinical responsibilities with her basic science research career, investigating the use of secreted bacterial anti-inflammatory factors in reducing intestinal inflammation in preterm infants. Additionally, Dr. Ganguli is an Associate Director of the pediatric gastroenterology fellowship training program, Director of the MGHfC pediatric gastroenterology resident elective and the Physician Champion of the Quality Improvement Team within the division. Outside of her professional activities, she spends busy evenings and weekends with her husband and three active sons.

Dr. Gary Russell completed his pediatric residency and gastroenterology fellowship training at Riley Children’s Hospital, Indiana University. He moved to Boston to pursue research in the burgeoning field of mucosal immunology. His academic interests include inflammatory bowel disease, eosinophilic esophagitis and medical education. Dr. Russell was the program director of the HMS Program in Pediatric Gastroenterology and Nutrition at MGHfC from 2008-2020 and takes seriously his responsibility in helping guide the careers of the next generation of pediatric gastroenterologists.

How to Apply

We accept the common application available through ERAS online and are a participating program in the National Residency Matching Program. Interviews for selected applicants are held on Thursdays from September through November.

Our fellowship program accepts applicants with U.S. citizenship or ECFMG certified J1 visas without bias towards visa status. There must be a minimum of 3 three years remaining on the applicant’s visa in order to complete fellowship training. Our institutional Graduate Medical Education and ACGME accreditation requirements specify that all applicants must be board eligible/certified in pediatrics as determined by the American Board of Pediatrics.

Requirements

Our fellowship program accepts applicants with U.S. citizenship or ECFMG certified J1 visas without bias towards visa status. There must be a minimum of three years remaining on the applicant’s visa in order to complete fellowship training. Our institutional Graduate Medical Education and ACGME accreditation requirements specify that all applicants must be board eligible/certified in pediatrics as determined by the American Board of Pediatrics.

Our Fellows

First Year Fellows

Micaela Atkins, MD
Medical School: University of Massachusetts
Residency: MassGeneral Hospital for Children
Current Research Interests: TBD
Research Mentor: TBD
SOC Chairperson / Advisor: TBD

Tracey DaFonte, MD
Medical School: Robert Larner, M.D., College of Medicine at the University of Vermont
Residency: University of Massachusetts
Current Research Interests: TIBD
Research Mentor: TBD
SOC Chairperson / Advisor: TBD

Second Year Fellows

Awab Ali Ibrahim, MD
Medical School: Weill Cornell Medical College in Qatar
Residency: University of South Alabama
Current Research Interests: TBD
Research Mentor: Alessio Fasano, MD
SOC Chairperson / Advisor: TBD

Kayla Hartjes, MD
Medical School: University of Massachusetts Medical School
Residency: University of Massachusetts
Current Research Interests: The use of ultrasound in studying clinical course of non-alcoholic fatty liver disease
Research Mentor: Tracey Simon, MD and Raymond Chung, MD
SOC Chairperson / Advisor: TBD

Third Year Fellows

Katherine Olshan, MD
Medical School: Medical College of Wisconsin
Residency: University of Massachusetts
Current Research Interests: Role of breastmilk composition on the development of celiac disease in at risk infants.
Research Mentor: Maureen Leonard, MD, MMSc, and Alessio Fasano, MD
SOC Chairperson / Advisor: Navneet Virk Hundal, MD

Desiree Sierra Velez, MD
Medical School: University of Puerto Rico Medical School
Residency: Nicklaus Children's Hospital
Current Research Interests: Evidence-based interventions for management of pediatric obesity.
Research Mentor: Lauren Fiechtner, MD, MPH and Elsie Taveras, MD, MPH
SOC Chairperson / Advisor: Harland Winter, MD

Contact

MGHfC Pediatric Gastroenterology & Nutrition Fellowship

  • Phone: 617-724-2561
  • Fax: 617-724-2710

Program Coordinator
Cate Kron
Phone: 617-726-1450
Fax: 617-724-2710
ckron@mgh.harvard.edu

Program Manager/Visa Manager
Erin O’Reilly
Phone: 617-643-9730
eoreilly@mgh.harvard.edu

Program Director
Christopher Moran, MD
Phone: 617-726-1450
Fax: 617-724-2710
cjmoran@mgh.harvard.edu

Recent Graduates

Corey Baker, MD
Current Position: Director of Neurogastroenterology, Connecticut Children’s Hospital
Research while at MGHfC: To Develop a model to study murine gastroparesis and to develop a mouse model of targeted ablation of the pyloric enteric nervous system
Publications:

Bhave S, Arciero E, Baker C, Ho WL, Guyer RA, Hotta R, Goldstein AM. Pan-enteric neuropathy and dysmotility are present in a mouse model of short-segment Hirschsprung disease and may contribute to post-pullthrough morbidity. J Pediatr Surg. 2020 Apr 17.

Jayawardena ADL, Miller LE, Hirner L, Sorbo J, Zar-Kessler C, Baker C, Hartnick CJ. Modified external approach to the pediatric cricopharyngeal myotomy: A case series. Int J Pediatr Otorhinolaryngol. 2020 Jan 24;132:109899.

Katherine Baldwin, MD
Current Position: Connecticut Children’s Hospital
Research while at MGHfC:To determine the roles of PAK-1 phosphorylation in experimental colitis and to determine the role of MIP-1α and MIP-1β in experimental colitis
Publications:

Baldwin KR, Kaplan JL. Medical management of pediatric inflammatory bowel disease. Semin Pediatr Surg. 2017 Dec;26(6):360-366.

Lyons J, Brubaker DK, Ghazi PC, Baldwin KR, Edwards A, Boukhali M, Strasser SD, Suarez-Lopez L, Lin YJ, Yajnik V, Kissil JL, Haas W, Lauffenburger DA, Haigis KM. Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis. Sci Signal. 2018 Feb 27;11(519).

Lyons J, Ghazi PC, Starchenko A, Tovaglieri A, Baldwin KR, Poulin EJ, Gierut JJ, Genetti C, Yajnik V, Breault DT, Lauffenburger DA, Haigis KM. The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile. PLoS Biol. 2018 Mar 29;16(3):e2002417.

Logan Jerger, MD
Current Position: Connecticut Children’s Hospital
Research while at MGHfC: Re-programming bacteria to interrogate and potentially treat gastrointestinal disease
Publications:

Mimee M, Nadeau P, Hayward A, Carim S, Flanagan S, Jerger L, Collins J, McDonnell S, Swartwout R, Citorik RJ, Bulović V, Langer R, Traverso G, Chandrakasan AP, Lu TK. An ingestible bacterial-electronic system to monitor gastrointestinal health. Science. 2018 May 25;360(6391):915-918.

Batul Kaj, MD
Additional Training After MGHfC Fellowship: Transplant Hepatology Fellowship, Cincinnati Children’s Hospital
Current Position: Lurie Children’s Hospital
Research while at MGHfC: Determining the role of microRNA in modulating liver disease
Publications:

Duan X, Liu X, Li W, Holmes JA, Kruger AJ, Yang C, Li Y, Xu M, Ye H, Li S, Liao X, Sheng Q, Chen D, Shao T, Cheng Z, Kaj B, Schaefer EA, Li S, Chen L, Lin W, Chung RT. Microrna-130a Downregulates HCV Replication through an atg5-Dependent Autophagy Pathway. Cells. 2019 Apr 10;8(4).

Di Lorenzo C, Kaj B, Krishnan K, Moran CJ, Goldstein AM, Gee MS, Masia R. Case 29-2019: A 14-Month-Old Boy with Vomiting. N Engl J Med. 2019 Sep 19;381(12):1159-1167.

Shifra Koyfman, MD
Current Position: Associate Fellowship Program Director, Nicklaus Children’s Hospital
Research while at MGHfC: To define the role of a high fat diet in neurogenesis in a murine model
Publications:

Koyfman S, Swartz K, Goldstein AM, Staller K. Laparoscopic-Assisted Percutaneous Endoscopic Cecostomy (LAPEC) in Children and Young Adults. J Gastrointest Surg. 2017 Apr;21(4):676-683.

Mark Kusek, MD
Additional Training After MGHfC Fellowship: Motility Fellowship, Nationwide Children’s Hospital
Current Position: Children’s Hospital and Medical Center - Omaha
Research while at MGHfC: Using optical coherence tomography to study neutrophil migration through mucosal surfaces
Publications:

Chu KK, Kusek ME, Liu L, Som A, Yonker LM, Leung H, Cui D, Ryu J, Eaton AD, Tearney GJ, Hurley BP. Illuminating dynamic neutrophil trans-epithelial migration with micro-optical coherence tomography. Sci Rep. 2017 Apr 3;8:45789.

Kusek ME, Pazos MA, Pirzai W, Hurley BP. In vitro coculture assay to assess pathogen induced neutrophil trans-epithelial migration. J Vis Exp. 2014 Jan 6;(83):e50823.

Alejandro Llanos-Chea, MD
Current Position: Jackson Health System
Research while at MGHfC: To engineer a pathogen-specific bacteriophage to treat enteric infection using a human organoid model
Publications:

Szabady RL, Louissaint C, Lubben A, Xie B, Reeksting S, Tuohy C, Demma Z, Foley SE, Faherty CS, Llanos-Chea A, Olive AJ, Mrsny RJ, McCormick BA. Intestinal P-glycoprotein exports endocannabinoids to prevent inflammation and maintain homeostasis. J Clin Invest. 2018 Aug 31;128(9):4044-4056.

Llanos-Chea A, Fasano A. Gluten and Functional Abdominal Pain Disorders in Children. Nutrients. 2018 Oct 12;10(10).

Llanos-Chea A, Citorik RJ, Nickerson KP, Ingano L, Serena G, Senger S, Lu TK, Fasano A, Faherty CS. Bacteriophage Therapy Testing Against Shigella flexneri in a Novel Human Intestinal Organoid-Derived Infection Model. J Pediatr Gastroenterol Nutr. 2019 Apr;68(4):509-516.

Chanin RB, Nickerson KP, Llanos-Chea A, Sistrunk JR, Rasko DA, Kumar DKV, de la Parra J, Auclair JR, Ding J, Li K, Dogiparthi SK, Kusber BJD, Faherty CS. Shigella flexneri Adherence Factor Expression in In Vivo-Like Conditions. mSphere. 2019 Nov 13;4(6). pii: e00751-19.

Victoria Martin-Mackenzie, MD
Current Position: Co-Director, Pediatric Food Allergy Center, MassGeneral Hospital for Children
Research while at MGHfC: To study the incidence and pathophysiology of infantile allergic colitis in a birth cohort
Publications:

Martin VM, Virkud YV, Seay H, Hickey A, Ndahayo R, Rosow R, Southwick C, Elkort M, Gupta B, Kramer E, Pronchick T, Reuter S, Keet C, Su KW, Shreffler WG, Yuan Q. Prospective Assessment of Pediatrician-Diagnosed Food Protein-Induced Allergic Proctocolitis by Gross or Occult Blood. J Allergy Clin Immunol Pract. 2020 May;8(5):1692-1699

Su KW, Patil SU, Stockbridge JL, Martin VM, Virkud YV, Huang JL, Shreffler WG, Yuan Q. Food aversion and poor weight gain in food protein-induced enterocolitis syndrome: A retrospective study. J Allergy Clin Immunol. 2020 May;145(5):1430-1437

Martin VJ, Shreffler WG, Yuan Q. Presumed Allergic Proctocolitis Resolves with Probiotic Monotherapy: A Report of 4 Cases. Am J Case Rep. 2016 Aug 29;17:621-4.

Martin VJ, Leonard MM, Fiechtner L, Fasano A. Transitioning From Descriptive to Mechanistic Understanding of the Microbiome: The Need for a Prospective Longitudinal Approach to Predicting Disease. J Pediatr. 2016 Dec;179:240-248.

Maureen Leonard, MD
Current Position: Clinical Director of Celiac Disease Program, MassGeneral Hospital for Children
Research while at MGHfC: To determine pathophysiologic drivers of celiac disease in an at-risk birth cohort
Publications:

Leonard MM, Serena G, Sturgeon C, Fasano A. Genetics and celiac disease: the importance of screening. Expert Rev Gastroenterol Hepatol. 2015 Feb;9(2):209-15.

Leonard MM, Camhi S, Huedo-Medina TB, Fasano A. Celiac Disease Genomic, Environmental, Microbiome, and Metabolomic (CDGEMM) Study Design: Approach to the Future of Personalized Prevention of Celiac Disease. Nutrients. 2015 Nov 11;7(11):9325-36.

Leonard MM, Weir DC, DeGroote M, Mitchell PD, Singh P, Silvester JA, Leichtner AM, Fasano A. Value of IgA tTG in Predicting Mucosal Recovery in Children With Celiac Disease on a Gluten-Free Diet. J Pediatr Gastroenterol Nutr. 2017 Feb;64(2):286-291.

Leonard MM, Cureton P, Fasano A. Indications and Use of the Gluten Contamination Elimination Diet for Patients with Non-Responsive Celiac Disease. Nutrients. 2017 Oct 18;9(10).

Rajitha Venkatesh, MD
Current Position: Duke University School of Medicine
Research while at MGHfC: Studying the risk factors involved in the development of celiac disease and assessing the value of e-consults in gastroenterology care
Publications:

Venkatesh RD, Campbell EJ, Thiim M, Rao SK, Ferris TG, Wasfy JH, Richter JM. e-Consults in gastroenterology: An opportunity for innovative care. J Telemed Telecare. 2019 Sep;25(8):499-505.

Navneet Virk Hundal, MD
Current Position: Co-Director, Pediatric Food Allergy Center, MassGeneral Hospital for Children
Research while at MGHfC: Studying the role of T cell receptor rearrangement in eosinophilic esophagitis
Publications:

Katz A, Virk Hundal N, Yuan Q, Shreffler W. Cow's milk allergy: a new approach needed? J Pediatr. 2013 Sep;163(3):620-2.

Claire Zar-Kessler, MD
Current Position: Director of Neurogastroenterology, MassGeneral Hospital for Children
Research while at MGHfC: Determining the role of anorectal manometry in pediatric defecatory disorders
Publications:

Zar-Kessler C, Karaa A, Sims KB, Clarke V, Kuo B. Understanding the gastrointestinal manifestations of Fabry disease: promoting prompt diagnosis. Therap Adv Gastroenterol. 2016 Jul;9(4):626-34.

Zar-Kessler CAM, Belkind-Gerson J, Bender S, Kuo BM. Treatment of Functional Abdominal Pain With Antidepressants: Benefits, Adverse Effects, and the Gastroenterologist's Role. J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):16-21.

Zar-Kessler C, Kuo B, Belkind-Gerson J. Botulinum toxin injection for childhood constipation is safe and can be effective regardless of anal sphincter dynamics. J Pediatr Surg. 2018 Apr;53(4):693-697.

Zar-Kessler C, Kuo B, Cole E, Benedix A, Belkind-Gerson J. Benefit of Pelvic Floor Physical Therapy in Pediatric Patients with Dyssynergic Defecation Constipation. Dig Dis. 2019;37(6):478-485.