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Children with a chronic illness benefit from a multidisciplinary approach to their care. We have built a team with expertise in diagnosing and managing children and adolescents with inflammatory bowel disease (IBD).
Patients are cared for by an IBD team that includes:
These specialists work together in a single program to provide a comprehensive approach to the care of your child. Every patient requires individualized care reflecting this individuality. We strive to incorporate current evidence-based guidelines and ongoing clinical, translational, and basic science research to offer the most up-to-date treatment options for our patients.
Patient evaluation involves a detailed history and exam. Further testing may include blood testing, endoscopic testing, and radiologic studies. If your child needs a procedure (endoscopy or radiology study), our Child Life specialists will insure that you and your child’s experience is as easy as possible. In February 2012, we opened a new, state-of-the-art Pediatric Endoscopy unit with the newest equipment in a friendly and appropriate space for children, adolescents and their families.
An evaluation may also include radiology studies such as Upper GI series, Magnetic Resonance Enteroscopy (MRE), as well as other imaging techniques when indicated. Our colleagues in Pediatric Radiology use techniques that significantly limit radiation exposure to pediatric patients without compromising the quality of the study.
Our IBD Program also has an active research program in which patients will have the opportunity to participate in research studies trying to understand the relationship between IBD, intestinal bacteria, genetic factors, and the role that certain diets have on IBD. Our center has been selected to participate in many clinical trials of new medications for children who may not have responded to currently approved and available treatments.
Our Program’s Philosophy
Crohn’s disease is diagnosed more frequently in young adults than in children, but children can develop Crohn’s. Crohn’s disease is a form of inflammatory bowel disease (IBD) that can affect different parts of the gastrointestinal tract from the mouth to the anus. The most common part of the digestive tract to become inflamed is the lower part of the small bowel, called the ileum. Other common areas include the esophagus, stomach, duodenum, appendix, and colon.
Crohn’s disease does not have to affect the entire gastrointestinal tract (and rarely does). It can “skip” areas (normal areas between two inflamed areas). The inflammation goes deep into the tissues of the digestive tract and alters the entire thickness of the intestinal walls.
Ulcerative Colitis is a form of inflammatory bowel disease (IBD) that mostly affects the large intestine (colon). A special feature of ulcerative colitis is that it always starts in the rectum. The inflammation is also continuous, which means there are no skipped areas like there can be in Crohn’s disease. Ulcerative colitis affects only the innermost layer of the bowel wall, called the mucosa, and the inflammation does not penetrate through the other layers (as it does in Crohn’s).
Crohn's disease is an inflammatory bowel disease that is a chronic condition that may recur at various times over a lifetime.
Ulcerative colitis is an inflammatory bowel disease in which the inner lining of the large intestine (colon or bowel) and rectum become inflamed.
Safety and effectiveness registry for adalimumab (Humira)
Long-term (20 years) safety registry for infliximab (Remicade)
Genetics of very early onset IBD
Role of the genetic markers to determine response to treatment with mesalamine
Efficacy study of mesalamine (Lialda) for treatment of mild to moderate ulcerative colitis
Efficacy study of adalimumab (Humira) for treatment of moderate to severe ulcerative colitis
Role of the microbiome as a biomarker for progression of IBD
Role of the microbiome in patients with primary sclerosing cholangitis
Role of the microbiome in children with perianal Crohn’s disease
Effectiveness of the addition of methotrexate in Crohn’s disease patients starting anti-TNFα therapy
Infliximab dose escalation in children with Crohn’s disease and ulcerative colitis
Liam's lemonade stand support his physician's work and MGHfC IBD Parents Group receives $5,000 for outreach and education
Dr. Moran is a pediatric gastroenterologist who practices clinically in the Pediatric Inflammatory Bowel Disease Programs at MassGeneral Hospital for Children and Newton Wellesley Hospital. He conducts clinical and basic science research to better understand the cause of inflammatory bowel disease (IBD).
Pediatric Inflammatory Bowel Disease Center Yawkey Center for Outpatient Care Suite 6B 32 Fruit Street, Boston, MA 02114
Patients or healthcare providers may call the Inflammatory Bowel Disease Center by calling 1-877-PEDI-IBD (877-733-4423) and the staff will call your patient within 1 business day.
Patients may also call the Pediatric GI Call Center at 617-726-8705 to schedule an appointment.
Yawkey Building 55 Fruit Street Suite 6B Boston, MA 02114
Newton Wellesley Hospital 6 South 2000 Washington Street Newton, MA
Public Transportation Access: yes Disabled Access: yes
Medical Infusion Unit MGH-West 40 Second Avenue, Suite 300 Waltham, MA 02451
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