Restless Legs Syndrome (RLS)
Restless legs syndrome is a sleep disorder that causes creepy, crawly feelings in your legs. This often happens when you are trying to go to sleep or have been sitting for a long time.
Fireman Vascular Center
Mass General Vein Care provides expert vein care to patients with cosmetic and non-cosmetic venous disease, including varicose veins and spider veins. Consultation and services are available in Boston, Waltham, Stoneham, and Danvers.
Welcome to the Massachusetts General Hospital Parkinson's Disease and Movement Disorder Clinic. We are committed to providing the highest quality of care for Parkinson's disease and related conditions.
The Sleep Disorders Clinical Research Program at Massachusetts General Hospital is dedicated to clinical and investigative efforts in sleep disorders, including restless legs syndrome, insomnia and sleep-related eating disorder.
Department of Medicine
The Spaulding Sleep Center uses the latest technology to diagnose and treat sleep disorders, with a focus on patients with cardiac and/or pulmonary disease.
Restless Legs Syndrome (RLS)
What is RLS?
Restless legs syndrome is a problem (disorder) that affects the nervous system and muscles.. It causes unpleasant sensations in the legs. The sensations are described as:
You usually have these sensations in the calf, but they may be felt anywhere from the thigh to the ankle. One or both of your legs may be affected. Some people may have the sensations in the arms. With RLS, you have an irresistible urge to move the affected limb when the sensations occur. Moving often briefly relieves the limb discomfort.
Sleep problems are common with RLS because of the difficulty it causes in getting to sleep. Severe daytime fatigue can also be a big problem.
What causes RLS?
The cause of RLS is still unknown. Some cases are believed to be inherited. Some cases have been linked with nerve damage in the legs from diabetes, kidney problems, iron deficiency, certain medicines, pregnancy, sleep disorders, and alcoholism.
It's estimated that as many as 1 in 10 people in the U.S. may have RLS in varying degrees of severity.
What are the symptoms of RLS?
Sensations occur when you lie down or sit for a prolonged time. This causes:
The need to move the legs for temporary relief of symptoms by:
Stretching or bending
Rubbing the legs
Tossing or turning in bed
Getting up and pacing
Worsening symptoms when lying down, especially when trying to fall asleep at night, or during other forms of inactivity, including just sitting
A tendency to feel the most discomfort late in the day and at night
How is RLS diagnosed?
Your healthcare provider can diagnose RLS based on your signs and symptoms, a complete medical history, and a physical exam. In addition, tests, such as lab tests or a sleep study, may be done. Currently, there is not a definitive test to diagnose restless legs syndrome.
How is RLS treated?
Your healthcare provider will consider your age, overall health and other factors when advising treatment for you.
Treatment options for restless legs syndrome may include:
Trying good sleep habits
Stopping activities that worsen symptoms
Giving up caffeine, alcohol, and tobacco. These may make symptoms worse.
Regular, moderate exercise
Maintaining a well-balanced diet
Treating underlying chronic conditions
Dopaminergic medicines. These are medicines that increase dopamine and are largely used to treat Parkinson disease.
Benzodiazepines such as clonazepam and diazepam
Opioids such as codeine, propoxyphene, and oxycodone
Anticonvulsants such as gabapentin and pregabalin
Iron therapy. Some people respond to iron therapy.
Talk with your healthcare provider for more information on how restless legs syndrome is treated.
Key points about restless legs syndrome
Restless legs syndrome is a disorder that causes unpleasant sensations in the legs. The cause of RLS is still unknown.
With RLS, you have an irresistible urge to move the affected limb when the sensations occur.
Your healthcare provider can diagnose RLS based on your symptoms, a health history, and a physical exam, but there is no definitive test to diagnose RLS.
Medicine and lifestyle changes can help ease RSL symptoms.
Tips to help you get the most from a visit to your healthcare provider:
Know the reason for your visit and what you want to happen.
Before your visit, write down questions you want answered.
Bring someone with you to help you ask questions and remember what your provider tells you.
At the visit, write down the name of a new diagnosis, and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you.
Know why a new medicine or treatment is prescribed, and how it will help you. Also know what the side effects are.
Ask if your condition can be treated in other ways.
Know why a test or procedure is recommended and what the results could mean.
Know what to expect if you do not take the medicine or have the test or procedure.
If you have a follow-up appointment, write down the date, time, and purpose for that visit.
Know how you can contact your provider if you have questions.
News & Publications
The purpose of this study was to quantify and describe the amount of waste generated by an Emergency Department, identify deviations from waste policy and explore areas for waste reduction.
Our publication keeps health care professionals up to date on the latest research and clinical advances from Mass General.
News and notes from the largest hospital-based research program in the United States
The Patient Gateway provides secure online access to your health information whenever you need it. Check upcoming appointments, communicate with your doctor’s office, review medications and pay medical bills—all seamlessly online 24/7.