About Jonathan Winograd, MD

Jonathan Winograd was born in Lynn, Massachusetts in 1966.  He grew up in Marblehead and graduated from Saint John’s Preparatory School as salutatorian in 1984. He attended Harvard College and graduated Magna Cum Laude in Biology in 1988, and Harvard Medical School, earning his medical degree in 1992.  He then entered a combined general surgery/plastic surgery residency at Johns Hopkins Hospital and the University of Maryland/Shock Trauma Center in Baltimore, Maryland.  During that time, he was a research fellow under the mentorship of Dr. Paul Manson and Dr. Craig Vander Kolk, both internationally renowned craniofacial surgeons, and Dr. Gregg Semenza, a molecular biologist and recipient of the Nobel Prize in Physiology or Medicine in 2019.  Dr. Winograd then completed a fellowship in Hand and Microsurgery at Washington University in Saint Louis led by Dr. Susan Mackinnon, an internationally recognized expert in Peripheral Nerve Surgery.

Dr. Winograd joined the staff of the MGH and Shriners Hospital for Children in 2001. He has an active clinical practice which encompasses the whole spectrum of plastic and reconstructive surgery, including patients with surgical problems of the breast and body, the hand and upper and lower extremities, and cosmetic procedures.  He has developed a particular focus on reconstructive problems of the peripheral nervous system, such as brachial plexus injuries, thoracic outlet syndrome, and nerve compressions including carpal tunnel and cubital tunnel syndromes.  These also include microsurgical nerve reconstruction after nerve injuries of the extremities and other regions of the body as well as the surgical treatment of chronically painful conditions such as neuropathy or nerve injuries known as neuromas.  He is the Director of an active basic science translational research program as well as a clinical research program aimed at improving outcomes after peripheral nerve injuries, and he is the recipient of multiple grant awards from the Consortium for Improving Medicine with Innovation and Technology (a consortium comprised of leading academic scientists and clinicians from MIT, MGH and other Boston area institutions), the DOD, and the NIH.  He is the current President of the Massachusetts Society of Plastic Surgeons and is the Secretary and an Executive Board member of the American Society of Peripheral Nerve.  He has offices in Boston and Danvers. 

Clinical Interests:




Mass General Surgery: Plastic & Reconstructive Surgery
55 Fruit St.
Wang Ambulatory Care Center
Suite 435
Boston, MA 02114
Phone: 617-726-1915

Mass General Brigham Healthcare Center
52 Second Ave.
Waltham, MA 02451
Phone: 877-424-5678

Medical Education

  • MD, Harvard Medical School (Massachusetts)
  • Residency, Johns Hopkins Hospital***
  • Fellowship, Barnes Jewish Hospital

American Board Certifications

  • Hand Surgery, American Board of Plastic Surgery
  • Plastic Surgery, American Board of Plastic Surgery

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


My laboratory investigates emerging technologies and their translation into clinical practice to improve outcomes of peripheral nerve reconstruction and regeneration. 

Previous work investigated stem cell transplantation into muscles to prevent atrophy after injury.  Muscles that have lost their neural input from injury or disease would be protected from severe, irreversible atrophy in order to improve reconstructive outcomes after they recover.  Separate work in collaboration with the Bizzi Lab at MIT developed a model to investigate a novel Brain Body Interface (BBI), which would allow for restoration of voluntary limb control directly from the motor cortex of the brain in spinal cord-injured patients who have lost that function from their injury.

More recently, the technique of photochemical tissue bonding (PTB), in which tissues are bonded together using light to activate a chemical dye, has been applied to the microsurgical repair of peripheral nerves.  The dye is able to form covalent bonds without the use of sutures to hold the tissues together. This limits scar tissue formation at the repair and also results in faster and more complete regeneration of the nerve fibers and better outcomes in animal models of nerve repair. This technique is now ready for evaluation in clinical trials, which may lead to clinical application to complex nerve reconstruction and the potential for better outcomes from nerve injuries following reconstruction.  



    Please refer to PubMed link to review the 65 peer reviewed publications of Dr. Winograd.  Below are full information for two of the most recent publications. 


    Surgical management and epidemiological trends of pediatric electrical burns.


    Depamphilis MA, Cauley RP, Sadeq F, Lydon M, Sheridan RL, Driscoll DN, Winograd JM.


    Burns. 2020 Mar 31.



    Wide-Field Functional Microscopy of Peripheral Nerve Injury and Regeneration.


    Nam AS, Easow JM, Chico-Calero I, Villiger M, Welt J, Borschel GH, Winograd JM, Randolph MA, Redmond RW, Vakoc BJ.


    Sci Rep. 2018 Sep 18;8(1):14004.

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