关于新型冠状病毒疫苗过敏反应的常见问题解答
12月,美国食品和药物管理局(FDA)批准了辉瑞/拜恩泰科(Pfizer/BioNTech)与莫德纳(Moderna)的新型冠状病毒疫苗在美国的紧急使用授权,目前这两款疫苗在全美范围内开始分发。在疫苗初步推行后,美国和英国出现了少量过敏反应的报告。本文就对这些有关初期过敏反应报告的常见问题给出指导和解答。
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Dr. Banerji is an Associate Professor at Harvard Medical School and Clinical Director of the Allergy and Clinical Immunology Unit at MGH. Dr. Banerji is an Allergist and Immunologist with a special interest in drug allergy and angioedema. She has a national reputation as an expert in these fields, with invited talks in both areas at regional, national and international conferences. Dr. Banerji has built a formal drug allergy program in the outpatient allergy clinic at MGH to better manage patients with drug hypersensitivity reactions. She leads the inpatient desensitization program for patients with reactions to chemotherapeutics and monoclonal antibodies. As part of this drug allergy program, she collects standardized data on all patients we evaluate for drug hypersensitivity in order to identify risk factors for true hypersensitivity and improve drug allergy diagnosis with skin testing and challenges. In 2013, Dr. Banerji was invited to participate in an NIH workshop geared towards developing a prioritized research agenda on drug allergy and a summary of this meeting was published in August 2015 in the Journal of Allergy and Clinical Immunology. As an angioedema expert, Dr Banerji has collaborated with industry on multiple novel agents for hereditary angioedema and has published >50 peer-reviewed manuscripts including national and international guidelines for the management of angioedema. Dr. Banerji has actively participated as an investigator on multiple large clinical trials in hereditary angioedema, several of which were investigator initiated studies and including one study published by the NEJM in 2017 and another in JAMA in 2019 as a first author.
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Mass General Medicine: Allergy & Clinical Immunology Unit
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Dr. Banerji's work focuses on drug allergy and angioedema. Specifically, Dr. Banerji has worked on improving the diagnosis and management of patients presenting with drug reactions to a variety of medications including antibiotics, aspirin, chemotherapeutic agents, monoclonal antibiotics and anesthetic agents. In the field of angioedema, Dr. Banerji has a particular interest in hereditary angioedema to improving care, improve quality of life and decreasing burden of disease.
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12月,美国食品和药物管理局(FDA)批准了辉瑞/拜恩泰科(Pfizer/BioNTech)与莫德纳(Moderna)的新型冠状病毒疫苗在美国的紧急使用授权,目前这两款疫苗在全美范围内开始分发。在疫苗初步推行后,美国和英国出现了少量过敏反应的报告。本文就对这些有关初期过敏反应报告的常见问题给出指导和解答。
In a multi-hospital analysis of individuals who experienced an allergic reaction to their first mRNA COVID-19 vaccine dose, all patients who went on to receive a second dose tolerated it without complications.
These reactions should not discourage patients from getting the vaccine, researchers say.
At the end of 2020, allergists examined all information related to possible allergic reactions to COVID-19 vaccinations. Now the team has published updated insights based on their experience overseeing more than 65,000 employees who have become fully vaccinated since that time.
Data on mRNA COVID-19 vaccinations among employees at Mass General Brigham provide reassurances of the rarity of serious reactions, and the ability to recover from them.
A small number of allergic reactions were reported of the two COVID vaccines in distribution. The Allergy & Clinical Immunology departments at Massachusetts General Hospital and Brigham and Women’s Hospital offer answers to questions regarding these reports of allergic reaction.