About Florence (Katie) Keane, MD

Dr. Keane is an attending Radiation Oncologist at Massachusetts General Hospital and an Assistant Professor of Radiation Oncology at Harvard Medical School. She graduated from the University of Virginia with high honors and was elected to Phi Beta Kappa in her third year. She received her MD with honors from Yale University School of Medicine, winning the American Cancer Society Prize for an outstanding thesis in the area of Oncology. After completing her intern year in Internal Medicine at Massachusetts General Hospital, she then completed her residency training at the Harvard Radiation Oncology Program. 

She specializes in the treatment of thoracic tumors, including lung cancer, esophageal cancer, metastases to the lung, and rare thoracic tumors such as thymoma, thymic carcinoma and mesothelioma. She also specializes in the treatment of melanoma, including choroidal melanoma. She is active in research, with a particular focus on the use of immunotherapy and targeted therapies with radiotherapy. 

Departments, Centers, & Programs:

Clinical Interests:



Clark Center for Radiation Oncology
100 Blossom Street
Boston, MA 02114-2606
Phone: 617-726-5184
Fax: 617-726-3603

Medical Education

  • MD, Yale University School of Medicine
  • Residency, Massachusetts General Hospital
  • Fellowship, Harvard Medical School

American Board Certifications

  • Radiation Oncology, American Board of Radiology

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


View my most recent research: http://www.ncbi.nlm.nih.gov/pubmed/?term=keane%2C+florence+k


Dr. Keane's research focuses on the combination of radiotherapy with systemic therapy, including immunotherapy and targeted therapies. 

Dr. Keane is the site Principal Investigator for a Randomized Trial of SBRT with or without Pembrolizumab in patients with early-stage lung cancer. More information can be found at : https://clinicaltrials.gov/ct2/show/NCT03924869?term=SBRT+pembrolizumab&cond=Lung+Cancer+Stage+I&draw=2&rank=1