Dr. Keane is an attending Radiation Oncologist at Massachusetts General Hospital and an Assistant Professor of Radiation Oncology at Harvard Medical School. She graduated from the University of Virginia with high honors and was elected to Phi Beta Kappa in her third year. She received her MD with honors from Yale University School of Medicine, winning the American Cancer Society Prize for an outstanding thesis in the area of Oncology. After completing her intern year in Internal Medicine at Massachusetts General Hospital, she then completed her residency training at the Harvard Radiation Oncology Program. 

She specializes in the treatment of thoracic tumors, including lung cancer, esophageal cancer, metastases to the lung, and rare thoracic tumors such as thymoma, thymic carcinoma and mesothelioma. She also specializes in the treatment of melanoma, including choroidal melanoma. She is active in research, with a particular focus on the use of immunotherapy and targeted therapies with radiotherapy.