Departments, Centers, & Programs:
55 Fruit Street
Boston, MA 02114-2696
- MD, PhD, Harvard Medical School
- Residency, Massachusetts General Hospital
- Fellowship, Brigham and Women's Hospital
American Board Certifications
- Clinical Pathology, American Board of Pathology
Accepted Insurance Plans
Lareau, C.A., Clement, K., Hsu, J.Y., Pattanayak, V., Joung, J.K., Aryee, M.J., Pinello, L. Response to “Unexpected mutations after CRISPR-Cas9 editing in vivo.” Nature Methods. 15: 238, 2018.
Kleinstiver, B.P.*, Pattanayak, V.*, Prew, M.S., Tsai, S.Q., Nguyen, N.T., Zheng, Z., Joung, J.K. High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects. Nature. 529: 490, 2016.
Pattanayak, V.*, Guilinger, J.P.*, Liu, D.R. Determining the specificities of TALENs, Cas9, and other genome-editing enzymes. Methods in Enzymology. 546: 47, 2014.
Guilinger, J.P., Pattanayak, V., Reyon, D., Tsai, S.Q., Sander, J.D., Joung, J.K., Liu, D.R. Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity. Nature Methods. 11: 429, 2014.
Pattanayak, V., Lin, S., Guilinger, J.P., Ma, E., Doudna, J.A., Liu, D.R. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nature Biotechnology. 31: 839-843, 2013.
Pattanayak, V., Ramirez, C.L., Joung, J.K., Liu, D.R. Revealing off-target cleavage specificities of zinc finger nucleases by in vitro selection. Nature Methods. 9: 765-770, 2011.
Doyon, J.B., Pattanayak, V., Meyer, C.B., Liu, D.R. Directed evolution and substrate specificity profile of homing endonuclease I-SceI. J. Am. Chem. Soc. 128: 2477-84, 2006.