About Nazlee Zebardast, MD

Dr. Zebardast is a clinician scientist and full-time member of the Glaucoma Service at Mass Eye and Ear. She specializes in the treatment of adult glaucoma and combined glaucoma and cataracts, with a particular interest in minimally invasive glaucoma surgeries (MIGS).

She has received numerous awards and honors for her academic and research accomplishments and has published in top ophthalmology journals. With a focus on global health and epidemiology research, she has worked with researchers at Aravind Eye Institute in India to study angle-closure glaucoma, a blinding eye disease. Among other findings, this study determined that siblings of individuals with known angle closure have a greater than 1 in 3 risk of developing the condition. Additionally, she has worked with a many large datasets to understand the prevalence of eye disease and its impact. She plans to use imaging to better understand glaucoma progression in angle-closure eyes and to use big data and machine learning methodologies to detect glaucoma and characterize its progression.

Departments, Centers, & Programs:

Clinical Interests:



Massachusetts Eye and Ear Infirmary
243 Charles Street
Boston, MA 02114 - 3002
Phone: 617-573-3689
Fax: 617-573-6965

Massachusetts Eye and Ear Stoneham
1 Montvale Avenue
Suite 501
Stoneham, MA 02180
Phone: 781-279-4418
Fax: 617-573-5607

Mass Eye and Ear Waltham
1601 Trapelo Rd.
Suite 184
Waltham, MA 02451
Phone: 781-890-1023
Fax: 781-890-2507

Medical Education

  • MD, Yale University
  • MD, Yale University School of Medicine
  • Residency, The Johns Hopkins Hospital
  • Residency, Wilmer Eye Institute at Johns Hopkins
  • Fellowship, The Johns Hopkins Hospital
  • Fellowship, Wilmer Eye Institute at Johns Hopkins

American Board Certifications

  • Ophthalmology, Royal College of Physicians and Surgeons of Canada
  • Ophthalmology, American Board of Ophthalmology

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Dr. Zebardast’s research focuses on epidemiology and global health. Working with international colleagues, she established a multicenter trial to study angle-closure glaucoma. Additionally, she has used large datasets and statistical methods to understand the prevalence of eye disease and its functional impact.

Currently, she aims to use anterior segment imaging, in particular swept source OCT technology, to better understand angle-closure glaucoma progression. Additionally, she plans to use big data and machine learning methodologies for glaucoma detection and characterization of progression. She hopes that this work will not only optimize glaucoma diagnosis, but also help establish care in under-served regions, thereby decreasing the global burden of this disease.


  • 1. Kempen JH, Pistilli M, Begum H, Fitzgerald TD, Liesegang TL, Payal A, Zebardast N, Bhatt NP, Foster CS, Jabs DA, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Sen HN, Suhler EB, Thorne JE. Remission Of Non-Infectious Anterior Scleritis: Incidence And Predictive Factors. Am J Ophthalmol. 2019 Apr 02.

    2. Kavitha S, Ramulu PY, Venkatesh R, Palaniswamy K, Kader MA, Raman GV, Rajendrababu S, Zebardast N. Resolution of Visual Dysphotopsias after Laser Iridotomy: Six-Month Follow-up. Ophthalmology. 2019 03; 126(3):469-471.e1. 

    3. Mudie LI, Varadaraj V, Gajwani P, Munoz B, Ramulu P, Lin FR, Swenor BK, Friedman DS, Zebardast N. Dual sensory impairment: The association between glaucomatous vision loss and hearing impairment and function. PLoS One. 2018; 13(7):e0199889. 

    4. Srinivasan K, Zebardast N, Venkatesh R, Ramulu PY. Reply. Ophthalmology. 2018 05; 125(5):e36-e37.

    5. Srinivasan K, Zebardast N, Krishnamurthy P, Abdul Kader M, Raman GV, Rajendrababu S, Venkatesh R, Ramulu PY. Comparison of New Visual Disturbances after Superior versus Nasal/Temporal Laser Peripheral Iridotomy: A Prospective Randomized Trial. Ophthalmology. 2018 03; 125(3):345-351. 

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