About Raghu Chivukula, MD

Dr. Chivukula studied cellular and molecular neuroscience at Johns Hopkins University prior to MD and PhD training in genetics at Johns Hopkins University School of Medicine. He undertook residency training in internal medicine at Massachusetts General Hospital, clinical fellowships in pulmonary disease and critical care medicine at Harvard Medical School, and a postdoctoral research fellowship at the Whitehead Institute for Biomedical Research.

 

As an Instructor of Medicine at Harvard Medical School and an attending physician at Massachusetts General Hospital, Dr. Chivukula is actively involved in clinical care, research, and teaching. Dr. Chivukula’s clinical interests include general critical care medicine, genetic forms of lung disease, and the MGH Pathways Program - which identifies unusual and extreme clinical phenotypes to initiate new lines of investigation led by physician-scientists. His laboratory research interests center on the function and dysfunction of specialized organelles in the lung, particularly in rare pulmonary disorders. Finally, as an educator, Dr. Chivukula participates in teaching HMS medical students, Harvard and MIT graduate students, and MGH residents/fellows in didactic and clinical settings. 

Departments, Centers, & Programs:

Clinical Interests:

Treats:

Locations

Boston: Massachusetts General Hospital

55 Fruit Street
Boston, MA 02114
Phone: 617-726-2000

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Medical Education

  • MD, Johns Hopkins University School of Medicine
  • Residency, Massachusetts General Hospital
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Pulmonary Disease, American Board of Internal Medicine
  • Internal Medicine, American Board of Internal Medicine
  • Critical Care Medicine, American Board of Internal Medicine

Accepted Insurance Plans

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Research

View my most recent research

Dr. Chivukula conducts basic scientific research in the Sabatini group at the Whitehead Institute for Biomedical Research. His prior work has elucidated novel in vivo roles for microRNAs in mammals and revealed a previously undescribed form of human lung disease caused by short airway cilia. His current work focuses on the roles of lysosome dysfunction in driving genetic and sporadic forms of interstitial lung disease. Dr. Chivukula’s research has been recognized with the Michael A. Shanoff Award, selection to Forbes Magazine “30 Under 30”, selection as a fellow of the Parker B. Francis Foundation, and the Burroughs Wellcome Career Award for Medical Scientists.

Publications

  • View my most recent publications at PubMed

    Chivukula RR*, […] Alkuraya FS*, Sabatini DM. A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance. Nature Medicine. 26(2), 244-251 (2020). *corresponding
     
    Chivukula RR, Maley JH, Dudzinski DM, Hibbert, KA, Hardin, CC. Evidence-based management of the critically ill adult with SARS-CoV-2 infection. Journal of Intensive Care Medicine. 10.1177/0885066620969132 (2020).
     
    Taylor MS*, Chivukula RR*, [...] Kradin RL. Delayed alveolar epithelialization: a distinct pathology in diffuse acute lung injury. Am. J. Respir. Crit. Care Med. 197, 522–524 (2018). *equal contribution
     
    Chivukula RR*, Shi G*, [...] Mendell JT. An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell 157, 1104-16 (2014). *equal contribution
     
    Kota J, Chivukula RR, [...] Mendell JT. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137, 1005–1017 (2009).