The Endocrine and Osteoporosis Associates Practice

Endocrine and Osteoporosis Associates

Endocrine and Osteoporosis Associates at Massachusetts General Hospital provides comprehensive diagnostic and therapeutic services for patients with endocrine disorders, osteoporosis and related metabolic bone diseases.


A Personalized Clinical Approach

At Massachusetts General Hospital Endocrine and Osteoporosis Associates, our endocrinologists provide preventative services and state-of-the art treatment for endocrine disorders, osteoporosis and related metabolic bone diseases. We tailor our clinical approach to each patient’s needs.

If your primary endocrine problem is diabetes, please refer to the Diabetes Clinical Center.

What to Expect

Our providers take a collaborative approach to care, working closely with one another, your referring provider and you to diagnose your condition and determine the most effective treatment.

At your first appointment, your Endocrine and Osteoporosis Associates physician will review your medical history and complete a physical examination and diagnostic evaluation. To facilitate this, we require a referral for all new patients, and we request that your referring provider fax pertinent medical history to 617-724-2718, before your appointment.

In addition, please bring all relevant records, X-rays and medication lists to your first appointment. If you have osteoporosis, please bring previous bone density reports.

We offer a range of diagnostic testing services, include dynamic endocrine testing, in which we take measurements after giving medication to stimulate or suppress a response.

We also provide many treatment options. For example, if you have osteoporosis and oral drugs have been ineffective or caused side effects, we can prescribe alternative treatments (e.g. intravenous therapies or other medications). Rather than referring you to an outside infusion center, we can perform drug infusion onsite.

After treatment has begun, most patients receive ongoing care at Endocrine and Osteoporosis Associates. In some instances, patients are seen just once and then referred back to their primary care physician.

If you have an adrenal, parathyroid or thyroid tumor, you may need to be seen by an endocrine surgeon. In these cases, we can refer you to the Mass General Endocrine Surgery Program for prompt evaluation.

About this Program

Leaders in Research and Clinical Care

Massachusetts General Hospital Endocrine and Osteoporosis Associates conducts diagnostic testing, including dynamic endocrine testing, to identify your endocrine condition. Our endocrinologists are skilled in recommending alternative therapies when other medications have been ineffective or caused side effects. We often manage ongoing care for patients, including onsite drug infusion.

Endocrine and Osteoporosis Associates is part of the Mass General Endocrine Unit, one of the largest such programs in the United States. Most of our Harvard Medical School physician-scientists are national leaders in basic or clinical research and play a major role in developing new treatments for endocrine disorders and osteoporosis. They also have extensive experience in treating other endocrine conditions, including genetic disorders related to mineral metabolism and rare diseases such as hypoparathyroidism.

Benjamin Leder, MD, has served as our medical director since 2008. Dr. Leder earned his medical degree from Harvard Medical School and completed his residency and clinical and research fellowships at Mass General. He has been active in endocrine research since 2000, and was elected to the American Society of Clinical Investigators, a prestigious honor society of physician-scientists, in 2011.

A Commitment to the Future of Osteoporosis Treatment

Our endocrinologists regularly conduct clinical trials, most commonly for osteoporosis. Patients are welcome to enroll in these trials, which often provide access to leading-edge treatments. The trials are independent of the clinical care delivered by Endocrine and Osteoporosis Associates, and participation is not required.

For information on clinical trials that may be appropriate for you, please speak with your Endocrine and Osteoporosis Associates physician.

As part of an academic medical center, Endocrine and Osteoporosis Associates is committed to training the next generation of endocrinologists. Through the Endocrinology Fellowship Program, clinical fellows see patients alongside the attending physician and offer insight into patient care.

Conditions & Diseases

  • Hyperparathyroidism

    Hyperparathyroidism is caused by overactive parathyroid glands. Overactive parathyroid glands produce too much parathyroid hormones, which in turn stimulate increased levels of calcium in the blood stream.

  • Hypoglycemia (Low Blood Sugar)

    Hypoglycemia is a condition characterized by a glucose (blood sugar) level that is too low to effectively fuel the body's blood cells.

  • Hypoparathyroidism

    Underactive parathyroid glands do not produce enough parathyroid hormones. This causes low levels of calcium in the blood.

  • Osteoporosis

    Osteoporosis, or porous bone, is a disease in which there is a loss of bone mass and destruction of bone tissue, causing weakening of the bones in the hips, spine and wrists.

Clinical Trials


Contact Us

Endocrine and Osteoporosis Associates

Wang Ambulatory Care Center

WACC 73015 Parkman Street Boston, MA 02114
  • Near Public Transit
  • Accessible
  • Phone: 617-726-8720
  • Fax: 617-724-2718


  • 8:00 am-4:30 pm

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