Endocrine Unit Research
The Bastepe Lab strives to improve clinical management of endocrine and musculoskeletal disorders through fundamental research that involves genetics and molecular and cell biology.
The Demay Laboratory at Massachusetts General Hospital is focused on understanding the role of the vitamin D receptor (VDR) in skeletal maturation and in cutaneous homeostasis.
The Kobayashi Laboratory at Massachusetts General Hospital investigates the genetics of skeletal development.
Dr. Kronenberg’s laboratory uses genetically manipulated mice to study signaling by the PTH/PTHrP receptor, bone development and the regulation of hematopoiesis by cells of the osteoblast lineage.
Research in the Gardella group is focused on conducts basic research on parathyroid hormone (PTH) and the PTH receptor.
The Eugene Rhee Laboratory is interested in several aspects of renal metabolism, with the goal to understand how alterations in energy metabolism contribute to kidney disease pathogenesis.
The Wein laboratory studies molecular mechanisms controlling osteocyte differentiation and function. Our research focuses on transcriptional control of sclerostin.