Principal Investigators


Darshan DoshiDarshan Doshi, MD
Interventional Cardiologist, Cardiologist and Critical Care Physician
Associate Director, Mass General Chronic Total Occlusion (CTO) Percutaneous Coronary Intervention (PCI) program
Assistant Physician, Mass General Cardiology, Department of Medicine

Bio & Research Interests

Dr. Darshan Doshi is an interventional cardiologist who specializes in complex coronary interventions.

Dr. Doshi received his BA from Columbia University’s Columbia College and his MD from Columbia University’s College of Physicians and Surgeons. He completed his internal medicine residency, and his cardiovascular medicine and interventional cardiology fellowships at the Columbia University Medical Center. Dr. Doshi also underwent additional dedicated training at Columbia in complex and high-risk interventional procedures. He then joined the faculty in the Division of Cardiology at the Massachusetts General Hospital in 2018.

Dr. Doshi also holds an MS in patient-oriented research from Columbia University’s Mailman School of Public Health with a research interest focused on clinical trials evaluating novel cardiovascular devices and therapeutics in interventional cardiology. He has authored several original manuscripts in translational and clinical cardiovascular medicine, and has published in the New England Journal of MedicineLancetJournal of the American College of Cardiology and Circulation, among many others.

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Staff

  • Haley Cerretani (CRC)


Douglas E. Drachman, MDDouglas E. Drachman, MD

Interventional Cardiologist
Director, Cardiovascular Fellowship Program
Director, Interventional Cardiology Fellowship Program

Bio & Research Interests

Dr. Douglas Drachman is an interventional cardiologist whose primary interests include education, research and management of patients with advanced coronary and peripheral vascular disease. Dr. Drachman's research focus is on locally delivered therapeutics, including the development of drug-eluting stent platforms and the evaluation of catheter-based intramyocardial stem cell delivery for therapeutic angiogenesis.

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Sammy Elmariah, MD, MPHSammy Elmariah, MD, MPH
Interventional Cardiologist, Internist
Director, Interventional Cardiology Research


Bio & Research Interests

Dr. Elmariah's research focuses on the prediction and optimization of clinical outcomes of patients with aortic stenosis and after transcatheter aortic valve replacement. Aortic valve stenosis is a disorder predominantly affecting the elderly and characterized by severe narrowing of the aortic valve, the doorway through which blood exits the heart. Aortic stenosis ultimately leads to heart failure and death. Surgical or transcatheter replacement of the valve cures the valve obstruction, but valve replacement is routinely reserved until compensatory mechanisms within the heart have failed. For many patients, this point is too late. Despite valve replacement, damage to the heart muscle may be permanent, resulting in persistent symptoms and increased risk for death. Methods capable of identifying early stages of irreversible heart injury due to aortic valve stenosis are needed in order to help optimize the timing of surgery.

The long-term goal of Dr. Elmariah's work is to identify novel blood markers using novel proteomic and metabolomic profiling techniques that predict heart recovery after valve surgery. Dr. Elmariah anticipates that such measures will help physicians optimize the timing of aortic valve replacement in order to maximize the likelihood that surgery will improve their patients’ symptoms and prolong their lives. Additionally, the type of heart injury that occurs with aortic stenosis also occurs with high blood pressure, diabetes, and several other diseases. Findings from his research have the potential to improve the quality of care for many of these diseases as well.

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Staff

  • Paris Jamiel (PM)
  • Alexandra Selberg (CRC)
  • Matthew Cannata (CRC)
  • Lina Fu, RN (research nurse)
  • Maureen Daher, RN (research nurse)
  • Ritvik Kandanelly (statistician)
  • Devavrat Bapat (statistician)


Michael Fifer, MDMichael Fifer, MD
Clinical Cardiologist, Interventional Cardiologist, Internist
Co-director, Hypertrophic Cardiomyopathy Program



Bio & Research Interests

Michael A. Fifer, MD, directs the Cardiac Cath Lab, Interventional Cardiology Associates and the Hypertrophic Cardiomyopathy Program at the Massachusetts General Hospital Heart Center.

Dr. Fifer received his undergraduate degree summa cum laude from Harvard College and completed his medical degree at Harvard Medical School. Following his internship and residency at Massachusetts General Hospital, he completed his subspecialty fellowship in cardiovascular diseases at Brigham and Women's Hospital. Dr. Fifer joined the faculty of Harvard Medical School in 1984 and is currently a professor of medicine in the Cardiology Division at Massachusetts General Hospital where he is co-director, with Dr. Gus J. Vlahakes, of the Hypertrophic Cardiomyopathy Program, and director of Interventional Cardiology Associates. Dr. Fifer also maintains a general cardiology practice. 

Dr. Fifer's research focuses on hypertrophic cardiomyopathy. He has been a pioneer in the use of alcohol septal ablation, an innovative procedure for patients with the obstructive form of hypertrophic cardiomyopathy. The research arm of the program is currently conducting translational and clinical studies aimed at elucidating the pathophysiologic mechanism of the disease and discovering new treatments.

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Staff

  • John Cadigan (CRC)
  • Cara Berg (CRC)


Joseph Garasic, MDJoseph Garasic, MD
Interventional Cardiologist, Cardiologist
Director, Peripheral Vascular Intervention
Medical Director, Cardiac Access Unit


Bio & Research Interests

Dr. Garasic was born in Chicago, IL and has lived in Boston since 1986. He is a Summa Cum Laude graduate of Boston University School of Medicine, and completed his Internal Medicine Residency, Fellowship in Cardiovascular Disease and Advanced Fellowship training in Interventional Cardiology and Vascular Medicine and Intervention all at Brigham and Women's Hospital/Harvard Medical School in Boston. He has been on staff and the director of Peripheral Vascular Intervention within the Cardiology Division at Massachusetts General Hospital since 2001. Dr. Garasic is the medical director of the Cardiac Interventional Unit at Mass General, is a member of the cardiac catheterization staff and the section of Vascular Medicine. He is co-director of the Vascular Diagnostic and Intervention Fellowship within Cardiology at Mass General. His area of research interest involves clinical investigations of renovascular disease and carotid vascular disease, as well as the discovery of novel endovascular procedures, and the novel use of existing endovascular devices. His clinical practice involves the management of patients with complex and multi-segmental vascular disease. His primary office practice is located on the Mass General main campus, and he also attends a general cardiology outreach clinic in Nantucket, MA.

Dr. Garasic and his wife reside locally in Boston.

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Staff

  • Haley Cerretani (CRC)


Ignacio Inglessis, MDIgnacio Inglessis, MD
Interventional Cardiologist, Cardiologist
Director, Structural Heart Disease Program


Bio & Research Interests
Ignacio Inglessis, MD, is an assistant professor in Medicine at Harvard Medical School and director of the Structural Heart Disease Program at Massachusetts General Hospital. Dr. Inglessis is an active clinical consultant in all aspects of interventional cardiology, including transcatheter therapy for valvular, complex coronary and adult congenital heart disease.

Dr. Inglessis has published more than 60 manuscripts and has co-authored 10 book chapters in the field of interventional cardiology for complex coronary and structural heart disease

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Staff

  • Preeti Paul (CRC)
  • Matt Covello (CRC)
  • Lina Fu, RN (research nurse)
  • Maureen Daher, RN (research nurse)


Farouc Jaffer, MD, PhDFarouc Jaffer, MD, PhD
Interventional Cardiologist, Cardiologist
Director, Coronary Intervention, Massachusetts General Hospital
Director, Mass General Chronic Total Occlusion (CTO) Percutaneous Coronary Intervention (PCI) program
Associate Physician, Mass General Cardiology, Department of Medicine

Bio & Research Interests

Dr. Farouc Jaffer graduated from Stanford University in 1990 with a B.S. in mathematical and computational sciences, and received an MD and PhD in biophysics from the University of Pennsylvania of Medicine in 1996. He completed a residency in internal medicine at the Brigham and Women's Hospital, followed by a fellowship in cardiovascular medicine and interventional cardiology at Massachusetts General Hospital. In 2003, he joined the Cardiology Division as faculty.

Dr. Jaffer is currently an associate professor of medicine at Harvard Medical School and an attending interventional cardiologist at Massachusetts General Hospital. He is director of coronary intervention and director of the Chronic Total Occlusion (CTO) PCI Program at Massachusetts General Hospital. Mass General is a leading center for treating the most complex coronary blockages, such as CTO. Many patients, previously without options, have successfully underwent CTO PCI, and have experienced marked reductions in angina (chest pain) and shortness of breath.

Dr. Jaffer is also a principal investigator in the Mass General Cardiovascular Research Center where his NIH-funded laboratory develops novel molecular imaging approaches to image high-risk plaques and blood clots, to better prevent heart attacks, strokes and venous blood clots.

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Staff

  • Amanda DeGraaf (CRC)


IK Jang, MD, PhDIK Jang, MD, PhD
Interventional Cardiologist, Cardiologist
Director, Clinical Trials Program


Bio & Research Interests

Dr. Jang came to Massachusetts General Hospital in 1987 from Leuven University in Belgium, where he has completed his residency in medicine and fellowship in cardiology. He also successfully defended his doctorate thesis at the same university. After his advanced fellowship in cardiology at Mass General, he joined the staff and is currently working as a physician and an interventional cardiologist in the Cardiology Division. He holds currently an academic title of professor of medicine at Harvard Medical School.

A recipient of the Mass General Brigham in Excellence Award for Research in 2000 and for leadership in 2006, his research roster is extensive and is focused on acute coronary syndromes including acute myocardial infarction. His earlier research focused on pharmacology and physiology of thrombosis and thrombolysis. In 1994 he extended his interests to clinical studies. Since founding the Coronary Clinical Trial Group within the Cardiac Unit in 1995, he has conducted numerous clinical studies. He also led Clinical Research Office of the Cardiology Division between 2003 and 2006. He is currently the director of the Cardiology Laboratory for Integrative Physiology and Imaging (CLIPI).

For the last eleven years he has pioneered the application of intravascular Optical Coherence Tomography (OCT) to patients to better characterize vulnerable plaque and to understand the mechanisms of plaque rupture. Dr. Jang has been invited to lectures at numerous national and international meetings. His publications number more than 200. 

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Staff

  • Iris McNulty, RN (Lab Manager)


Dhaval Kolte, MD, PhD, MBBS

Interventional Cardiologist, Cardiologist, Clinical Researcher
Instructor in Medicine, Harvard Medical School

Bio & Research Interests


Igor Palacios, MDIgor Palacios, MD
Cardiologist, Interventional Cardiologist
Director, Knight Catheterization Laboratory


Bio & Research Interests

Dr. Igor F. Palacios is a nationally and internationally recognized expert in the field of interventional cardiology. He is the director of interventional cardiology.

Dr. Palacios was born in Caracas, Venezuela. After receiving a medical surgeon degree with Magna cum laude honors in 1969, from the Central University of Venezuela, Caracas. Dr. Palacios completed his initial training program at the University Hospital in Caracas, before moving to Massachusetts General Hospital, Boston, MA, USA, to qualify as cardiologist under Professor Edgar Haber in 1974. In 1990, he was appointed director of the Interventional Cardiology Program of the Massachusetts General Hospital.

Dr. Palacios is an internationally recognized expert in the field of interventional cardiology and is a pioneer in the field of percutaneous interventions for structural heart disease. He is member of the editorial board of several peer-reviewed journals in cardiology and has received several awards for distinguished service to medicine and the community in Venezuela, Latin America, and the United States. In 1999, his home country awarded him the Gran Cordon del Libertador ("grand rope of the Liberator") which is the highest honor awarded by the Republic of Venezuela.

In 1997, Dr. Palacios received the Clinician of the Year award; and has been recognized as one of the Best Doctors in the United States by Woodward/White, Inc. for over 10 years; and is included in the U.S. Registry of Who is Who of Outstanding Americans.

Dr. Palacios is a founding member of the Latin American Society for Interventional Cardiology and has made many contributions to Latin American medicine including teaching and lecture presentations. He was also instrumental in helping to establish multi-center clinical trials focusing on interventional cardiology throughout Latin America. He has been a mentor and promoter of more than 25 cardiologists who have become leaders of interventional cardiology in several leading institutions in the USA and abroad. He has published extensively, authoring over 250 papers and 24 book chapters.

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Staff

  • Kahalil Abdurahman (CRC)
  • John Cadigan (CRC)
  • Lina Fu, RN (research nurse)
  • Maureen Daher, RN (research nurse)


Kenneth Rosenfield, MDKenneth Rosenfield, MD

Interventional Cardiologist, Cardiologist
Section Head, Vascular Medicine and Intervention
Chairman, STEMI & Acute MI Quality Improvement Committee

Bio & Research Interests

Kenneth Rosenfield, MD, is the section head for vascular medicine and intervention and chairs the Acute Myocardial Infarction(STEMI) Committee for the cardiac cath lab. He is a national leader in treatment of carotid, kidney and leg artery disease.

Dr. Rosenfield is the section head for vascular medicine and intervention, who specializes in complex cardiac and vascular interventions and directs the program for treatment of acute myocardial infarction (STEMI) in the cardiac catheterization laboratories. He has spearheaded the development of less-invasive therapies for patients with coronary and vascular disease, both at Mass General and nationally, including treatment of carotid, kidney and leg artery narrowing using stents and other novel devices.

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Rahul Sakhuja, MDRahul Sakhuja, MD
Interventional Cardiologist, Cardiologist



Bio & Research Interests

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Staff

  • Olja Rapaic (CRC)
  • Lina Fu, RN (research nurse)
  • Maureen Daher, RN (research nurse)


Robert Schainfeld, DORobert Schainfeld, DO

Internist
Associate Director, Vascular Medicine



Bio & Research Interests


Dr. WeinbergIdo Weinberg, MD

Vascular Medicine Specialist
Director, Vascular Medicine Fellowship


Bio & Research Interests

Dr. Weinberg received his medical degree and completed his internal medicine training at the Hadassah Hebrew University School of Medicine. He then completed his Vascular Medicine Fellowship at the Massachusetts General Hospital and is board certified in vascular medicine (American Board of Vascular Medicine). His on-going research focuses on venous thromboembolic disease and manifestations of arterial disease. He is assistant professor of medicine at Harvard Medical School. Dr. Weinberg is the fellowship director of the Vascular Medicine Fellowship program at Massachusetts General Hospital. He is also co-medical director of the Anticoagulation Management Services at Mass General as well as medical director of VASCORE, the Ultrasound Core Laboratory. Dr. Weinberg is founder and editor-in-chief of Angiologist.com, the only online portal for vascular medicine.

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Research Staff

Kahalil AbdurahmanKahalil Abdurahman
Clinical Research Coordinator
Team: Palacios/Valve



Bio

Abdurahman is a graduate of the University of Damascus medical school in Syria. Before joining our team, he was a research intern in translational colon cancer at the University of Chicago. He also volunteered at Advocate Masonic hospital. Abdurahman is working on several industry-sponsored trials in interventional cardiology. In his free time, he enjoys photography, cooking and soccer.


Devavrat BapatDevavrat Bapat
Statistician
Team: Elmariah/Valve



Bio

Devavrat Bapat graduated from Illinois Institute of Technology (Chicago) with a master’s degree in information technology where he specialized in data management. He has experience with databases in various domains including finance, automation and health care. Besides his work, he is passionate about drama, music, hiking, swimming and spicy foods!


Cara BergCara Berg
Clinical Research Coordinator
Team: Fifer 



Bio

Cara Berg graduated from UMass, Amherst in 2018 with her bachelor’s degree in biology. After graduation, Cara worked for 1.5 years as a clinical care technician in the Tufts Medical Center Surgical ICU. Cara now works in the Mass General Division of Cardiology where she coordinates several studies aimed at understanding and managing hypertrophic cardiomyopathy. Outside of work, Cara enjoys hiking, skiing and exploring Boston.


John CadiganJohn Cadigan
Clinical Research Coordinator
Team: Fifer/Palacios/Valve



Bio

Since graduating from Boston College, John (Jack) Cadigan has been working as a research coordinator for Dr. Fifer and Dr. Palacios. Jack has always wanted to pursue a career in medicine and has future hopes of attending medical school. In his free time, Jack loves to play golf and watch football. 


Matthew CannataMatthew Cannata
Clinical Research Coordinator 
Team: Elmariah/Valve



Bio

Matt Cannata is a graduate of Worcester Polytechnic Institute where he studied biomedical engineering. While at WPI, he researched the development of fibrin and collagen-based micro-threads along with a novel collagen-based device for ligament repair. Matt has since shifted his focus from engineering to pursuing a career in medicine. In his spare time, he loves to train for powerlifting, cook, learn new things and spend time with his friends, family and pet chinchilla.


Haley CerretaniHaley Cerretani
Clinical Research Coordinator
Team: Doshi/Garasic



Bio

Haley Cerretani, a Boston University graduate with a degree in health sciences and a minor in Spanish, has recently joined the Interventional Cardiology Research Team after spending time with the Orthopedic Oncology Team here at Mass General! Her background lies mostly in animal research, centered upon a canary lab studying speech patterns and intentional neural lesioning. Outside of research, she is an avid functional fitness goer. If she’s not in the gym, she’s likely cooking, baking, out with friends or taking care of her once-stray orange tabby cat named Freddie (named after the lead singer in Queen).


Matthew CovelloMatthew Covello
Clinical Research Coordinator
Team: Inglessis/Valve



Bio

Matt Covello, one of our research coordinators, graduated from Tufts University, where he got his BS in biology, volunteered as an EMT-B for Tufts Emergency Medical Services and worked in the Mass General Emergency Department. Matt now helps to manage structural heart device trials on the Valve Team with Dr. Inglessis, focusing on transcatheter aortic valve replacements, patent foramen ovale closures and mitral valve repairs and replacements. Outside of work, his hobbies include golfing, fly fishing and flying airplanes as a certified private pilot.


Maureen Daher, RN
Research Nurse
Team: Valve

Amanda DeGraafAmanda DeGraaf
Clinical Research Coordinator
Team: Jaffer



Bio

Amanda DeGraaf graduated from Lehigh University with a BS in behavioral neuroscience. While in college, she researched how to better enable stroke survivors to relearn language and motor control by reopening the critical period of learning. During her time at Mass General, she has worked as a research coordinator on investigational device trials for patients undergoing high-risk percutaneous coronary interventions (PCI). Outside of work, she loves to cook and is always on the hunt for new recipes to try!


Lina Fu, RN
Research Nurse
Team: Valve

Bio

Lina Fu, RN. BSN. graduate from Northeastern University with summa cumme laude and academic excellence award and received clinical research certificate from Boston College. As an experience nurse working with patients with chronic neurological conditions, such as Multiple Sclerosis, Epilepsy, Parkinson’s Disease, Migraine headaches, etc., she joined the clinical research team at MGH since 2014 with deep commitment to patient advocacy delivering quality, compassionate, evidence-based care in the clinical research environment. She loves to work with people, enjoy the collaboration with her fellow clinical research team members, clinical health providers and patients to explore the best available treatment options for in clinical research. Outside of work, she loves to spend time with family and friends, reading, volunteering in local non-profit organizations.



NurAlima Grandison

Program Manager


Paris Jamiel Paris Jamiel 
Project Manager 
Team: Elmariah/Valve/Interventional Cardiology Program



Bio

Paris Jamiel is currently the project manager for Dr. Elmariah. She works closely with both his personal research team and the Interventional Cardiology Research Program as a whole. Prior to her role as a project manager, Paris was a clinical research coordinator in the Cardiology department at Mass General. She received her BS in microbiology with an additional focus in biomedical biosystems from the University of Massachusetts, Amherst. When she’s not at Mass General, you can find Paris at the barre studio, cooking or spending time with her many siblings.


Ritvik KandanellyRitvik Kandanelly
Statistician
Team: Elmariah/Valve



Bio

Ritvik Kandanelly finished his master of science degree in health data analytics from Northeastern University. He is a firm believer that data analytics has the power to influence the health of many patients, and data-driven decisions are the future of health care. He is also a PhD biostatistics enthusiast.



Julia LarsonJulia Larson

Program Coordinator




Bio

Julia Larson is the program coordinator for the Heart Center Clinical Research Program. This program includes all branches of our cardiology research, including interventional cardiology. She grew up in NY, but since graduating with her bachelor’s from Stonehill College, she has been living in Boston. Some of her favorite things include traveling and being outside whenever possible (especially hiking in the White Mountains, snowboarding, running/exercising). Soccer has always been a huge part of Julia’s life. In her free time, she currently volunteers as a coach with a non-profit called Soccer Without Borders.


Iris McNulty, RN
Mass General Coronary OCT Lab Manager
Team: Jang

Bio

Iris McNulty was excited to return to Mass General to work with Dr. Jang after a five-year hiatus. She began her career at MGH in 1995 after receiving a bachelor’s degree in Anthropology from Brown University. While working at Mass General she pursued her interest in nursing, obtaining a BSN from Simmons College. Her interests ultimately led her to a role as a clinical research nurse for more than a decade. She has significant experience working on Optical Coherence Tomography (OCT) clinical trials and worked with Dr. Jang during the inception of the Mass General OCT Registry, a multi-center, international registry of almost 3,000 patients with up to five years of prospective follow-up. Since her return to Mass General, she has continued to help Dr. Jang expand his OCT research.


Preeti PaulPreeti Paul
Clinical Research Coordinator
Team: Inglessis/Valve



Bio

Preeti Paul’s love for science led her to complete a master's degree in biochemistry. Her professional journey prior to clinical research has included roles in quality Assurance, device training and scientific services in the diagnostics industry. Currently, Preeti helps in the management of all TAVR trials for Dr. Inglessis. She plans to continue working in the field of clinical research and contribute towards developing evidence-based care. The most exciting adventure of her life has been motherhood, as a mom of two. In her free time, she loves to travel and advocate for a more sustainable future.


Olja RapaicOlja Rapaic
Clinical Research Coordinator
Team: Sakhuja/Valve



Bio

Olja Rapaic started working as a CRC in the Heart Center after graduating from UMass Amherst with a BS in kinesiology. Olja is currently also pursuing her goal of attending medical school. Outside of work, she enjoys rollerblading, playing basketball with friends and going to local music events.


Alexandra SelbergAlexandra Selberg
Clinical Research Coordinator 
Team: Elmariah/Valve



Bio

Alexandra Selberg is a graduate of Columbia University and the Courtauld Institute, University of London. While at Columbia, she volunteered in the Pediatric Emergency Department as a research assistant with a focus on machine learning for point-of-care ultrasounds, improving pediatric diagnostic testing and adolescent sexual health. As part of the Valve Team, Alexandra manages investigational device trials for structural heart disease, as well as PI-initiated multi-omics studies. She is an avid runner and member of the Dashing Whippets Running Team.