Short bursts of physical exercise induce changes in the body’s levels of metabolites that correlate to, and may help gauge, an individual’s cardiometabolic, cardiovascular and long-term health.
For more than 100 years, researchers at the Massachusetts General Hospital Corrigan Minehan Heart Center have conducted groundbreaking research and clinical trials to diagnose, treat and prevent heart disease.
Working to End Heart Disease
From pioneering technologies that monitor heart failure patients at home to discovering a master cell that has shown a promising ability to repair damaged heart tissue, Corrigan Minehan Heart Center research has led to major advances in cardiovascular medicine.
Our research focuses on:
- Understanding what leads to heart disorders
- Identifying new treatments for heart disease
- Repairing damaged hearts and blood vessels
- Uncovering new minimally invasive treatment options
The Corrigan Minehan Heart Center conducts the full range of research—from basic investigation that improves our understanding of the causes of cardiovascular disease to translational research that brings new discoveries to the bedside for the benefit of patients.
Breakthroughs at the Cardiovascular Research CenterWith more than 35,000 square feet dedicated to investigating heart disease, the Cardiovascular Research Center (CVRC) is the major research arm of the Corrigan Minehan Heart Center. CVRC breakthroughs have led to new treatments for heart disease and related disorders such as diabetes. Learn more about the Cardiovascular Research Center.
Cardiac Resynchronization Therapy
We are developing new technologies to monitor heart failure patients remotely and improve the efficiency of cardiac devices used to treat heart failure.
Preventing Heart Disease
Understanding the genetics of heart disease means that we can identify heart disease patients earlier and help prevent this condition in their children. We are also working to prevent heart disease in women from low-income Boston neighborhoods.
Learn more about the Cardiovascular Disease Prevention Center
Learn more about the Corrigan Women’s Heart Health Program
Adult Congenital Heart Disease
At the Corrigan Minehan Heart Center, we are investigating new devices to treat congenital heart defects. We also helped found a worldwide registry that enables researchers to conduct long-term studies of adults who have grown up with this condition.
Learn more about the Adult Congenital Heart Disease Program
Our research focuses on preventing cardiac events in professional athletes and highly active patients, from college students to seniors.
Coronary Artery Disease
Our studies of stem cells and genetic risk factors help us understand why people develop heart disease. We are also leading a major clinical trial to learn how type II diabetes impacts heart disease.
Heart Failure and Transplant
Mass General is one of a few select hospitals in the nation to receive a National Institutes of Health grant to study heart transplantation. Our research explores improving the success of heart transplants in patients who are at high risk of organ rejection. We are also part of a network of advanced centers for heart failure research created by the National Heart, Lung, and Blood Institute.
Corrigan Minehan Heart Center investigators are evaluating a unique, minimally invasive procedure called transcatheter aortic valve replacement as a treatment option for patients with severe aortic valve stenosis who are not candidates for open-heart surgery.
We are discovering new ways to diagnose heart attacks within minutes, instead of hours, and are uncovering the genetic makeup of hypertrophic cardiomyopathy.
Thoracic Aortic Disease
Researchers at the Corrigan Minehan Heart Center helped found an international registry of patients with thoracic aortic disease that tracks thousands of cases and guides treatment direction to physicians worldwide.
- Press Release
- Nov | 11 | 2020
New research by investigators at Massachusetts General Hospital (MGH) reveals considerable uncertainty in how to care for patients with a certain type of heart attack.
- Press Release
- Nov | 10 | 2020
Study reveals reveals women with premature menopause often exhibit certain blood cell changes that elevate their risk of developing coronary artery disease.
- Oct | 9 | 2020
Mass General and Newton-Wellesley Hospital staff have been working together for the past eight months to ensure a safe, efficient and thoughtful transition plan for the more than 600 anticoagulation patients who will now receive their care at the MGH AMS Clinic.
- Staff Story
- Oct | 6 | 2020
When asked about his experience in the Cardiovascular Disease Fellowship Program at Massachusetts General Hospital, second-year fellow and aspiring academic cardiac electrophysiologist Daniel Pipilas, MD, says “even in this short time, there are a few people who really stick out as great mentors.”
- Press Release
- Oct | 6 | 2020
Genetic testing for a lipoprotein linked to cardiovascular risk is as effective as blood work, study shows
Elevated levels of a little-known lipoprotein in the blood that may put people at high risk of cardiovascular disease can be as accurately detected by genetic testing as by conventional laboratory measurement.