For more than 100 years, researchers at the Massachusetts General Hospital Corrigan Minehan Heart Center have conducted groundbreaking research and clinical trials to diagnose, treat and prevent heart disease.

Working to End Heart Disease

From pioneering technologies that monitor heart failure patients at home to discovering a master cell that has shown a promising ability to repair damaged heart tissue, Corrigan Minehan Heart Center research has led to major advances in cardiovascular medicine.

Our research focuses on:

  • Understanding what leads to heart disorders
  • Identifying new treatments for heart disease
  • Repairing damaged hearts and blood vessels
  • Uncovering new minimally invasive treatment options

The Corrigan Minehan Heart Center conducts the full range of research—from basic investigation that improves our understanding of the causes of cardiovascular disease to translational research that brings new discoveries to the bedside for the benefit of patients.

Breakthroughs at the Cardiovascular Research Center

With more than 35,000 square feet dedicated to investigating heart disease, the Cardiovascular Research Center (CVRC) is the major research arm of the Corrigan Minehan Heart Center. CVRC breakthroughs have led to new treatments for heart disease and related disorders such as diabetes. Learn more about the Cardiovascular Research Center.

Cardiac Arrhythmia

Mass General researchers are studying the genetic basis of atrial fibrillation and defining new treatment approaches, such as catheter ablation and left atrial appendage exclusion, for this condition.

Learn more about the Telemachus & Irene Demoulas Family Foundation Center for Cardiac Arrhythmias >

Cardiac Resynchronization Therapy

We are developing new technologies to monitor heart failure patients remotely and improve the efficiency of cardiac devices used to treat heart failure.

Learn more about the Cardiac Resynchronization Therapy Program

Preventing Heart Disease

Understanding the genetics of heart disease means that we can identify heart disease patients earlier and help prevent this condition in their children. We are also working to prevent heart disease in women from low-income Boston neighborhoods.

Learn more about the Cardiovascular Disease Prevention Center

Learn more about the Corrigan Women’s Heart Health Program

Adult Congenital Heart Disease

At the Corrigan Minehan Heart Center, we are investigating new devices to treat congenital heart defects. We also helped found a worldwide registry that enables researchers to conduct long-term studies of adults who have grown up with this condition.

Learn more about the Adult Congenital Heart Disease Program

Cardiovascular Performance

Our research focuses on preventing cardiac events in professional athletes and highly active patients, from college students to seniors.

Learn more about the Cardiovascular Performance Program

Coronary Artery Disease

Our studies of stem cells and genetic risk factors help us understand why people develop heart disease. We are also leading a major clinical trial to learn how type II diabetes impacts heart disease.

Learn more about the Complex Coronary Intervention Program

Heart Failure and Transplant

Mass General is one of a few select hospitals in the nation to receive a National Institutes of Health grant to study heart transplantation. Our research explores improving the success of heart transplants in patients who are at high risk of organ rejection. We are also part of a network of advanced centers for heart failure research created by the National Heart, Lung, and Blood Institute.

Learn more about the Heart Failure and Cardiac Transplant Program

Heart Valve

Corrigan Minehan Heart Center investigators are evaluating a unique, minimally invasive procedure called transcatheter aortic valve replacement as a treatment option for patients with severe aortic valve stenosis who are not candidates for open-heart surgery.

Learn more about the Heart Valve Program

Hypertrophic Cardiomyopathy

We are discovering new ways to diagnose heart attacks within minutes, instead of hours, and are uncovering the genetic makeup of hypertrophic cardiomyopathy.

Learn more about the Hypertrophic Cardiomyopathy Program

Thoracic Aortic Disease

Researchers at the Corrigan Minehan Heart Center helped found an international registry of patients with thoracic aortic disease that tracks thousands of cases and guides treatment direction to physicians worldwide.

Learn more about the Thoracic Aortic Center