Contact Information

Edward T. Ryan, MD

Jackson 504
55 Fruit Street
Boston, MA  02114

Phone: 617-726-6175
Fax: 617-726-7416

Email: etryan@mgh.harvard.edu

Dr. Ryan's Clinical Profile
For clinical issues please call: 617-724-6454

Kyle Kennedy
Administrative Coordinator

Explore This Laboratory

    About Us

    Our research focuses on host-bacterial pathogen interactions and immune responses, with a particular focus on enteric infections and the development of vaccines protective against enteric infections, and development of diagnostic assays. Specific focus areas include Vibrio cholerae, the cause of cholera, and Salmonella enterica, the causes of typhoid and paratyphoid fever. We work in collaborative efforts with researchers at the International Centre for Diarrhoeal Disease Research in Dhaka Bangladesh (ICDDR,B).

    Research Projects

    Immune responses during cholera

    In a collaborative effort with researchers at the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh (ICDDR,B), we are evaluating immune responses in humans infected with Vibrio cholerae, the cause of cholera. V. cholerae is endemic in over 50 countries, infects approximately 3-5 million individuals globally, and results in the death of approximately 100,000 individuals each year. Individuals most affected by cholera are those most impoverished, especially those lacking safe water and sanitary facilities, as well as individuals displaced by war, famine, disasters, and conflict. Cholera can be explosively epidemic, and the global burden of cholera may well increase with climate change, severe weather events, and increasing urbanization. V. cholerae is a human-restricted infection, and current cholera vaccines provide relatively short-term protection against disease. The mediators of protective immunity against cholera are poorly understood. To address this, we are applying a number of high throughput and platform technologies to assess innate and adaptive immune responses in humans with cholera and their household contacts, stratifying responses in the latter by subsequent protection from disease, and comparing responses in the former to those that occur in recipients of current cholera vaccines. The goal of these studies is to identify the mediators of protection against cholera, in order to advance improved prevention strategies, as well as to advance vaccine development and deployment.

    Host-pathogen interactions during typhoid fever

    In a collaborative effort with researchers at the International Centre for Diarrhoeal Disease Research in Dhaka, Bangladesh (ICDDR,B), we are evaluating host-pathogen interactions and immune responses in humans infected with Salmonella enterica serotype Typhi (the cause of typhoid fever) and S. Paratyphi (the cause of paratyphoid fever). Together, S. Typhi and S. Paratyphi cause approximately 20 million cases of enteric fever world-wide, resulting in approximately 200,000 deaths each year. Most of these deaths occur in impoverished children and young adults. Although usually caused by S. Typhi, one in four cases of enteric fever is caused by S. Paratyphi in many areas of the world. S. Typhi and S. Paratyphi are particularly common among urban residents in informal settlements and slums, although any individual lacking safe water and sanitary facilities is at risk of infection. Vaccines against S. Typhi provide only 50-60% protection against disease for 2-5 years, and, at present, there is no commercially available vaccine against S. Paratyphi. There is also no good point-of-care test to diagnose individuals with enteric fever, and S. Typhi and S. Paratyphi are becoming increasingly resistant to antimicrobial agents.To address this, we are evaluating host-pathogen interactions directly in humans infected with S. Typhi and S. Paratyphi. We are applying a number of technologies to evaluate innate and adaptive immune responses directly in humans infected with S. Typhi and S. Paratyphi in Bangladesh, and we are evaluating bacterial responses in humans during these human-restricted infections. The goal of these studies is to develop improved diagnostic assays, antimicrobial agents, and preventative strategies against these infections.

    Immunization approaches for enteric infection

    A fundamental challenge facing many enteric and mucosal vaccines is their inability to induce long-term protective immunity. Many of these vaccines may not be prominent inducers of memory cells, which play critical roles in mediating long-term protection against disease. Using our analysis of memory B and T cell induction during wild-type human enteric infection in Bangladesh, we are evaluating the ability of a number of vaccination approaches and strategies to induce long-term memory responses protective against mucosal and enteric infections, including development of enteric conjugate vaccines, and analysis of oral-transcutaneous prime-boosting approaches.

    Global TravEpiNet (GTEN)

    To extend our analysis of infections associated with living in, traveling through, or immigrating from resource-limited areas, we also work with the U.S. Centers for Disease Control and Prevention through the GTEN (Global TravEpiNet; Global Travelers’ Epidemiology Network) Program. GTEN’s mission is to advance the health of American residents who travel internationally, as well as to lessen the likelihood of disease importation into home communities. GTEN-related resources are available at Heading Home Healthy. Through this program, we have been able to address COVID-19, an illness introduced into U.S. populations through travel. Our efforts have focused on understanding diagnostic assays and transmission dynamics to assist in control measures. We have assessed immune responses during SARS-CoV-2 infection, including duration and cross reactivity with other coronaviridae, characterized immune responses during naturally acquired disease to inform vaccine development, and phylogenetically typed viral strains to assess introduction and transmission of SARS-CoV-2 at population levels.

    Publications

    References
    1. Knowledge, attitudes and practices regarding the use of mobile travel health apps.
      Machoko MMP, Dong Y, Grozdani A, Hong H, Oliver E, Hyle EP, Ryan ET, Colubri A, LaRocque RC. J Travel Med. 2023 Jul 06. PMID: 37410376.
    2. Development of Shigella conjugate vaccines targeting Shigella flexneri 2a and S. flexneri 3a using a simple platform-approach conjugation by squaric acid chemistry.
      Kelly M, Mandlik A, Charles RC, Verma S, Calderwood SB, Leung DT, Biswas R, Islam K, Kamruzzaman M, Chowdhury F, Khanam F, Vann WF, Khan AI, Bhuiyan TR, Qadri F, Vortherms AR, Kaminski R, Kovác P, Xu P, Ryan ET. Vaccine. 2023 07 31; 41(34):4967-4977. PMID: 37400283.
    3. Mass photometry: A powerful tool for carbohydrates-proteins conjugation monitoring and glycoconjugates molecular mass determination.
      Wu D, Xu P, Kelly M, Ryan ET, Kovác P, Piszczek G. Glycoconj J. 2023 08; 40(4):401-412. PMID: 37392327.
    4. Shigella O-specific polysaccharide functional IgA responses mediate protection against shigella infection in an endemic high-burden setting.
      Bernshtein B, Kelly M, Cizmeci D, Zhiteneva JA, Macvicar R, Kamruzzaman M, Bhuiyan TR, Chowdhury F, Khan AI, Qadri F, Charles RC, Xu P, Kovác P, Kaminski RW, Alter G, Ryan ET. bioRxiv. 2023 May 05. PMID: 37205407.
    5. Intrinsic Resistance to Colistin in the Genus Hafnia.
      Turbett SE, Bronson RA, Worby CJ, McGrath GEG, Hodgkins E, Becker M, Belford B, Kogut L, Oliver E, Ryan ET, LaRocque RC, Earl AM, Pierce VM. J Clin Microbiol. 2023 05 23; 61(5):e0132622. PMID: 37022168.
    6. Predicting Vibrio cholerae infection and symptomatic disease: a systems serology study.
      Wiens KE, Iyer AS, Bhuiyan TR, Lu LL, Cizmeci D, Gorman MJ, Yuan D, Becker RL, Ryan ET, Calderwood SB, LaRocque RC, Chowdhury F, Khan AI, Levine MM, Chen WH, Charles RC, Azman AS, Qadri F, Alter G, Harris JB. Lancet Microbe. 2023 04; 4(4):e228-e235. PMID: 36907197.
    7. Distinguishing Severe Acute Respiratory Syndrome Coronavirus 2 Persistence and Reinfection: A Retrospective Cohort Study.
      Turbett SE, Tomkins-Tinch CH, Anahtar MN, Dugdale CM, Hyle EP, Shenoy ES, Shaw B, Egbuonu K, Bowman KA, Zachary KC, Adams GC, Hooper DC, Ryan ET, LaRocque RC, Bassett IV, Triant VA, Siddle KJ, Rosenberg E, Sabeti PC, Schaffner SF, MacInnis BL, Lemieux JE, Charles RC. Clin Infect Dis. 2023 03 04; 76(5):850-860. PMID: 36268576.
    8. Development of a prediction model for the Acquisition of Extended Spectrum Beta-Lactam Resistant Organisms in U.S. international travellers.
      Brown DG, Worby CJ, Pender MA, Brintz BJ, Ryan ET, Sridhar S, Oliver E, Harris JB, Turbett SE, Rao SR, Earl AM, LaRocque RC, Leung DT. J Travel Med. 2023 Mar 02. PMID: 36864572.
    9. Travel-associated extensively drug-resistant typhoid fever: a case series to inform management in non-endemic regions.
      Posen HJ, Wong W, Farrar DS, Campigotto A, Chan T, Barker KR, Hagmann SHF, Ryan ET, LaRocque RC, Earl AM, Worby CJ, Castelli F, Fumadó VP, Britton PN, Libman M, Hamer DH, Morris SK. J Travel Med. 2023 02 18; 30(1). PMID: 35904457.
    10. Long-term sialidase-specific immune responses after natural infection with cholera: Findings from a longitudinal cohort study in Bangladesh.
      Chowdhury F, Akter A, Bhuiyan TR, Biswas R, Firoj MG, Tauheed I, Harris JB, Larocque RC, Ross AG, McMillan NAJ, Charles RC, Ryan ET, Calderwood SB, Qadri F. Front Immunol. 2022; 13:1067737. PMID: 36618409.
    11. Longevity of memory B cells and antibodies, as well as the polarization of effector memory helper T cells, are associated with disease severity in patients with COVID-19 in Bangladesh.
      Akhtar M, Basher SR, Nizam NN, Kamruzzaman M, Khaton F, Banna HA, Kaisar MH, Karmakar PC, Hakim A, Akter A, Ahmed T, Tauheed I, Islam S, Ahmmed F, Mahamud S, Hasnat MA, Sumon MA, Rashed A, Ghosh S, Calderwood SB, Harris JB, Charles RC, LaRocque RC, Ryan ET, Banu S, Shirin T, Chowdhury F, Bhuiyan TR, Qadri F. Front Immunol. 2022; 13:1052374. PMID: 36578502.
    12. Repertoires of SARS-CoV-2 epitopes targeted by antibodies vary according to severity of COVID-19.
      Gregory DJ, Vannier A, Duey AH, Roady TJ, Dzeng RK, Pavlovic MN, Chapin MH, Mukherjee S, Wilmot H, Chronos N, Charles RC, Ryan ET, LaRocque RC, Miller TE, Garcia-Beltran WF, Thierauf JC, Iafrate AJ, Mullenbrock S, Stump MD, Wetzel RK, Polakiewicz RD, Naranbhai V, Poznansky MC. Virulence. 2022 12; 13(1):890-902. PMID: 35587156.
    13. Identifying Recent Cholera Infections Using a Multiplex Bead Serological Assay.
      Jones FK, Bhuiyan TR, Muise RE, Khan AI, Slater DM, Hutt Vater KR, Chowdhury F, Kelly M, Xu P, Kovác P, Biswas R, Kamruzzaman M, Ryan ET, Calderwood SB, LaRocque RC, Lessler J, Charles RC, Leung DT, Qadri F, Harris JB, Azman AS. mBio. 2022 12 20; 13(6):e0190022. PMID: 36286520.
    14. Cholera Vaccine: Recommendations of the Advisory Committee on Immunization Practices, 2022.
      Collins JP, Ryan ET, Wong KK, Daley MF, Ratner AJ, Appiah GD, Sanchez PJ, Gutelius BJ. MMWR Recomm Rep. 2022 09 30; 71(2):1-8. PMID: 36173766.
    15. Vibrio cholerae Isolation from Frozen Vomitus and Stool Samples.
      Dunmire CN, Chac D, Chowdhury F, Khan AI, Bhuiyan TR, LaRocque RC, Akter A, Amin MA, Ryan ET, Qadri F, Weil AA. J Clin Microbiol. 2022 10 19; 60(10):e0108422. PMID: 36169311.
    16. Erratum to: Use of a MAIT-Activating Ligand, 5-OP-RU, as a Mucosal Adjuvant in a Murine Model of Vibrio cholerae O1 Vaccination.
      Jensen O, Trivedi S, Cacioppo JG, Li K, Aubé J, Hale JS, Ryan ET, Leung DT. Pathog Immun. 2022; 7(1):145-146. PMID: 36147447.
    17. Use of a MAIT-Activating Ligand, 5-OP-RU, as a Mucosal Adjuvant in a Murine Model of Vibrio cholerae O1 Vaccination.
      Jensen O, Trivedi S, Li K, Aubé J, Hale JS, Ryan ET, Leung DT. Pathog Immun. 2022; 7(1):122-144. PMID: 36072570.
    18. Systems approach to define humoral correlates of immunity to Shigella.
      Bernshtein B, Ndungo E, Cizmeci D, Xu P, Kovác P, Kelly M, Islam D, Ryan ET, Kotloff KL, Pasetti MF, Alter G. Cell Rep. 2022 08 16; 40(7):111216. PMID: 35977496.
    19. High-risk US International Travelers Seeking Pretravel Consultation During the COVID-19 Pandemic.
      Hyle EP, Le MH, Rao SR, Mulroy NM, Walker AT, Ryan ET, LaRocque RC. Open Forum Infect Dis. 2022 Aug; 9(8):ofac399. PMID: 36000001.
    20. Proteomic analysis of cardiometabolic biomarkers and predictive modeling of severe outcomes in patients hospitalized with COVID-19.
      Schroeder PH, Brenner LN, Kaur V, Cromer SJ, Armstrong K, LaRocque RC, Ryan ET, Meigs JB, Florez JC, Charles RC, Mercader JM, Leong A. Cardiovasc Diabetol. 2022 07 21; 21(1):136. PMID: 35864532.
    21. The Clinical and Economic Impact of Measles-Mumps-Rubella Vaccinations to Prevent Measles Importations From US Pediatric Travelers Returning From Abroad.
      Bangs AC, Gastañaduy P, Neilan AM, Fiebelkorn AP, Walker AT, Rao SR, Ryan ET, LaRocque RC, Walensky RP, Hyle EP. J Pediatric Infect Dis Soc. 2022 Jun 22; 11(6):257-266. PMID: 35333347.
    22. Estimating typhoid incidence from community-based serosurveys: a multicohort study.
      Aiemjoy K, Seidman JC, Saha S, Munira SJ, Islam Sajib MS, Sium SMA, Sarkar A, Alam N, Zahan FN, Kabir MS, Tamrakar D, Vaidya K, Shrestha R, Shakya J, Katuwal N, Shrestha S, Yousafzai MT, Iqbal J, Dehraj IF, Ladak Y, Maria N, Adnan M, Pervaiz S, Carter AS, Longley AT, Fraser C, Ryan ET, Nodoushani A, Fasano A, Leonard MM, Kenyon V, Bogoch II, Jeon HJ, Haselbeck A, Park SE, Zellweger RM, Marks F, Owusu-Dabo E, Adu-Sarkodie Y, Owusu M, Teunis P, Luby SP, Garrett DO, Qamar FN, Saha SK, Charles RC, Andrews JR. Lancet Microbe. 2022 08; 3(8):e578-e587. PMID: 35750069
    23. Mucosal-Associated Invariant T (MAIT) cells are highly activated in duodenal tissue of humans with Vibrio cholerae O1 infection: A preliminary report.
      Bhuiyan TR, Rahman MA, Trivedi S, Afroz T, Al Banna H, Hoq MR, Pop I, Jensen O, Rashu R, Uddin MI, Hossain M, Khan AI, Chowdhury F, Harris JB, Calderwood SB, Ryan ET, Qadri F, Leung DT. PLoS Negl Trop Dis. 2022 05; 16(5):e0010411. PMID: 35551522.
    24. The Effect of Vaccine Type and SARS-CoV-2 Lineage on Commercial SARS-CoV-2 Serologic and Pseudotype Neutralization Assays in mRNA Vaccine Recipients.
      Tolan NV, Sherman AC, Zhou G, Nabel KG, Desjardins M, Melanson S, Kanjilal S, Moheed S, Kupelian J, Kaufman RM, Ryan ET, LaRocque RC, Branda JA, Dighe AS, Abraham J, Baden LR, Charles RC, Turbett SE. Microbiol Spectr. 2022 04 27; 10(2):e0021122. PMID: 35311584.
    25. Virus-like Particle Display of Vibrio choleraeO-Specific Polysaccharide as a Potential Vaccine against Cholera.
      Rashidijahanabad Z, Kelly M, Kamruzzaman M, Qadri F, Bhuiyan TR, McFall-Boegeman H, Wu D, Piszczek G, Xu P, Ryan ET, Huang X. ACS Infect Dis. 2022 03 11; 8(3):574-583. PMID: 35170309.
    26. Seroprevalence of SARS-CoV-2 antibodies in Bangladesh related to novel coronavirus infection.
      Bhuiyan TR, Akhtar M, Akter A, Khaton F, Rahman SIA, Ferdous J, Nazneen A, Sumon SA, Banik KC, Bablu AR, Alamgir ASM, Rahman M, Tony SR, Hossain K, Calderwood SB, Charles RC, Ryan ET, LaRocque RC, Harris JB, Rahman M, Chakraborty N, Rahman M, Arifeen SE, Flora MS, Shirin T, Banu S, Qadri F. IJID Reg. 2022 Mar; 2:198-203. PMID: 35721426.
    27. Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain.
      Nabel KG, Clark SA, Shankar S, Pan J, Clark LE, Yang P, Coscia A, McKay LGA, Varnum HH, Brusic V, Tolan NV, Zhou G, Desjardins M, Turbett SE, Kanjilal S, Sherman AC, Dighe A, LaRocque RC, Ryan ET, Tylek C, Cohen-Solal JF, Darcy AT, Tavella D, Clabbers A, Fan Y, Griffiths A, Correia IR, Seagal J, Baden LR, Charles RC, Abraham J. Science. 2022 01 21; 375(6578):eabl6251. PMID: 34855508.
    28. Evaluation of Candida auris acquisition in US international travellers using a culture-based screening protocol.
      Turbett ISE, Becker DSM, Belford MTB, Kelly RTM, Desrosiers MTL, Oliver RNE, Branda APJA, Walters EM, Walker EAT, LaRocque APR, Ryan ET. J Travel Med. 2022 01 17; 29(1). PMID: 34875080.
    29. Disease characteristics and serological responses in patients with differing severity of COVID-19 infection: A longitudinal cohort study in Dhaka, Bangladesh.
      Akter A, Ahmed T, Tauheed I, Akhtar M, Rahman SIA, Khaton F, Ahmmed F, Ferdous J, Afrad MH, Kawser Z, Hossain M, Khondaker R, Hasnat MA, Sumon MA, Rashed A, Ghosh S, Calderwood SB, Charles RC, Ryan ET, Khatri P, Maecker HT, Obermoser G, Pulendran B, Clemens JD, Banu S, Shirin T, LaRocque RC, Harris JB, Bhuiyan TR, Chowdhury F, Qadri F. PLoS Negl Trop Dis. 2022 01; 16(1):e0010102. PMID: 34982773.
    30. Coronavirus Disease 2019 (COVID-19) Diagnostic Clinical Decision Support: A Pre-Post Implementation Study of CORAL (COvid Risk cALculator).
      Dugdale CM, Rubins DM, Lee H, McCluskey SM, Ryan ET, Kotton CN, Hurtado RM, Ciaranello AL, Barshak MB, McEvoy DS, Nelson SB, Basgoz N, Lazarus JE, Ivers LC, Reedy JL, Hysell KM, Lemieux JE, Heller HM, Dutta S, Albin JS, Brown TS, Miller AL, Calderwood SB, Walensky RP, Zachary KC, Hooper DC, Hyle EP, Shenoy ES. Clin Infect Dis. 2021 12 16; 73(12):2248-2256. PMID: 33564833.
    31. Case 34-2021: A 38-Year-Old Man with Altered Mental Status and New Onset of Seizures.
      Cole AJ, Slutzman JE, Ryan ET, Lev MH, Eng G. N Engl J Med. 2021 Nov 11; 385(20):1894-1902. PMID: 34758256.
    32. Scalable production and immunogenicity of a cholera conjugate vaccine.
      Jeon S, Kelly M, Yun J, Lee B, Park M, Whang Y, Lee C, Halvorsen YD, Verma S, Charles RC, Harris JB, Calderwood SB, Leung DT, Bhuiyan TR, Qadri F, Kamruzzaman M, Cho S, Vann WF, Xu P, Kovác P, Ganapathy R, Lynch J, Ryan ET. Vaccine. 2021 11 16; 39(47):6936-6946. PMID: 34716040
    33. Systemic, Mucosal, and Memory Immune Responses following Cholera.
      Ryan ET, Leung DT, Jensen O, Weil AA, Bhuiyan TR, Khan AI, Chowdhury F, LaRocque RC, Harris JB, Calderwood SB, Qadri F, Charles RC. Trop Med Infect Dis. 2021 Oct 27; 6(4). PMID: 34842841.
    34. A Combination of Metagenomic and Cultivation Approaches Reveals Hypermutator Phenotypes within Vibrio cholerae-Infected Patients.
      Levade I, Khan AI, Chowdhury F, Calderwood SB, Ryan ET, Harris JB, LaRocque RC, Bhuiyan TR, Qadri F, Weil AA, Shapiro BJ. mSystems. 2021 Aug 31; 6(4):e0088921. PMID: 34427503.
    35. Gut Microbiota and Development of Vibrio cholerae-Specific Long-Term Memory B Cells in Adults after Whole-Cell Killed Oral Cholera Vaccine.
      Chac D, Bhuiyan TR, Saha A, Alam MM, Salma U, Jahan N, Chowdhury F, Khan AI, Ryan ET, LaRocque R, Harris JB, Qadri F, Weil AA. Infect Immun. 2021 08 16; 89(9):e0021721. PMID: 34228490.
    36. An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates.
      Zabaleta N, Dai W, Bhatt U, Hérate C, Maisonnasse P, Chichester JA, Sanmiguel J, Estelien R, Michalson KT, Diop C, Maciorowski D, Dereuddre-Bosquet N, Cavarelli M, Gallouët AS, Naninck T, Kahlaoui N, Lemaitre J, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, LaRocque RC, Charles RC, Li D, Kim M, Sheridan A, Storm N, Johnson RI, Feldman J, Hauser BM, Contreras V, Marlin R, Tsong Fang RH, Chapon C, van der Werf S, Zinn E, Ryan A, Kobayashi DT, Chauhan R, McGlynn M, Ryan ET, Schmidt AG, Price B, Honko A, Griffiths A, Yaghmour S, Hodge R, Betts MR, Freeman MW, Wilson JM, Le Grand R, Vandenberghe LH. Cell Host Microbe. 2021 09 08; 29(9):1437-1453.e8. PMID: 34428428.
    37. Correction: Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh.
      Aktar A, Rahman MA, Afrin S, Akter A, Uddin T, Yasmin T, Sami MIN, Dash P, Jahan SR, Chowdhury F, Khan AI, LaRocque RC, Charles RC, Bhuiyan TR, Mandlik A, Kelly M, Kovác P, Xu P, Calderwood SB, Harris JB, Qadri F, Ryan ET. PLoS Negl Trop Dis. 2021 Jul; 15(7):e0009616. PMID: 34280200.
    38. Defining Polysaccharide-Specific Antibody Targets against Vibrio cholerae O139 in Humans following O139 Cholera and following Vaccination with a Commercial Bivalent Oral Cholera Vaccine, and Evaluation of Conjugate Vaccines Targeting O139.
      Kamruzzaman M, Kelly M, Charles RC, Harris JB, Calderwood SB, Akter A, Biswas R, Kaisar MH, Bhuiyan TR, Ivers LC, Ternier R, Jerome JG, Pfister HB, Lu X, Soliman SE, Ruttens B, Saksena R, Mecárová J, Cížová A, Qadri F, Bystrický S, Kovác P, Xu P, Ryan ET. mSphere. 2021 08 25; 6(4):e0011421. PMID: 34232076.
    39. Development of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: a guide and case study in setting up an emergency-use, laboratory-developed molecular microbiological assay.
      Anahtar MN, Shaw BM, Slater D, Byrne EH, Botti-Lodovico Y, Adams G, Schaffner SF, Eversley J, McGrath GEG, Gogakos T, Lennerz J, Marble HD, Ritterhouse LL, Batten JM, Georgantas NZ, Pellerin R, Signorelli S, Thierauf J, Kemball M, Happi C, Grant DS, Ndiaye D, Siddle KJ, Mehta SB, Harris JB, Ryan ET, Pierce VM, LaRocque RC, Lemieux JE, Sabeti PC, Rosenberg ES, Branda JA, Turbett SE. J Clin Pathol. 2021 Aug; 74(8):496-503. PMID: 34049977.
    40. Vibrio cholerae Sialidase-Specific Immune Responses Are Associated with Protection against Cholera.
      Kaisar MH, Bhuiyan MS, Akter A, Saleem D, Iyer AS, Dash P, Hakim A, Chowdhury F, Khan AI, Calderwood SB, Harris JB, Ryan ET, Qadri F, Charles RC, Bhuiyan TR. mSphere. 2021 04 28; 6(2). PMID: 33910997.
    41. An assessment of potential biomarkers of environment enteropathy and its association with age and microbial infections among children in Bangladesh.
      Uddin MI, Hossain M, Islam S, Akter A, Nishat NS, Nila TA, Rafique TA, Leung DT, Calderwood SB, Ryan ET, Harris JB, LaRocque RC, Bhuiyan TR, Qadri F. PLoS One. 2021; 16(4):e0250446. PMID: 33886672.
    42. Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of Vibrio cholerae O-Specific Polysaccharide-Specific Monoclonal Antibodies.
      Kauffman RC, Adekunle O, Yu H, Cho A, Nyhoff LE, Kelly M, Harris JB, Bhuiyan TR, Qadri F, Calderwood SB, Charles RC, Ryan ET, Kong J, Wrammert J. mBio. 2021 04 20; 12(2). PMID: 33879588.
    43. Parenteral Vaccination with a Cholera Conjugate Vaccine Boosts Vibriocidal and Anti-OSP Responses in Mice Previously Immunized with an Oral Cholera Vaccine.
      Akter A, Kelly M, Charles RC, Harris JB, Calderwood SB, Bhuiyan TR, Biswas R, Xu P, Kovác P, Qadri F, Ryan ET. Am J Trop Med Hyg. 2021 04 19; 104(6):2024-2030. PMID: 33872211.
    44. Humoral signatures of protective and pathological SARS-CoV-2 infection in children.
      Bartsch YC, Wang C, Zohar T, Fischinger S, Atyeo C, Burke JS, Kang J, Edlow AG, Fasano A, Baden LR, Nilles EJ, Woolley AE, Karlson EW, Hopke AR, Irimia D, Fischer ES, Ryan ET, Charles RC, Julg BD, Lauffenburger DA, Yonker LM, Alter G. Nat Med. 2021 03; 27(3):454-462. PMID: 33589825.
    45. Predicting Vibrio cholerae Infection and Disease Severity Using Metagenomics in a Prospective Cohort Study.
      Levade I, Saber MM, Midani FS, Chowdhury F, Khan AI, Begum YA, Ryan ET, David LA, Calderwood SB, Harris JB, LaRocque RC, Qadri F, Shapiro BJ, Weil AA. J Infect Dis. 2021 02 03; 223(2):342-351. PMID: 32610345.
    46. Immunogenicity of an AAV-based, room-temperature stable, single dose COVID-19 vaccine in mice and non-human primates.
      Zabaleta N, Dai W, Bhatt U, Chichester JA, Sanmiguel J, Estelien R, Michalson KT, Diop C, Maciorowski D, Qi W, Hudspeth E, Cucalon A, Dyer CD, Pampena MB, Knox JJ, LaRocque RC, Charles RC, Li D, Kim M, Sheridan A, Storm N, Johnson RI, Feldman J, Hauser BM, Zinn E, Ryan A, Kobayashi DT, Chauhan R, McGlynn M, Ryan ET, Schmidt AG, Price B, Honko A, Griffiths A, Yaghmour S, Hodge R, Betts MR, Freeman MW, Wilson JM, Vandenberghe LH. bioRxiv. 2021 Jan 19. PMID: 33442684.
    47. Yellow Fever Vaccine Administration at Global TravEpiNet (GTEN) Clinics during a Period of Limited Vaccine Availability in the United States, 2017-2018.
      Walker AT, Gershman MD, Rao SR, LaRocque RC, Ryan ET. Am J Trop Med Hyg. 2021 01 18; 104(3):1079-1084. PMID: 33534766.
    48. Acquisition and Long-term Carriage of Multidrug-Resistant Organisms in US International Travelers.
      Worby CJ, Earl AM, Turbett SE, Becker M, Rao SR, Oliver E, Taylor Walker A, Walters M, Kelly P, Leung DT, Knouse M, Hagmann SHF, Ryan ET, LaRocque RC. Open Forum Infect Dis. 2020 Dec; 7(12):ofaa543. PMID: 33409326.
    49. Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events.
      Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, DeRuff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda JA, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, MacInnis BL. Science. 2021 02 05; 371(6529). PMID: 33303686.
    50. Ultra-Sensitive Serial Profiling of SARS-CoV-2 Antigens and Antibodies in Plasma to Understand Disease Progression in COVID-19 Patients with Severe Disease.
      Ogata AF, Maley AM, Wu C, Gilboa T, Norman M, Lazarovits R, Mao CP, Newton G, Chang M, Nguyen K, Kamkaew M, Zhu Q, Gibson TE, Ryan ET, Charles RC, Marasco WA, Walt DR. Clin Chem. 2020 12 01; 66(12):1562-1572. PMID: 32897389.
    51. Humans Surviving Cholera Develop Antibodies against Vibrio cholerae O-Specific Polysaccharide That Inhibit Pathogen Motility.
      Charles RC, Kelly M, Tam JM, Akter A, Hossain M, Islam K, Biswas R, Kamruzzaman M, Chowdhury F, Khan AI, Leung DT, Weil A, LaRocque RC, Bhuiyan TR, Rahman A, Mayo-Smith LM, Becker RL, Vyas JM, Faherty CS, Nickerson KP, Giffen S, Ritter AS, Waldor MK, Xu P, Kovác P, Calderwood SB, Kauffman RC, Wrammert J, Qadri F, Harris JB, Ryan ET. mBio. 2020 11 17; 11(6). PMID: 33203761.
    52. Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality.
      Zohar T, Loos C, Fischinger S, Atyeo C, Wang C, Slein MD, Burke J, Yu J, Feldman J, Hauser BM, Caradonna T, Schmidt AG, Cai Y, Streeck H, Ryan ET, Barouch DH, Charles RC, Lauffenburger DA, Alter G. Cell. 2020 12 10; 183(6):1508-1519.e12. PMID: 33207184.
    53. SARS-CoV-2 viral load is associated with increased disease severity and mortality.
      Fajnzylber J, Regan J, Coxen K, Corry H, Wong C, Rosenthal A, Worrall D, Giguel F, Piechocka-Trocha A, Atyeo C, Fischinger S, Chan A, Flaherty KT, Hall K, Dougan M, Ryan ET, Gillespie E, Chishti R, Li Y, Jilg N, Hanidziar D, Baron RM, Baden L, Tsibris AM, Armstrong KA, Kuritzkes DR, Alter G, Walker BD, Yu X, Li JZ. Nat Commun. 2020 10 30; 11(1):5493. PMID: 33127906.
    54. Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients.
      Iyer AS, Jones FK, Nodoushani A, Kelly M, Becker M, Slater D, Mills R, Teng E, Kamruzzaman M, Garcia-Beltran WF, Astudillo M, Yang D, Miller TE, Oliver E, Fischinger S, Atyeo C, Iafrate AJ, Calderwood SB, Lauer SA, Yu J, Li Z, Feldman J, Hauser BM, Caradonna TM, Branda JA, Turbett SE, LaRocque RC, Mellon G, Barouch DH, Schmidt AG, Azman AS, Alter G, Ryan ET, Harris JB, Charles RC. Sci Immunol. 2020 10 08; 5(52). PMID: 33033172.
    55. Antibody responses after COVID-19 infection in patients who are mildly symptomatic or asymptomatic in Bangladesh.
      Shirin T, Bhuiyan TR, Charles RC, Amin S, Bhuiyan I, Kawser Z, Rahat A, Alam AN, Sultana S, Aleem MA, Khan MH, Khan SR, LaRocque RC, Calderwood SB, Ryan ET, Slater DM, Banu S, Clemens J, Harris JB, Flora MS, Qadri F. Int J Infect Dis. 2020 Dec; 101:220-225. PMID: 33031941.
    56. Reply.
      Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De La Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. J Pediatr. 2021 01; 228:317-319. PMID: 32971143
    57. The effect of transport temperature and time on the recovery of antimicrobial-resistant Enterobacterales in stool.
      Turbett SE, Becker M, Desrosiers L, Oliver E, Rao SR, Walker AT, Walters M, Ryan ET, LaRocque RC. Diagn Microbiol Infect Dis. 2021 Feb; 99(2):115210. PMID: 33242837.
    58. Ultrasensitive high-resolution profiling of early seroconversion in patients with COVID-19.
      Norman M, Gilboa T, Ogata AF, Maley AM, Cohen L, Busch EL, Lazarovits R, Mao CP, Cai Y, Zhang J, Feldman JE, Hauser BM, Caradonna TM, Chen B, Schmidt AG, Alter G, Charles RC, Ryan ET, Walt DR. Nat Biomed Eng. 2020 Sep 18. PMID: 32948854.
    59. Ultra-sensitive Serial Profiling of SARS-CoV-2 Antigens and Antibodies in Plasma to Understand Disease Progression in COVID-19 Patients with Severe Disease.
      Ogata AF, Maley AM, Wu C, Gilboa T, Norman M, Lazarovits R, Mao CP, Newton G, Chang M, Nguyen K, Kamkaew M, Zhu Q, Gibson TE, Ryan ET, Charles RC, Marasco WA, Walt DR. Clin Chem. 2020 Sep 08. PMID: 32897389.
    60. Evolution of Early SARS-CoV-2 and Cross-Coronavirus Immunity.
      Loos C, Atyeo C, Fischinger S, Burke J, Slein MD, Streeck H, Lauffenburger D, Ryan ET, Charles RC, Alter G. mSphere. 2020 09 02; 5(5). PMID: 32878931.
    61. Development of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: A guide and case study in setting up an emergency-use, laboratory-developed molecular assay.
      Anahtar MN, Shaw B, Slater D, Byrne EH, Botti-Lodovico Y, Adams G, Schaffner SF, Eversley JS, McGrath G, Gogakos T, Lennerz J, Marble HD, Ritterhouse LL, Batten J, Georgantas NZ, Pellerin R, Signorelli S, Thierauf J, Kemball M, Happi C, Grant DS, Ndiaye D, Siddle KJ, Mehta SB, Harris JB, Ryan ET, Pierce VM, LaRocque RC, Lemieux J, Sabeti P, Rosenberg E, Branda J, Turbett SE. medRxiv. 2020 Sep 01. PMID: 32909014.
    62. Transcutaneous Vaccination with Conjugate Typhoid Vaccine Vi-DT Induces Systemic, Mucosal, and Memory Anti-Polysaccharide Responses.
      Bhuiyan MS, Kalsy A, Arifuzzaman M, Charles RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. Am J Trop Med Hyg. 2020 Sep; 103(3):1032-1038. PMID: 32720632.
    63. Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital.
      Miller TE, Garcia Beltran WF, Bard AZ, Gogakos T, Anahtar MN, Astudillo MG, Yang D, Thierauf J, Fisch AS, Mahowald GK, Fitzpatrick MJ, Nardi V, Feldman J, Hauser BM, Caradonna TM, Marble HD, Ritterhouse LL, Turbett SE, Batten J, Georgantas NZ, Alter G, Schmidt AG, Harris JB, Gelfand JA, Poznansky MC, Bernstein BE, Louis DN, Dighe A, Charles RC, Ryan ET, Branda JA, Pierce VM, Murali MR, Iafrate AJ, Rosenberg ES, Lennerz JK. FASEB J. 2020 Aug 28. PMID: 32856766.
    64. Evaluation of SARS-CoV-2 serology assays reveals a range of test performance.
      Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk RP, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. Nat Biotechnol. 2020 Aug 27. PMID: 32855547.
    65. Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.
      Lemieux J, Siddle KJ, Shaw BM, Loreth C, Schaffner S, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, Deruff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball M, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda J, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown C, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher G, Madoff LC, Smole S, Pierce VM, Rosenberg ES, Sabeti P, Park DJ, MacInnis BL. medRxiv. 2020 Aug 25. PMID: 32869040.
    66. Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses.
      Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A. J Pediatr. 2020 Aug 18. PMID: 32827525.
    67. Distinct Early Serological Signatures Track with SARS-CoV-2 Survival.
      Atyeo C, Fischinger S, Zohar T, Slein MD, Burke J, Loos C, McCulloch DJ, Newman KL, Wolf C, Yu J, Shuey K, Feldman J, Hauser BM, Caradonna T, Schmidt AG, Suscovich TJ, Linde C, Cai Y, Barouch D, Ryan ET, Charles RC, Lauffenburger D, Chu H, Alter G. Immunity. 2020 09 15; 53(3):524-532.e4. PMID: 32783920.
    68. Dynamics and significance of the antibody response to SARS-CoV-2 infection.
      Iyer AS, Jones FK, Nodoushani A, Kelly M, Becker M, Slater D, Mills R, Teng E, Kamruzzaman M, Garcia-Beltran WF, Astudillo M, Yang D, Miller TE, Oliver E, Fischinger S, Atyeo C, Iafrate AJ, Calderwood SB, Lauer SA, Yu J, Li Z, Feldman J, Hauser BM, Caradonna TM, Branda JA, Turbett SE, LaRocque RC, Mellon G, Barouch DH, Schmidt AG, Azman AS, Alter G, Ryan ET, Harris JB, Charles RC. medRxiv. 2020 Jul 20. PMID: 32743600.
    69. Predicting Vibrio cholerae infection and disease severity using metagenomics in a prospective cohort study.
      Levade I, Saber MM, Midani F, Chowdhury F, Khan AI, Begum YA, Ryan ET, David LA, Calderwood SB, Harris JB, LaRocque RC, Qadri F, Shapiro BJ, Weil AA. J Infect Dis. 2020 Jul 01. PMID: 32610345.
    70. Corrigendum: Isolation, Purification, Characterization and Direct Conjugation of the Lipid A-Free Lipopolysaccharide of Vibrio cholerae O139.
      Xu P, Korcová J, Baráth P, Cížová A, Valáriková J, Qadri F, Kelly M, O'Connor RD, Ryan ET, Bystrický S, Kovác P. Chemistry. 2020 07 17; 26(40):8828. PMID: 32691457.
    71. Evaluation of a Rapid Point-of-Care Multiplex Immunochromatographic Assay for the Diagnosis of Enteric Fever.
      Kumar S, Nodoushani A, Khanam F, DeCruz AT, Lambotte P, Scott R, Bogoch II, Vaidya K, Calderwood SB, Bhuiyan TR, Esfandiari J, Ryan ET, Qadri F, Andrews JR, Charles RC. mSphere. 2020 06 10; 5(3). PMID: 32522777.
    72. Impact of DNA Extraction Method on Variation in Human and Built Environment Microbial Community and Functional Profiles Assessed by Shotgun Metagenomics Sequencing.
      Sui HY, Weil AA, Nuwagira E, Qadri F, Ryan ET, Mezzari MP, Phipatanakul W, Lai PS. Front Microbiol. 2020; 11:953. PMID: 32528434.
    73. Test performance evaluation of SARS-CoV-2 serological assays.
      Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk R, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A. medRxiv. 2020 May 17. PMID: 32511497.
    74. Ultra-Sensitive High-Resolution Profiling of Anti-SARS-CoV-2 Antibodies for Detecting Early Seroconversion in COVID-19 Patients.
      Norman M, Gilboa T, Ogata AF, Maley AM, Cohen L, Cai Y, Zhang J, Feldman JE, Hauser BM, Caradonna TM, Chen B, Schmidt AG, Alter G, Charles RC, Ryan ET, Walt DR. medRxiv. 2020 May 02. PMID: 32511657.
    75. Acquisition of Antibiotic-Resistant Bacteria by U.S. International Travelers.
      Mellon G, Turbett SE, Worby C, Oliver E, Walker AT, Walters M, Kelly P, Leung DT, Knouse M, Hagmann S, Earl A, Ryan ET, LaRocque RC. N Engl J Med. 2020 04 02; 382(14):1372-1374. PMID: 32242366.
    76. Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen.
      Ou L, Kong WP, Chuang GY, Ghosh M, Gulla K, O'Dell S, Varriale J, Barefoot N, Changela A, Chao CW, Cheng C, Druz A, Kong R, McKee K, Rawi R, Sarfo EK, Schön A, Shaddeau A, Tsybovsky Y, Verardi R, Wang S, Wanninger TG, Xu K, Yang GJ, Zhang B, Zhang Y, Zhou T, Arnold FJ, Doria-Rose NA, Lei QP, Ryan ET, Vann WF, Mascola JR, Kwong PD. Sci Rep. 2020 02 20; 10(1):3032. PMID: 32080235.
    77. Clinical Practices for Measles-Mumps-Rubella Vaccination Among US Pediatric International Travelers.
      Hyle EP, Rao SR, Bangs AC, Gastañaduy P, Fiebelkorn AP, Hagmann SHF, Walker AT, Walensky RP, Ryan ET, LaRocque RC. JAMA Pediatr. 2020 Feb 01; 174(2):e194515. PMID: 31816033.
    78. Immune responses to O-specific polysaccharide (OSP) in North American adults infected with Vibrio cholerae O1 Inaba.
      Hossain M, Islam K, Kelly M, Mayo Smith LM, Charles RC, Weil AA, Bhuiyan TR, Kovác P, Xu P, Calderwood SB, Simon JK, Chen WH, Lock M, Lyon CE, Kirkpatrick BD, Cohen M, Levine MM, Gurwith M, Leung DT, Azman AS, Harris JB, Qadri F, Ryan ET. PLoS Negl Trop Dis. 2019 11; 13(11):e0007874. PMID: 31743334.
    79. Characteristics and preparation of the last-minute traveler: analysis of vaccine usage in the Global TravEpiNet Consortium.
      Yates JA, Rao SR, Walker AT, Esposito DH, Sotir M, LaRocque RC, Ryan ET. J Travel Med. 2019 09 02; 26(6). PMID: 31044254.
    80. Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Responses to Live Toxigenic versus Heat-Inactivated Vibrio cholerae.
      Weil AA, Ellis CN, Debela MD, Bhuiyan TR, Rashu R, Bourque DL, Khan AI, Chowdhury F, LaRocque RC, Charles RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. mSphere. 2019 08 21; 4(4). PMID: 31434744.
    81. Posttranslational regulation of IL-23 production distinguishes the innate immune responses to live toxigenic versus heat-inactivated Vibrio cholerae.
      Weil AA, Ellis CN, Debela MD, Bhuiyan TR, Rashu R, Bourque DL, Khan AI, Chowdhury F, LaRocque RC, Charles RC, Ryan ET, Calderwood SB, Qadri F, Harris JB.  mSphere. 2019 Aug 21;4(4). pii: e00206-19. PMC6706466
    82. Induction of systemic, mucosal and memory antibody responses targeting Vibrio cholerae O1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh.
      Akter A, Dash P, Aktar A, Jahan SR, Afrin S, Basher SR, Hakim A, Lisa AK, Chowdhury F, Khan AI, Xu P, Charles RC, Kelly M, Kováč P, Harris JB, Bhuiyan TR, Calderwood SB, Ryan ET*, Qadri F* (co-senior).   PLoS Negl Trop Dis. 2019 Aug 1;13(8):e0007634. PMC6692040.
    83. Isolation, purification, characterization and direct conjugation of the lipid A-free lipopolysaccharide of Vibrio cholerae
      Xu P, Korcová J, Baráth P, Čížová A, Valáriková J, Qadri F, Kelly M, O'Connor RD, Ryan ET, Bystrický S, Kovac P.  Chemistry. 2019 Jul 15. doi: 10.1002/chem.201902263. (in press) PMID: 32691457
    84. Evaluation of a screening method for the detection of colistin-resistant Enterobacteriaceae in stool.
      Turbett SE, Desrosiers L, Andrews-Dunleavey C, Becker M, Walker AT, Esposito D, Woodworth KR, Branda JA, Rosenberg E, Ryan ET, LaRocque R.  Open Forum Infect Dis. 2019 May 6;6(6):ofz211. PMC6559274
    85. Oral immunization with a probiotic cholera vaccine induces broad protective immunity against Vibrio cholerae colonization and disease in mice.
      Sit B, Zhang T, Fakoya B, Akter A, Biswas R, Ryan ET, Waldor MK. PLoS Negl Trop Dis. 2019 May 31;13(5):e0007417. PMC6561597
    86. Characteristics and preparation of the last-minute traveler: analysis of vaccine usage in the Global TravEpiNet Consortium.
      Yates JA, Rao SR, Walker AT, Esposito DH, Sotir M, LaRocque RC, Ryan ET; Global TravEpiNet Consortium.  J Travel Med. 2019 May 1. PMC6736758
    87. Vibriocidal titer and protection from cholera in children.
      Ritter AS, Chowdhury F, Franke MF, Becker RL, Bhuiyan TR, Khan AI, Saha NC, Ryan ET, Calderwood SB, LaRocque RC, Harris JB, Qadri F, Weil AA.  Open Forum Infect Dis. 2019 Feb 11;6(4):ofz057. PMC6457480
    88. Synthesis of glycocluster-containing conjugates for a vaccine against cholera.
      Pfister HB, Kelly M, Qadri F, Ryan ET, Kováč P.  Org Biomol Chem. 2019 Apr 17;17(16):4049-4060. PMID: 30950473
    89. Estimating cholera incidence with cross-sectional serology.
      Azman AS, Lessler J, Luquero FJ, Bhuiyan TR, Khan AI, Chowdhury F, Kabir A, Gurwith M, Weil AA, Harris JB, Calderwood SB, Ryan ET, Qadri F, Leung DT. Science Transl Med. 2019 Feb 20;11(480).  PMC6430585
    90. Emergence of Extensively Drug-Resistant Salmonella Typhi Infections Among Travelers to or from Pakistan - United States, 2016-2018.
      Chatham-Stephens K, Medalla F, Hughes M, Appiah GD, Aubert RD, Caidi H, Angelo KM, Walker AT, Hatley N, Masani S, Nash J, Belko J, Ryan ET, Mintz E, Friedman CR.  MMWR Morb Mortal Wkly Rep. 2019 Jan 11;68(1):11-13.  PMC6342547
    91. Bivalent oral cholera vaccination induces a memory B cell response to the cholerae O1-polysaccharide antigen in Haitian adults.
      Falkard B, Charles RC, Matias WR, Mayo-Smith LM, Jerome JG, Offord ES, Xu P, Kováč P, Ryan ET, Qadri F, Franke MF, Ivers LC, Harris JB. PLoS Negl Trop Dis. 2019 Jan 31;13(1):e0007057. PMC6372202
    92. The Clinical Impact and Cost-effectiveness of Measles-Mumps-Rubella Vaccination to Prevent Measles Importations Among International Travelers From the United States
      Hyle EP, Fields NF, Fiebelkorn AP, Walker AT, Gastañaduy P, Rao SR, Ryan ET, LaRocque RC, Walensky RP.  Clin Infect Dis. PMC6603268
    93. Cognate T and B cell interaction and association of follicular helper T cells with B cell responses in Vibrio cholerae O1 infected Bangladeshi adults.
      Rashu R, Bhuiyan TR, Hoq MR, Hossain L, Paul A, Khan AI, Chowdhury F, Harris JB, Ryan ET, Calderwood SB, Weil AA, Qadri F.  Microbes Infect. 2018 Dec 20. pii: S1286-4579(18)30194-1. PMC6588510
    94. Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016.
      Khalil IA, Troeger C, Blacker BF, Rao PC, Brown A, Atherly DE, Brewer TG, Engmann CM, Houpt ER, Kang G, Kotloff KL, Levine MM, Luby SP, MacLennan CA, Pan WK, Pavlinac PB, Platts-Mills JA, Qadri F, Riddle MS, Ryan ET, Shoultz DA, Steele AD, Walson JL, Sanders JW, Mokdad AH, Murray CJL, Hay SI, Reiner RC Jr. Lancet Infect Dis. 2018 Sep 25. S1473-3099(18)30475-4.  PMC6202441
    95. Potentially serious drug interactions resulting from the pre-travel health encounter.
      Sbaih N, Buss, B, Goyal D, Rao SR, Benefield R, Walker AT, DH, Ryan ET, LaRocque RC, Leung DT, and the Global TravEpiNet Consortium.  Open Forum Infect Dis. 2018 Oct 22;5(11):ofy266. PMC6239081
    96. Defining endemic cholera at three levels of spatiotemporal resolution within Bangladesh.
      Domman D, Chowdhury F, Khan AI, Dorman MJ, Mutreja A, Uddin MI, Paul A, Begum YA, Charles RC, Calderwood SB, Bhuiyan TR, Harris JB, LaRocque RC, Ryan ET*, Qadri F*, Thomson NR* (co-senior).   Nat Genet. 2018 Jul;50(7):951-955. PMC6283067
    97. Plasma IgA responses against two Salmonella Typhi antigens identify patients with typhoid fever.
      Andrews JR, Khanam F, Rahman N, Hossain M, Bogoch II, Vaidya K, Kelly M, Calderwood SB, Bhuiyan TR, Ryan ET, Qadri F, Charles,  Clin Infect Dis. 2019 Mar 5;68(6):949-955. PMC6399438
    98. Human Gut Microbiota Predicts Susceptibility to Vibrio cholerae
      Midani FS, Weil AA, Chowdhury F, Begum YA, Khan AI, Debela MD, Durand HK, Reese AT, Nimmagadda SN, Silverman JD, Ellis CN, Ryan ET, Calderwood SB, Harris JB, Qadri F, David LA, LaRocque RC.  J Infect Dis. 2018 Jul 13;218(4):645-653. PMC6047457.
    99. Plasma and memory B cell responses targeting O-specific polysaccharide (OSP) are associated with protection against Vibrio cholerae O1 infection among household contacts of cholera patients in Bangladesh.
      Aktar A, Rahman MA, Afrin S, Akter A, Uddin T, Yasmin T, Nur Sami MI, Dash P, Jahan SR, Chowdhury F, Khan AI, LaRocque RC, Charles RC, Bhuiyan TR, Mandlik A, Kelly M, Kováč P, Xu P, Calderwood SB, Harris JB, Qadri F*, Ryan ET* (co-senior).  PLoS Negl Trop Dis. 2018 Apr 23;12(4):e0006399. PMC5912711
    100. Anti-O-specific polysaccharide (OSP) immune responses following vaccination with oral cholera vaccine CVD 103-HgR correlate with protection against cholera after infection with wild-type Vibrio cholerae O1 El Tor Inaba in North American volunteers.
      Islam K, Hossain M, Kelly M, Mayo Smith LM, Charles RC, Bhuiyan TR, Kováč P, Xu P, LaRocque RC, Calderwood SB, Simon JK, Chen WH, Haney D, Lock M, Lyon CE, Kirkpatrick BD, Cohen M, Levine MM, Gurwith M, Harris JB, Qadri F*, Ryan ET* (co-senior).   PLoS Negl Trop Dis. 2018 Apr 6;12(4):e0006376.  PMC5906022
    101. Development of a new dipstick (Cholkit) for rapid detection of Vibrio cholerae O1 in acute watery diarrheal stools.
      Sayeed MA, Islam K, Hossain M, Akter NJ, Alam MN, Sultana N, Khanam F, Kelly M, Charles RC, Kováč P, Xu P, Andrews JR, Calderwood SB, Amin JA, Ryan ET*, Qadri F* (co-senior).  PLoS Negl Trop Dis. 2018 Mar 14;12(3):e0006286.  PMC5862499
    102. Dried blood spots for measuring Vibrio cholerae-specific immune responses.
      Iyer AS, Azman AS, Bouhenia M, Deng LO, Graves M, Anderson CP, Kováč P, Xu P, Ryan ET, Harris JB, Sack DA, Luquero FJ, Leung  PLoS Negl Trop Dis. 2018 Jan 29;12(1):e0006196.  PMC5805362
    103. Vibrio cholerae genomic diversity within and between patients.
      Levade I, Terrat Y, Leducq JB, Weil AA, Mayo-Smith LM, Chowdhury F, Khan AI, Boncy J, Buteau J, Ivers LC, Ryan ET, Charles RC, Calderwood SB, Qadri F, Harris JB, LaRocque RC, Shapiro BJ. Microb Genom. 2017 Dec; 3(12): e000142.
    104. Enabling clinicians to easily find location-based travel health recommendations-is innovation needed?
      Lash RR, Walker AT, Lee CV, LaRocque R, Rao SR, Ryan ET, Brunette G, Holton K, Sotir MJ.  J Travel Med. 2018 Jan 1;25(1). PMID: 29788401.
    105. HIV infection, pulmonary tuberculosis, and COPD in rural Uganda: a cross-sectional study.
      North CM, Allen JG, Okello S, Sentongo R, Kakuhikire B, Ryan ET, Tsai AC, Christiani DC, Siedner MJ.  Lung. 2018 Feb;196(1):49-57. PMID: 29260309.
    106. Nanomagnetic System for Rapid Diagnosis of Acute Infection
      Park K, Kim H, Kim S, Lee K, Park S, Song J, Min C, Khanam F, Rashu R, Bhuiyan TR, Ryan ET, Qadri F, Weissleder R, Cheon J, Charles RC, Lee H.  ACS Nano 2017;11(11):11425-11432. PMID: 29121461.
    107. Analysis of the human mucosal response to cholera reveals sustained activation of innate immune signaling pathways.
      Bourque D, Bhuiyan T, Genereux D, Rashu R, Ellis C, Chowdhury F, Khan A, Alam NH, Hossain AL, Mayo-Smith L, Charles RC, Weil A, LaRocque RC, Calderwood SB, Ryan ET, Karlsson E, Qadri F, Jason B. Harris JB.  Infect Immun. 2018 Jan 22;86(2). PMC5778365.
    108. Assessing antigen specific HLA-DR+ antibody secreting cell (DR+ASC) responses in whole blood in enteric infections using an ELISPOT technique.
      Bhuiyan TR, Hoq MR, Nishat NS, Mahbuba DA, Rashu R, Islam K, Hossain L, Harris JB, Ryan ET, Calderwood SB, Svennerholm AN, Qadri  Microbes Infect. 2018 Feb;20(2):122-129. PMID: 29104143.
    109. Travel Characteristics and Pretravel Health Care Among Pregnant or Breastfeeding U.S. Women Preparing for International Travel.
      Hagmann SHF, Rao SR, LaRocque RC, Erskine S, Jentes ES, Walker AT, Barnett ED, Chen LH, Hamer DH, Ryan ET, for the Global TravEpiNet Consortium and the Boston Area Travel Medicine Network.   Obstetrics & Gynecology. 2017;130(6):1357-1365.
    110. Plasma and Mucosal Immunoglobulin M, Immunoglobulin A, and Immunoglobulin G Responses to the Vibrio cholerae O1 Protein Immunome in Adults With Cholera in Bangladesh
      Charles RC, Nakajima R, Liang L, Jasinskas A, Berger A, Leung DT, Kelly M, Xu P, Kováč P, Giffen SG, Harbison JD, Chowdhury F, Khan AI, Calderwood SB, Bhuiyan TR, Harris JB, Felgner PL, Qadri F, Ryan ET.   J Infect Dis. 2017 Jul 1;216(1):125-134.
    111. High rates of enteric fever diagnosis and lower burden of culture-confirmed disease in peri-urban and rural Nepal.
      Andrews JR, Vaidya K, Bern C, Tamrakar D, Wen S, Madhup S, Shrestha R, Karmacharya B, Amatya B, Koju R, Adhikari SR, Hohmann E, Ryan ET, Bogoch  J Infect Dis. 2018 11 10; 218(suppl_4):S214-S221. PMID: 28961918.
    112. What proportion of international travellers acquire a travel-related illness? A review of the literature.
      Angelo KM, Kozarsky PE, Ryan ET, Chen LH, Sotir MJ.  J Travel Med. 2017 Sep 1;24(5). PMC5825178
    113. The plasma and mucosal IgM, IgA, and IgG responses to the Vibrio cholerae O1 protein immunome in adults with cholera in Bangladesh.
      Charles RC, Nakajima R, Liang L, Jasinskas A, Berger A, Leung DT, Kelly M, Xu P, Kovác P, Giffen SR, Harbison JD, Chowdhury F, Khan AI, Calderwood SB, Bhuiyan TR, Harris JB, Felgner PL, Qadri F, Ryan ET. J Infect Dis. 2017 May 23. PMID: 28535267
    114. Missed Opportunities for Measles, Mumps, Rubella Vaccination Among Departing U.S. Adult Travelers Receiving Pretravel Health Consultations.
      Hyle EP, Rao SR, Jentes ES, Fiebelkorn AP, Hagmann SHF, Walker AT, Walensky RP, Ryan ET, LaRocque RC. Ann Intern Med. 2017 May 16. doi: 10.7326/M16-2249. PMID: 28505632
    115. Recommendations of the Advisory Committee on Immunization Practices for Use of Cholera Vaccine.
      Wong KK, Burdette E, Mahon BE, Mintz ED, Ryan ET, Reingold AL. MMWR Morb Mortal Wkly Rep. 2017 May 12;66(18):482-485. doi: 10.15585/mmwr.mm6618a6. PMID: 28493859
    116. Conjugate Vaccines from Bacterial Antigens by Squaric Acid Chemistry: A Closer Look.
      Xu P, Kelly M, Vann WF, Qadri F, Ryan ET, Ková? P. Chembiochem. 2017 Apr 18;18(8):799-815. doi: 10.1002/cbic.201600699. Epub 2017 Mar 23. PMID: 28182850
    117. Preparing Pediatric International Travelers for Travelers' Diarrhea: Insights From the Global TravEpiNet.
      Hagmann SH, LaRocque RC, Ryan ET. Pediatr Infect Dis J. 2017 Feb;36(2):242-243. doi: 10.1097/INF.0000000000001402. PMID: 28079839
    118. Single-Cell Analysis of the Plasmablast Response to Vibrio cholerae Demonstrates Expansion of Cross-Reactive Memory B Cells.
      Kauffman RC, Bhuiyan TR, Nakajima R, Mayo-Smith LM, Rashu R, Hoq MR, Chowdhury F, Khan AI, Rahman A, Bhaumik SK, Harris L, O'Neal JT, Trost JF, Alam NH, Jasinskas A, Dotsey E, Kelly M, Charles RC, Xu P, Ková? P, Calderwood SB, Ryan ET, Felgner PL, Qadri F, Wrammert J, Harris JB. MBio. 2016 Dec 20;7(6). pii: e02021-16. doi: 10.1128/mBio.02021-16. PMID: 27999163
    119. Characteristics of US Travelers to Zika Virus-Affected Countries in the Americas, March 2015-October 2016.
      Lammert S, Walker AT, Erskine S, Rao SR, Esposito DH, Ryan ET, Robbins GK, LaRocque RC. Emerg Infect Dis. 2017 Feb;23(2):324-327. doi: 10.3201/eid2302.161292. PMID: 27926355
    120. Biomarkers of Environmental Enteropathy are Positively Associated with Immune Responses to an Oral Cholera Vaccine in Bangladeshi Children.
      Uddin MI, Islam S, Nishat NS, Hossain M, Rafique TA, Rashu R, Hoq MR, Zhang Y, Saha A, Harris JB, Calderwood SB, Bhuiyan TR, Ryan ET, Leung DT, Qadri F. PLoS Negl Trop Dis. 2016 Nov 8;10(11):e0005039. doi: 10.1371/journal.pntd.0005039. PMID: 27824883
    121. Refusal of recommended travel-related vaccines among U.S. international travellers in Global TravEpiNet.
      Lammert SM, Rao SR, Jentes ES, Fairley JK, Erskine S, Walker AT, Hagmann SH, Sotir MJ, Ryan ET, LaRocque RC. J Travel Med. 2016 Oct 30;24(1). pii: taw075. PMID: 27799502
    122. Immune Responses to an Oral Cholera Vaccine in Internally Displaced Persons in South Sudan.
      Iyer AS, Bouhenia M, Rumunu J, Abubakar A, Gruninger RJ, Pita J, Lino RL, Deng LL, Wamala JF, Ryan ET, Martin S, Legros D, Lessler J, Sack DA, Luquero FJ, Leung DT, Azman AS. Sci Rep. 2016 Oct 24;6:35742. doi: 10.1038/srep35742. PMID: 27775046
    123. Personal Actions to Minimize Mosquito-Borne Illnesses, Including Zika Virus.
      LaRocque RL, Ryan ET. Ann Intern Med. 2016 Oct 18;165(8):589-590. doi: 10.7326/M16-1397. PMID: 27399646
    124. Medical Considerations before International Travel.
      LaRocque RC, Ryan ET. N Engl J Med. 2016 Oct 13;375(15):e32. PMID: 27732815
    125. A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever.
      Park KS, Chung HJ, Khanam F, Lee H, Rashu R, Bhuiyan MT, Berger A, Harris JB, Calderwood SB, Ryan ET, Qadri F, Weissleder R, Charles RC. Sci Rep. 2016 Sep 8;6:32878. doi: 10.1038/srep32878. PMID: 27605393
    126. Antibody Secreting Cell Responses following Vaccination with Bivalent Oral Cholera Vaccine among Haitian Adults.
      Matias WR, Falkard B, Charles RC, Mayo-Smith LM, Teng JE, Xu P, Ková? P, Ryan ET, Qadri F, Franke MF, Ivers LC, Harris JB. PLoS Negl Trop Dis. 2016 Jun 16;10(6):e0004753. doi: 10.1371/journal.pntd.0004753. PMID: 27308825
    127. Erratum: Chemoproteomic profiling of host and pathogen enzymes active in cholera.
      Hatzios SK, Abel S, Martell J, Hubbard T, Sasabe J, Munera D, Clark L, Bachovchin DA, Qadri F, Ryan ET, Davis BM, Weerapana E, Waldor MK. Nat Chem Biol. 2016 May 18;12(6):466. doi: 10.1038/nchembio0616-466. PMID: 27191648
    128. Comparison of the Performance of the TPTest, Tubex, Typhidot and Widal Immunodiagnostic Assays and Blood Cultures in Detecting Patients with Typhoid Fever in Bangladesh, Including Using a Bayesian Latent Class Modeling Approach.
      Islam K, Sayeed MA, Hossen E, Khanam F, Charles RC, Andrews J, Ryan ET, Qadri F. PLoS Negl Trop Dis. 2016 Apr 8;10(4):e0004558. doi: 10.1371/journal.pntd.0004558. PMID: 27058877
    129. O-specific polysaccharide (OSP)-specific memory B cell responses in young children, older children and adults infected with Vibrio cholerae O1 Ogawa in Bangladesh. Aktar A, Rahman MA, Afrin S, Faruk MO, Uddin T, Akter A, Sami MI, Yasmin T, Chowdhury F, Khan AI, Leung DT, LaRocque RC, Charles RC, Bhuiyan TR, Mandlik A, Bufano MK, Ková? P, Xu P, Calderwood SB, Harris JB, Qadri F, Ryan ET. O-specific polysaccharide (OSP)-specific memory B cell responses in young children, older children and adults infected with Vibrio cholerae O1 Ogawa in Bangladesh. Clin Vaccine Immunol (in press). PMC in process.
    130. Comparison of the Performance of the TPTest, Tubex, Typhidot and Widal Immunodiagnostic Assays and Blood Cultures in Detecting Patients with Typhoid Fever in Bangladesh, Including Using a Bayesian Latent Class Modeling Approach. Islam K, Sayeed MA, Hossen E, Khanam F, Charles RC, Andrews J, Ryan ET, Qadri F. Comparison of the performance of the TPTest, Tubex, Typhidot and Widal immunodiagnostic assays and blood cultures in detecting patients with typhoid fever in Bangladesh, including using a Bayesian latent class modeling approach. PLoS Negl Trop Dis. 2016 Apr 8;10(4):e0004558. PMC4825986
    131. Development of a simple, peripheral blood-based lateral-flow dipstick assay for accurate detection of patients with enteric fever. Khan IH, Sayeed MA, Sultana N, Islam K, Amin J, Faruk MO, Khan U, Khanam F, Ryan ET, Qadri F. Development of a simple, peripheral blood-based lateral-flow dipstick assay for accurate detection of patients with enteric fever. Clin Vaccine Immunol (in press). PMC in process.
    132. Chemoproteomic profiling of host and pathogen enzymes active in cholera Hatzios SK, Abel S, Martell J, Hubbard T, Sasabe J, Munera D, Clark L, Bachovchin DA, Qadri F, Ryan ET, Davis BM, Weerapana E, Waldor MK. Chemoproteomic profiling of host and pathogen enzymes active in cholera. Nature Chemical Biology. 2016 Apr;12(4):268-74. PMC4765928.
    133. Safe and Healthy International Travel. Lammert S, Ryan ET, LaRoque RC. JAMA. 2015 Dec 15;314(23):2580. doi: 10.1001/jama.2015.15012. PMID: 26670985
    134. Vibrio cholerae Serogroup O139: Isolation from Cholera Patients and Asymptomatic Household Family Members in Bangladesh between 2013 and 2014. Chowdhury F, Mather AE, Begum YA, Asaduzzaman M, Baby N, Sharmin S, Biswas R, Ikhtear Uddin M, LaRocque RC, Harris JB, Calderwood SB, Ryan ET, Clemens JD, Thomson NR, Qadri F. PLoS Negl Trop Dis. 2015 Nov 12;9(11):e0004183. doi: 10.1371/journal.pntd.0004183. eCollection 2015 Nov.
      PMID: 26562418 Free PMC Article
    135. Enumeration of gut-homing β7-positive, pathogen-specific antibody secreting cells in whole blood in enterotoxigenic Escherichia coli and Vibrio cholerae-infected patients using an ELISPOT technique.Bhuiyan TR, Hoq MR, Nishat NS, Al Mahbuba D, Rashu R, Islam K, Hossain L, Dey A, Harris JB, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F. Clin Vaccine Immunol. 2015 Oct 28. pii: CVI.00526-15. [Epub ahead of print] PMID: 26512047
    136. Pre-Travel Medical Preparation of Business and Occupational Travelers: An Analysis of the Global TravEpiNet Consortium, 2009 to 2012. Khan NM, Jentes ES, Brown C, Han P, Rao SR, Kozarsky P, Hagmann SH, LaRocque RC, Ryan ET; Global TravEpiNet Consortium (GTEN). J Occup Environ Med. 2015 Oct 15. [Epub ahead of print] PMID: 26479857
    137. Fluorescence Polarization Based Nucleic Acid Testing for Rapid and Cost-Effective Diagnosis of Infectious Disease. Park KS, Charles RC, Ryan ET, Weissleder R, Lee H. Chemistry. 2015 Nov 9;21(46):16359-63. doi: 10.1002/chem.201502934. Epub 2015 Sep 30. PMID: 26420633
    138. The increased severity in patients presenting to hospital with diarrhea in Dhaka, Bangladesh since the emergence of the hybrid strain of Vibrio cholerae O1 is not unique to cholera patients. Chowdhury F, Kuchta A, Khan AI, Faruque AS, Calderwood SB, Ryan ET, Qadri F. Int J Infect Dis. 2015 Nov;40:9-14. doi: 10.1016/j.ijid.2015.09.007. Epub 2015 Sep 25. PMID: 26409202 Free Article
    139. Factors Associated with Non-typhoidal Salmonella Bacteremia versus Typhoidal Salmonella Bacteremia in Patients Presenting for Care in an Urban Diarrheal Disease Hospital in Bangladesh. Shahunja KM, Leung DT, Ahmed T, Bardhan PK, Ahmed D, Qadri F, Ryan ET, Chisti MJ. PLoS Negl Trop Dis. 2015 Sep 11;9(9):e0004066. doi: 10.1371/journal.pntd.0004066. eCollection 2015 Sep.
      PMID: 26361076 Free PMC Article
    140. Immunocompromised Travelers: Demographic Characteristics, Travel Destinations, and Pretravel Health Care from the U.S. Global TravEpiNet Consortium. Schwartz BS, Rosen J, Han PV, Hynes NA, Hagmann SH, Rao SR, Jentes ES, Ryan ET, LaRocque RC; Global TravEpiNet Consortium. Am J Trop Med Hyg. 2015 Nov 4;93(5):1110-6. doi: 10.4269/ajtmh.15-0185. Epub 2015 Aug 24. PMID: 26304922
    141. Cholera in pregnancy: Clinical and immunological aspects. Khan AI, Chowdhury F, Leung DT, Larocque RC, Harris JB, Ryan ET, Calderwood SB, Qadri F.
      Int J Infect Dis. 2015 Oct;39:20-4. doi: 10.1016/j.ijid.2015.08.006. Epub 2015 Aug 14.
    142. A Cholera Conjugate Vaccine Containing O-specific Polysaccharide (OSP) of V. cholerae O1 Inaba and Recombinant Fragment of Tetanus Toxin Heavy Chain (OSP:rTTHc) Induces Serum, Memory and Lamina Proprial Responses against OSP and Is Protective in Mice. Sayeed MA, Bufano MK, Xu P, Eckhoff G, Charles RC, Alam MM, Sultana T, Rashu MR, Berger A, Gonzalez-Escobedo G, Mandlik A, Bhuiyan TR, Leung DT, LaRocque RC, Harris JB, Calderwood SB, Qadri F, Vann WF, Ková? P, Ryan ET. PLoS Negl Trop Dis. 2015 Jul 8;9(7):e0003881. doi: 10.1371/journal.pntd.0003881. eCollection 2015 Jul. PMID: 26154421
    143. Concurrent Pneumonia in Children Under 5 Years of Age Presenting to a Diarrheal Hospital in Dhaka, Bangladesh. Leung DT, Das SK, Malek MA, Qadri F, Faruque AS, Chisti MJ, Ryan ET. Am J Trop Med Hyg. 2015 Jul 6. pii: 15-0074. PMID: 26149863
    144. Plasma Leptin Levels in Children Hospitalized with Cholera in Bangladesh. Falkard B, Uddin T, Arifur Rahman M, Franke MF, Aktar A, Uddin MI, Bhuiyan TR, Leung DT, Charles RC, Larocque RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. Am J Trop Med Hyg. 2015 Jun 8. pii: 15-0172. PMID: 26055740
    145. Gut microbial succession follows acute secretory diarrhea in humans. David LA, Weil A, Ryan ET, Calderwood SB, Harris JB, Chowdhury F, Begum Y, Qadri F, LaRocque RC, Turnbaugh PJ. MBio. 2015 May 19;6(3):e00381-15. doi: 10.1128/mBio.00381-15. PMID: 25991682
    146. Diagnostics for invasive Salmonella infections: Current challenges and future directions. Andrews JR, Ryan ET. Vaccine. 2015 Jun 19;33 Suppl 3:C8-C15. doi: 10.1016/j.vaccine.2015.02.030. Epub 2015 Apr 30. Review. PMID: 25937611
    147. Typhoid fever in young children in Bangladesh: clinical findings, antibiotic susceptibility pattern and immune responses. Khanam F, Sayeed MA, Choudhury FK, Sheikh A, Ahmed D, Goswami D, Hossain ML, Brooks A, Calderwood SB, Charles RC, Cravioto A, Ryan ET, Qadri F. PLoS Negl Trop Dis. 2015 Apr 7;9(4):e0003619. doi: 10.1371/journal.pntd.0003619. eCollection 2015 Apr.
      PMID: 25849611
    148. Immunogenicity of the Bivalent Oral Cholera Vaccine Shanchol in Haitian Adults With HIV Infection.
    149. Ivers LC, Charles RC, Hilaire IJ, Mayo-Smith LM, Teng JE, Jerome JG, Rychert J, LaRocque RC, Xu P, Ková? P, Ryan ET, Qadri F, Almazor CP, Franke MF, Harris JB. J Infect Dis. 2015 Feb 26. pii: jiv108. [Epub ahead of print] PMID: 25722294
    150. Comparative proteomic analysis reveals activation of mucosal innate immune signaling pathways during cholera. Ellis CN, LaRocque RC, Uddin T, Krastins B, Mayo-Smith LM, Sarracino D, Karlsson EK, Rahman A, Shirin T, Bhuiyan TR, Chowdhury F, Khan AI, Ryan ET, Calderwood SB, Qadri F, Harris JB.
      Infect Immun. 2015 Mar;83(3):1089-103. doi: 10.1128/IAI.02765-14. Epub 2015 Jan 5. PMID: 25561705 [PubMed - indexed for MEDLINE]
    151. Household Transmission of Vibrio cholerae in Bangladesh. Sugimoto JD, Koepke AA, Kenah EE, Halloran ME, Chowdhury F, Khan AI, LaRocque RC, Yang Y, Ryan ET, Qadri F, Calderwood SB, Harris JB, Longini IM Jr. PLoS Negl Trop Dis. 2014 Nov 20;8(11):e3314. doi: 10.1371/journal.pntd.0003314. eCollection 2014 Nov. PMID: 25411971 [PubMed - in process]
    152. Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of Vibrio cholerae. Rychert J, Creely D, Mayo-Smith LM, Calderwood SB, Ivers LC, Ryan ET, Boncy J, Qadri F, Ahmed D, Ferraro MJ, Harris JB. J Clin Microbiol. 2015 Jan;53(1):329-31. doi: 10.1128/JCM.02666-14. Epub 2014 Nov 12. PMID: 25392355
    153. Environmental enteric dysfunction: pathogenesis, diagnosis, and clinical consequences. Keusch GT, Denno DM, Black RE, Duggan C, Guerrant RL, Lavery JV, Nataro JP, Rosenberg IH, Ryan ET, Tarr PI, Ward H, Bhutta ZA, Coovadia H, Lima A, Ramakrishna B, Zaidi AK, Hay Burgess DC, Brewer T.
      Clin Infect Dis. 2014 Nov 1;59 Suppl 4:S207-12. doi: 10.1093/cid/ciu485. Review. PMID: 25305288
    154. Hepatic hydatid cyst: a rare cause of recurrent pancreatitis. Kitchens WH, Liu C, Ryan ET, Fernandez-del Castillo C. J Gastrointest Surg. 2014 Nov;18(11):2057-9. doi: 10.1007/s11605-014-2630-1. Epub 2014 Aug 23. PMID: 25149853 [PubMed - indexed for MEDLINE]
    155. Circulating mucosal associated invariant T cells are activated in Vibrio cholerae O1 infection and associated with lipopolysaccharide antibody responses. Leung DT, Bhuiyan TR, Nishat NS, Hoq MR, Aktar A, Rahman MA, Uddin T, Khan AI, Chowdhury F, Charles RC, Harris JB, Calderwood SB, Qadri F, Ryan ET.
      PLoS Negl Trop Dis. 2014 Aug 21;8(8):e3076. doi: 10.1371/journal.pntd.0003076. eCollection 2014 Aug. PMID: 25144724 [PubMed - in process]
    156. Bacterial shedding in household contacts of cholera patients in Dhaka, Bangladesh. Weil AA, Begum Y, Chowdhury F, Khan AI, Leung DT, LaRocque RC, Charles RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Am J Trop Med Hyg. 2014 Oct;91(4):738-42. doi: 10.4269/ajtmh.14-0095. Epub 2014 Aug 11. PMID: 25114012 [PubMed - indexed for MEDLINE]
    157. Use of Japanese encephalitis vaccine in US travel medicine practices in Global TravEpiNet. Deshpande BR, Rao SR, Jentes ES, Hills SL, Fischer M, Gershman MD, Brunette GW, Ryan ET, LaRocque RC; Global TravEpiNet Consortium.
      Am J Trop Med Hyg. 2014 Oct;91(4):694-8. doi: 10.4269/ajtmh.14-0062. Epub 2014 Jul 28. PMID: 25070999 [PubMed - indexed for MEDLINE]
    158. Salmonella chronic carriage: epidemiology, diagnosis, and gallbladder persistence. Gunn JS, Marshall JM, Baker S, Dongol S, Charles RC, Ryan ET.
      Trends Microbiol. 2014 Nov;22(11):648-55. doi: 10.1016/j.tim.2014.06.007. Epub 2014 Jul 22. Review. PMID: 25065707 [PubMed - indexed for MEDLINE]
    159. Immunogenicity of a killed bivalent (O1 and O139) whole cell oral cholera vaccine, Shanchol, in Haiti.Charles RC, Hilaire IJ, Mayo-Smith LM, Teng JE, Jerome JG, Franke MF, Saha A, Yu Y, Ková? P, Calderwood SB, Ryan ET, LaRocque RC, Almazor CP, Qadri F, Ivers LC, Harris JB. PLoS Negl Trop Dis. 2014 May 1;8(5):e2828. doi: 10.1371/journal.pntd.0002828. eCollection 2014 May. PMID: 24786645 [PubMed - indexed for MEDLINE]
    160. Antigen-specific memory B-cell responses to enterotoxigenic Escherichia coli infection in Bangladeshi adults. Alam MM, Aktar A, Afrin S, Rahman MA, Aktar S, Uddin T, Rahman MA, Al Mahbuba D, Chowdhury F, Khan AI, Bhuiyan TR, Begum YA, Ryan ET, Calderwood SB, Svennerholm AM, Qadri F. PLoS Negl Trop Dis. 2014 Apr 24;8(4):e2822. doi: 10.1371/journal.pntd.0002822. eCollection 2014 Apr. PMID: 24762744 [PubMed - indexed for MEDLINE]
    161. Immune responses to O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 Ogawa in adult Bangladeshi recipients of an oral killed cholera vaccine and comparison to responses in patients with cholera. Uddin T, Aktar A, Xu P, Johnson RA, Rahman MA, Leung DT, Afrin S, Akter A, Alam MM, Rahman A, Chowdhury F, Khan AI, Bhuiyan TR, Bufano MK, Rashu R, Yu Y, Wu-Freeman Y, Harris JB, LaRocque RC, Charles RC, Ková? P, Calderwood SB, Ryan ET, Qadri F. Am J Trop Med Hyg. 2014 May;90(5):873-81. doi: 10.4269/ajtmh.13-0498. Epub 2014 Mar 31. PMID: 24686738 [PubMed - indexed for MEDLINE]
    162. Cellular and cytokine responses to Salmonella enterica serotype Typhi proteins in patients with typhoid fever in Bangladesh. Bhuiyan S, Sayeed A, Khanam F, Leung DT, Rahman Bhuiyan T, Sheikh A, Salma U, LaRocque RC, Harris JB, Pacek M, Calderwood SB, LaBaer J, Ryan ET, Qadri F, Charles RC. Am J Trop Med Hyg. 2014 Jun;90(6):1024-30. doi: 10.4269/ajtmh.13-0261. Epub 2014 Mar 10. PMID: 24615129
    163. Evaluation in mice of a conjugate vaccine for cholera made from Vibrio cholerae O1 (Ogawa) O-specific polysaccharide. Alam MM, Bufano MK, Xu P, Kalsy A, Yu Y, Freeman YW, Sultana T, Rashu MR, Desai I, Eckhoff G, Leung DT, Charles RC, LaRocque RC, Harris JB, Clements JD, Calderwood SB, Qadri F, Vann WF, Ková? P, Ryan ET. PLoS Negl Trop Dis. 2014 Feb 6;8(2):e2683. doi: 10.1371/journal.pntd.0002683. eCollection 2014 Feb. PMID: 24516685
    164. Pre-travel preparation of US travelers going abroad to provide humanitarian service, Global TravEpiNet 2009-2011. Stoney RJ, Jentes ES, Sotir MJ, Kozarsky P, Rao SR, Larocque RC, Ryan ET; Global TravEpiNet Consortium. Am J Trop Med Hyg. 2014 Mar;90(3):553-9. doi: 10.4269/ajtmh.13-0479. Epub 2014 Jan 20.
      PMID: 24445203
    165. Impact of Ramadan on Clinical and Microbiologic Parameters of Patients Seen at a Diarrheal Hospital in Urban Dhaka, Bangladesh, 1996-2012. Leung DT, Das SK, Malek MA, Qadri F, Faruque AS, Ryan ET. Am J Trop Med Hyg. 2014 Jan 6. [Epub ahead of print] PMID: 24394479
    166. Immunoproteomic analysis of antibody-in-lymphocyte supernatant (ALS) in patients with typhoid fever in Bangladesh. Charles RC, Liang L, Khanam F, Sayeed MA, Hung C, Leung DT, Baker S, Ludwig A, Harris JB, Larocque RC, Calderwood SB, Qadri F, Felgner PL, Ryan ET. Clin Vaccine Immunol. 2013 Dec 26. [Epub ahead of print] PMID: 24371257
    167. Implications of acquired environmental enteric dysfunction for growth and stunting in infants and children living in low- and middle-income countries. Keusch GT, Rosenberg IH, Denno DM, Duggan C, Guerrant RL, Lavery JV, Tarr PI, Ward HD, Black RE, Nataro JP, Ryan ET, Bhutta ZA, Coovadia H, Lima A, Ramakrishna B, Zaidi AK, Burgess DC, Brewer T. Food Nutr Bull. 2013 Sep;34(3):357-64. Review. PMID: 24167916
    168. Eyes on the prize: lessons from the cholera wars for modern scientists, physicians, and public health officials. Ryan ET. Am J Trop Med Hyg. 2013 Oct;89(4):610-4. doi: 10.4269/ajtmh.13-0173. PMID: 24106185
    169. The intestinal pathobiome: its reality and consequences among infants and young children in resource-limited settings.  Ryan ET. J Infect Dis. 2013 Dec 1;208(11):1732-3. doi: 10.1093/infdis/jit509. Epub 2013 Sep 16. PMID: 24041794
    170. Economics of Malaria Prevention in US Travelers to West Africa.  Adachi K, Coleman MS, Khan N, Jentes ES, Arguin P, Rao SR, Larocque RC, Sotir MJ, Brunette G, Ryan ET, Meltzer MI; Global TravEpiNet Consortium. Clin Infect Dis. 2014 Jan;58(1):11-21. doi: 10.1093/cid/cit570. Epub 2013 Sep 6. PMID: 24014735
    171. Evaluation of a typhoid/paratyphoid diagnostic assay (TPTest) detecting anti-Salmonella IgA in secretions of peripheral blood lymphocytes in patients in Dhaka, Bangladesh. Khanam F, Sheikh A, Sayeed MA, Bhuiyan MS, Choudhury FK, Salma U, Pervin S, Sultana T, Ahmed D, Goswami D, Hossain ML, Mamun KZ, Charles RC, Brooks WA, Calderwood SB, Cravioto A, Ryan ET, Qadri F. PMID: 23951368
    172. Antibody secreting cell responses after Vibrio cholerae O1 infection and oral cholera vaccination in adults in Bangladesh.  Rahman A, Rashu R, Bhuiyan TR, Chowdhury F, Khan AI, Islam K, Larocque RC, Ryan ET, Wrammert J, Calderwood SB, Qadri F, Harris JB. Clin Vaccine Immunol. 2013 Aug 14. [Epub ahead of print] PMID: 23945156
    173. Identification of Immunogenic Salmonella enterica Serotype Typhi Antigens Expressed in Chronic Biliary Carriers of S. Typhi in Kathmandu, Nepal.  Charles RC, Sultana T, Alam MM, Yu Y, Wu-Freeman Y, Bufano MK, Rollins SM, Tsai L, Harris JB, Larocque RC, Leung DT, Brooks WA, Nga TV, Dongol S, Basnyat B, Calderwood SB, Farrar J, Khanam F, Gunn JS, Qadri F, Baker S, Ryan ET. PLoS Negl Trop Dis. 2013 Aug 1;7(8):e2335. doi: 10.1371/journal.pntd.0002335. Print 2013 Aug. PMID: 23936575
    174. Antibody avidity following administration of an oral killed cholera vaccine: comparing humoral immune responses in Bangladeshi children with those in adults. Alam MM, Leung DT, Akhtar M, Nazim M, Akter S, Uddin T, Khanam F, Mahbuba DA, Ahmad SM, Bhuiyan TR, Calderwood SB, Ryan ET, Qadri F. Clin Vaccine Immunol. 2013 Aug 7. [Epub ahead of print] PMID: 23925888
    175. Evaluation of an electricity-free, culture-based approach for detecting typhoidal Salmonella bacteremia during enteric fever in a high burden, resource-limited setting. Andrews JR, Prajapati KG, Eypper E, Shrestha P, Shakya M, Pathak KR, Joshi N, Tiwari P, Risal M, Koirala S, Karkey A, Dongol S, Wen S, Smith AB, Maru D, Basnyat B, Baker S, Farrar J, Ryan ET, Hohmann E, Arjyal A. PLoS Negl Trop Dis. 2013 Jun 27;7(6):e2292. doi: 10.1371/journal.pntd.0002292. Print 2013 Jun. PMID: 23853696
    176. Natural selection in a bangladeshi population from the cholera-endemic ganges river delta.  Karlsson EK, Harris JB, Tabrizi S, Rahman A, Shlyakhter I, Patterson N, O'Dushlaine C, Schaffner SF, Gupta S, Chowdhury F, Sheikh A, Shin OS, Ellis C, Becker CE, Stuart LM, Calderwood SB, Ryan ET, Qadri F, Sabeti PC, Larocque RC. Sci Transl Med. 2013 Jul 3;5(192):192ra86. doi: 10.1126/scitranslmed.3006338. PMID: 23825302
    177. Immune responses to the O-specific polysaccharide antigen in children who received a killed oral cholera vaccine compared to responses following natural cholera infection in Bangladesh.  Leung DT, Uddin T, Xu P, Aktar A, Johnson RA, Rahman MA, Alam MM, Bufano MK, Eckhoff G, Wu-Freeman Y, Yu Y, Sultana T, Khanam F, Saha A, Chowdhury F, Khan AI, Charles RC, Larocque RC, Harris JB, Calderwood SB, Kovác P, Qadri F, Ryan ET. Clin Vaccine Immunol. 2013 Jun;20(6):780-8. doi: 10.1128/CVI.00035-13. Epub 2013 Mar 20. PMID: 23515016
    178. Identification of in vivo-induced bacterial proteins during human infection with Salmonella enterica serotype Paratyphi A. Alam MM, Tsai LL, Rollins SM, Sheikh A, Khanam F, Bufano MK, Yu Y, Wu-Freeman Y, Kalsy A, Sultana T, Sayeed MA, Jahan N, LaRocque RC, Harris JB, Leung DT, Brooks WA, Calderwood SB, Charles RC, Qadri F, Ryan ET. Clin Vaccine Immunol. 2013 May;20(5):712-9. doi: 10.1128/CVI.00054-13. Epub 2013 Mar 13. PMID: 23486419
    179. Travel characteristics and yellow fever vaccine usage among US Global TravEpiNet travelers visiting countries with risk of yellow fever virus transmission, 2009-2011. Jentes ES, Han P, Gershman MD, Rao SR, LaRocque RC, Staples JE, Ryan ET; Global TravEpiNet Consortium. Am J Trop Med Hyg. 2013 May;88(5):954-61. doi: 10.4269/ajtmh.12-0463. Epub 2013 Mar 4. PMID: 23458961
    180. Non-typhoidal Salmonella gastroenteritis at a diarrheal hospital in Dhaka, Bangladesh, 1996-2011.Leung DT, Das SK, Malek MA, Ahmed D, Khanam F, Qadri F, Faruque AS, Ryan ET. Am J Trop Med Hyg. 2013 Apr;88(4):661-9. doi: 10.4269/ajtmh.12-0672. Epub 2013 Jan 28. PMID: 2335864
    181. Pre-travel health care of immigrants returning home to visit friends and relatives. LaRocque RC, Deshpande BR, Rao SR, Brunette GW, Sotir MJ, Jentes ES, Ryan ET; Global TravEpiNet Consortium. Am J Trop Med Hyg. 2013 Feb;88(2):376-80. doi: 10.4269/ajtmh.2012.12-0460. Epub 2012 Nov 13. Erratum in: Am J Trop Med Hyg. 2013 Mar;88(3):606. PMID: 23149585
    182. Study of avidity of antigen-specific antibody as a means of understanding development of long-term immunological memory after Vibrio cholerae O1 infection. Alam MM, Arifuzzaman M, Ahmad SM, Hosen MI, Rahman MA, Rashu R, Sheikh A, Ryan ET, Calderwood SB, Qadri F. Clin Vaccine Immunol. 2013 Jan;20(1):17-23. doi: 10.1128/CVI.00521-12. Epub 2012 Oct 31. PMID: 23114701
    183. Robust microarray production of freshly expressed proteins in a human milieu. Festa F, Rollins SM, Vattem K, Hathaway M, Lorenz P, Mendoza EA, Yu X, Qiu J, Kilmer G, Jensen P, Webb B, Ryan ET, LaBaer J. Proteomics Clin Appl. 2013 Jun;7(5-6):372-7. doi: 10.1002/prca.201200063. Epub 2013 May 17. PMID: 23027544
    184. Comparison of immune responses to the O-specific polysaccharide and lipopolysaccharide of Vibrio cholerae O1 in Bangladeshi adult patients with cholera. Johnson RA, Uddin T, Aktar A, Mohasin M, Alam MM, Chowdhury F, Harris JB, LaRocque RC, Bufano MK, Yu Y, Wu-Freeman Y, Leung DT, Sarracino D, Krastins B, Charles RC, Xu P, Kovác P, Calderwood SB, Qadri F, Ryan ET. Clin Vaccine Immunol. 2012 Nov;19(11):1712-21. doi: 10.1128/CVI.00321-12. Epub 2012 Sep 19. PMID: 22993410
    185. Frequency of reexposure to Vibrio cholerae O1 evaluated by subsequent vibriocidal titer rise after an episode of severe cholera in a highly endemic area in Bangladesh. Weil AA, Chowdhury F, Khan AI, Leung DT, Uddin T, Begum YA, Saha NC, Charles RC, Larocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB. Am J Trop Med Hyg. 2012 Nov;87(5):921-6. doi: 10.4269/ajtmh.2012.12-0323. Epub 2012 Sep 10. PMID: 22964723
    186. High depth, whole-genome sequencing of cholera isolates from Haiti and the Dominican Republic.Sealfon R, Gire S, Ellis C, Calderwood S, Qadri F, Hensley L, Kellis M, Ryan ET, LaRocque RC, Harris JB, Sabeti PC. BMC Genomics. 2012 Sep 11;13:468. doi: 10.1186/1471-2164-13-468. PMID: 22963323
    187. Cholera.  Harris JB, LaRocque RC, Qadri F, Ryan ET, Calderwood SB. Lancet. 2012 Jun 30;379(9835):2466-76. PMID: 22748592
    188. Antigen-specific memory T cell responses after vaccination with an oral killed cholera vaccine in Bangladeshi children and comparison with natural cholera. 
      Arifuzzaman M, Rashu R, Leung DT, Hosen MI, Bhuiyan TR, Bhuiyan MS, Rahman MA, Khanam F, Saha A, Charles RC, Larocque RC, Weil AA, Clements JD, Holmes RK, Calderwood SB, Harris JB, Ryan ET, Qadri F. Clin Vaccine Immunol. 2012 Jun 27. [Epub ahead of print] PMID: 22739692
    189. In the Clinic. Travel medicine.  Schwartz BS, Larocque RC, Ryan ET. Ann Intern Med. 2012 Jun 5;156(11):ITC61. PMID: 22665823
    190. Memory B cell responses to Vibrio cholerae O1 lipopolysaccharide are associated with protection against infection from household contacts of patients with cholera in Bangladesh.  Patel SM, Rahman MA, Mohasin M, Riyadh MA, Leung DT, Alam MM, Chowdhury F, Khan AI, Weil AA, Aktar A, Nazim M, LaRocque RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Clin Vaccine Immunol. 2012 Jun;19(6):842-8. Epub 2012 Apr 18. PMID: 22518009
    191. Immune responses to cholera in children.  Leung DT, Chowdhury F, Calderwood SB, Qadri F, Ryan ET. Expert Rev Anti Infect Ther. 2012 Apr;10(4):435-44. PMID: 22512753
    192. Factors associated with encephalopathy in patients with Salmonella enterica serotype Typhi bacteremia presenting to a diarrheal hospital in Dhaka, Bangladesh.  Leung DT, Bogetz J, Itoh M, Ganapathi L, Pietroni MA, Ryan ET, Chisti MJ. Am J Trop Med Hyg. 2012 Apr;86(4):698-702. PMID: 22492156
    193. Memory B cell and other immune responses in children receiving two doses of an oral killed cholera vaccine compared to responses following natural cholera infection in Bangladesh. 
      Leung DT, Rahman MA, Mohasin M, Patel SM, Aktar A, Khanam F, Uddin T, Riyadh MA, Saha A, Alam MM, Chowdhury F, Khan AI, Charles R, LaRocque R, Harris JB, Calderwood SB, Qadri F, Ryan ET. Clin Vaccine Immunol. 2012 May;19(5):690-8. Epub 2012 Mar 21. PMID: 22441386
    194. Transcutaneous immunization with a Vibrio cholerae O1 Ogawa synthetic hexasaccharide conjugate following oral whole-cell cholera vaccination boosts vibriocidal responses and induces protective immunity in mice.  Tarique AA, Kalsy A, Arifuzzaman M, Rollins SM, Charles RC, Leung DT, Harris JB, Larocque RC, Sheikh A, Bhuiyan MS, Saksena R, Clements JD, Calderwood SB, Qadri F, Kovác P, Ryan ET. Clin Vaccine Immunol. 2012 Apr;19(4):594-602. Epub 2012 Feb 22. PMID: 22357651
    195. Systemic antibody responses to the immunodominant p23 antigen and p23 polymorphisms in children with cryptosporidiosis in Bangladesh.  Borad AJ, Allison GM, Wang D, Ahmed S, Karim MM, Kane AV, Moy J, Hibberd PL, Ajjampur SS, Kang G, Calderwood SB, Ryan ET, Naumova E, Khan WA, Ward HD. Am J Trop Med Hyg. 2012 Feb;86(2):214-22. PMID: 22302851
    196. Individuals with Le(a+b-) blood group have increased susceptibility to symptomatic vibrio cholerae O1 infection.  Arifuzzaman M, Ahmed T, Rahman MA, Chowdhury F, Rashu R, Khan AI, LaRocque RC, Harris JB, Bhuiyan TR, Ryan ET, Calderwood SB, Qadri F. PLoS Negl Trop Dis. 2011 Dec;5(12):e1413. doi: 10.1371/journal.pntd.0001413. Epub 2011 Dec 27. PMID: 22216364 Free PMC Article
    197. Haiti in the context of the current global cholera pandemic.  Ryan ET. Emerg Infect Dis. 2011 Nov;17(11):2175-6. PMID: 22204041 Free PMC Article
    198. In vivo expression of Salmonella enterica serotype Typhi genes in the blood of patients with typhoid fever in Bangladesh.  Sheikh A, Charles RC, Sharmeen N, Rollins SM, Harris JB, Bhuiyan MS, Arifuzzaman M, Khanam F, Bukka A, Kalsy A, Porwollik S, Leung DT, Brooks WA, LaRocque RC, Hohmann EL, Cravioto A, Logvinenko T, Calderwood SB, McClelland M, Graham JE, Qadri F, Ryan ET. PLoS Negl Trop Dis. 2011 Dec;5(12):e1419. Epub 2011 Dec 13. PMID: 22180799 Free PMC Article
    199. Case records of the Massachusetts General Hospital. Case 38-2011. A 34-year-old man with diarrhea and weakness.  Ryan ET, Cronin CG, Branda JA. N Engl J Med. 2011 Dec 15;365(24):2306-16. PMID: 22168646
    200. Global TravEpiNet: a national consortium of clinics providing care to international travelers--analysis of demographic characteristics, travel destinations, and pretravel healthcare of high-risk US international travelers, 2009-2011.  LaRocque RC, Rao SR, Lee J, Ansdell V, Yates JA, Schwartz BS, Knouse M, Cahill J, Hagmann S, Vinetz J, Connor BA, Goad JA, Oladele A, Alvarez S, Stauffer W, Walker P, Kozarsky P, Franco-Paredes C, Dismukes R, Rosen J, Hynes NA, Jacquerioz F, McLellan S, Hale D, Sofarelli T, Schoenfeld D, Marano N, Brunette G, Jentes ES, Yanni E, Sotir MJ, Ryan ET; Global TravEpiNet Consortium. Clin Infect Dis. 2012 Feb 15;54(4):455-62. Epub 2011 Dec 5. PMID: 22144534
    201. LPLUNC1 modulates innate immune responses to Vibrio cholerae.  Shin OS, Uddin T, Citorik R, Wang JP, Della Pelle P, Kradin RL, Bingle CD, Bingle L, Camilli A, Bhuiyan TR, Shirin T, Ryan ET, Calderwood SB, Finberg RW, Qadri F, Larocque RC, Harris JB. J Infect Dis. 2011 Nov;204(9):1349-57. Epub 2011 Sep 7. PMID: 21900486
    202. Simple, direct conjugation of bacterial O-SP-core antigens to proteins: development of cholera conjugate vaccines.  Xu P, Alam MM, Kalsy A, Charles RC, Calderwood SB, Qadri F, Ryan ET, Kováč P. Bioconjug Chem. 2011 Oct 19;22(10):2179-85. Epub 2011 Sep 30. PMID: 21899371
    203. Cholera in the 21st century.  Charles RC, Ryan ET. Curr Opin Infect Dis. 2011 Oct;24(5):472-7. Review. PMID: 21799407
    204. Antibody responses to the immunodominant Cryptosporidium gp15 antigen and gp15 polymorphisms in a case-control study of cryptosporidiosis in children in Bangladesh.  Allison GM, Rogers KA, Borad A, Ahmed S, Karim MM, Kane AV, Hibberd PL, Naumova EN, Calderwood SB, Ryan ET, Khan WA, Ward HD. Am J Trop Med Hyg. 2011 Jul;85(1):97-104. PMID: 21734132 Free PMC Article
    205. Case records of the Massachusetts General Hospital. Case 20-2011. A 30-year-old man with diarrhea after a trip to the Dominican Republic. Ryan ET, Madoff LC, Ferraro MJ. N Engl J Med. 2011 Jun 30;364(26):2536-41. PMID: 21714651
    206. Vibrio cholerae O1 infection induces proinflammatory CD4+ T-cell responses in blood and intestinal mucosa of infected humans.  Kuchta A, Rahman T, Sennott EL, Bhuyian TR, Uddin T, Rashu R, Chowdhury F, Kahn AI, Arifuzzaman M, Weil AA, Podolsky M, LaRocque RC, Ryan ET, Calderwood SB, Qadri F, Harris JB. Clin Vaccine Immunol. 2011 Aug;18(8):1371-7. Epub 2011 Jun 22. PMID: 21697339 Free PMC Article
    207. Comparison of memory B cell, antibody-secreting cell, and plasma antibody responses in young children, older children, and adults with infection caused by Vibrio cholerae O1 El Tor Ogawa in Bangladesh.  Leung DT, Rahman MA, Mohasin M, Riyadh MA, Patel SM, Alam MM, Chowdhury F, Khan AI, Kalivoda EJ, Aktar A, Bhuiyan MS, LaRocque RC, Harris JB, Calderwood SB, Qadri F, Ryan ET. Clin Vaccine Immunol. 2011 Aug;18(8):1317-25. Epub 2011 Jun 22. PMID: 21697337 Free PMC Article
    208. Interferon-γ and proliferation responses to Salmonella enterica Serotype Typhi proteins in patients with S. Typhi Bacteremia in Dhaka, Bangladesh.  Sheikh A, Khanam F, Sayeed MA, Rahman T, Pacek M, Hu Y, Rollins A, Bhuiyan MS, Rollins S, Kalsy A, Arifuzzaman M, Leung DT, Sarracino DA, Krastins B, Charles RC, Larocque RC, Cravioto A, Calderwood SB, Brooks WA, Harris JB, Labaer J, Qadri F, Ryan ET. PLoS Negl Trop Dis. 2011 Jun;5(6):e1193. Epub 2011 Jun 7. PMID: 21666798 Free PMC Article
    209. Meeting cholera's challenge to Haiti and the world: a joint statement on cholera prevention and care.  Farmer P, Almazor CP, Bahnsen ET, Barry D, Bazile J, Bloom BR, Bose N, Brewer T, Calderwood SB, Clemens JD, Cravioto A, Eustache E, Jérôme G, Gupta N, Harris JB, Hiatt HH, Holstein C, Hotez PJ, Ivers LC, Kerry VB, Koenig SP, Larocque RC, Léandre F, Lambert W, Lyon E, Mekalanos JJ, Mukherjee JS, Oswald C, Pape JW, Gretchko Prosper A, Rabinovich R, Raymonville M, Réjouit JR, Ronan LJ, Rosenberg ML, Ryan ET, Sachs JD, Sack DA, Surena C, Suri AA, Ternier R, Waldor MK, Walton D, Weigel JL. PLoS Negl Trop Dis. 2011;5(5):e1145. Epub 2011 May 31. Review. PMID: 21655350 Free PMC Article
    210. Genetic diversity of Cryptosporidium spp. from Bangladeshi children. Hira KG, Mackay MR, Hempstead AD, Ahmed S, Karim MM, O'Connor RM, Hibberd PL, Calderwood SB, Ryan ET, Khan WA, Ward HD. J Clin Microbiol. 2011 Jun;49(6):2307-10. Epub 2011 Apr 6. PMID: 21471344 Free PMC Article
    211. Antigen-specific memory B-cell responses in Bangladeshi adults after one or two dose oral killed cholera vaccination, and comparison with responses following natural cholera.
      Alam MM, Riyadh MA, Fatema K, Rahman MA, Akhtar N, Ahmed T, Chowdhury MI, Chowdhury F, Calderwood SB, Harris JB, Ryan ET, Qadri F.Clin Vaccine Immunol. 2011 Feb 23. [Epub ahead of print] PMID: 21346055
    212. The cholera pandemic, still with us after half a century: time to rethink. Ryan ET. PLoS Negl Trop Dis. 2011 Jan 25;5(1):e1003.  PMID: 21283611
    213. Mucosal immunologic responses in cholera patients in bangladesh. Uddin T, Harris JB, Bhuiyan TR, Shirin T, Uddin MI, Khan AI, Chowdhury F, Larocque RC, Alam NH, Ryan ET, Calderwood SB, Qadri F.Clin Vaccine Immunol. 2011 Mar;18(3):506-12. Epub 2011 Jan 19. PMID: 21248157
    214. Severe, acute watery diarrhea in an adult. Chowdhury F, Khan AI, Faruque AS, Ryan ET. PLoS Negl Trop Dis. 2010 Nov 30;4(11):e898.  PMID: 21152053
    215. Analysis of Salmonella enterica serotype paratyphi A gene expression in the blood of bacteremic patients in Bangladesh. Sheikh A, Charles RC, Rollins SM, Harris JB, Bhuiyan MS, Khanam F, Bukka A, Kalsy A, Porwollik S, Brooks WA, LaRocque RC, Hohmann EL, Cravioto A, Logvinenko T, Calderwood SB, McClelland M, Graham JE, Qadri F, Ryan ET. PLoS Negl Trop Dis. 2010 Dec 7;4(12):e908. PMID: 21151879
    216. Relatedness of Vibrio cholerae O1/O139 isolates from patients and their household contacts, determined by multilocus variable-number tandem-repeat analysis. Kendall EA, Chowdhury F, Begum Y, Khan AI, Li S, Thierer JH, Bailey J, Kreisel K, Tacket CO, LaRocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB, Stine OC. J Bacteriol. 2010 Sep;192(17):4367-76. Epub 2010 Jun 28. PMID: 20585059
    217. Characterization of anti-Salmonella enterica serotype Typhi antibody responses in bacteremic Bangladeshi patients by an immunoaffinity proteomics-based technology. Charles RC, Sheikh A, Krastins B, Harris JB, Bhuiyan MS, LaRocque RC, Logvinenko T, Sarracino DA, Kudva IT, Eisenstein J, Podolsky MJ, Kalsy A, Brooks WA, Ludwig A, John M, Calderwood SB, Qadri F, Ryan ET.Clin Vaccine Immunol. 2010 Aug;17(8):1188-95. Epub 2010 Jun 23. PMID: 20573880
    218. Informal urban settlements and cholera risk in Dar es Salaam, Tanzania. Penrose K, de Castro MC, Werema J, Ryan ET.PLoS Negl Trop Dis. 2010 Mar 16;4(3):e631. PMID: 20300569
    219. Concomitant enterotoxigenic Escherichia coli infection induces increased immune responses to Vibrio cholerae O1 antigens in patients with cholera in Bangladesh.
      Chowdhury F, Begum YA, Alam MM, Khan AI, Ahmed T, Bhuiyan MS, Harris JB, LaRocque RC, Faruque AS, Endtz H, Ryan ET, Cravioto A, Svennerholm AM, Calderwood SB, Qadri F. Infect Immun. 2010 May;78(5):2117-24. Epub 2010 Feb 22. PMID: 20176796
    220. Familial aggregation of Vibrio cholerae-associated infection in Matlab, Bangladesh.
      Rahman KM, Duggal P, Harris JB, Saha SK, Streatfield PK, Ryan ET, Calderwood SB, Qadri F, Yunus M, LaRocque RC.J Health Popul Nutr. 2009 Dec;27(6):733-8. PMID: 20099756
    221. Comparison of clinical features and immunological parameters of patients with dehydrating diarrhoea infected with Inaba or Ogawa serotypes of Vibrio cholerae O1. Khan AI, Chowdhury F, Harris JB, Larocque RC, Faruque AS, Ryan ET, Calderwood SB, Qadri F. Scand J Infect Dis. 2009 Nov 2. PMID: 19883159
    222. Development of IgM memory to both a T cell-independent and a T cell-dependent antigen following infection with Vibrio cholerae O1 in Bangladesh. Kendall EA, Tarique AA, Hossain A, Alam MM, Arifuzzaman M, Akhtar N, Chowdhury F, Khan AI, Larocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB.
      Infect Immun. 2009 Oct 26. PMID: 19858296
    223. Clinical outcomes in household contacts of patients with cholera in bangladesh. Weil AA, Khan AI, Chowdhury F, Larocque RC, Faruque AS, Ryan ET, Calderwood SB, Qadri F, Harris JB. Clin Infect Dis. 2009 Nov 15;49(10):1473-9.PMID: 19842974
    224. Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium. Charles RC, Harris JB, Chase MR, Lebrun LM, Sheikh A, LaRocque RC, Logvinenko T, Rollins SM, Tarique A, Hohmann EL, Rosenberg I, Krastins B, Sarracino DA, Qadri F, Calderwood SB, Ryan ET. PLoS One. 2009 Sep 10;4(9):e6994.PMID: 19746165 Free article
    225. Salmonella enterica serovar Typhi-specific immunoglobulin A antibody responses in plasma and antibody in lymphocyte supernatant specimens in Bangladeshi patients with suspected typhoid fever. Sheikh A, Bhuiyan MS, Khanam F, Chowdhury F, Saha A, Ahmed D, Jamil KM, LaRocque RC, Harris JB, Ahmad MM, Charles R, Brooks WA, Calderwood SB, Cravioto A, Ryan ET, Qadri F. Clin Vaccine Immunol. 2009 Nov;16(11):1587-94. Epub 2009 Sep 9.PMID: 19741090
    226. Memory T-cell responses to Vibrio cholerae O1 infection. Weil AA, Arifuzzaman M, Bhuiyan TR, LaRocque RC, Harris AM, Kendall EA, Hossain A, Tarique AA, Sheikh A, Chowdhury F, Khan AI, Murshed F, Parker KC, Banerjee KK, Ryan ET, Harris JB, Qadri F, Calderwood SB. Infect Immun. 2009 Nov;77(11):5090-6. Epub 2009 Aug 24.PMID: 19703973
    227. Vaccination of children in low-resource countries against Shigella is unlikely to present an undue risk of reactive arthritis. Gaston JS, Inman RD, Ryan ET, Venkatesan MM, Barry EM, Hale TL, Bourgeois AL, Walker RI. Vaccine. 2009 Sep 4;27(40):5432-4. Epub 2009 Jul 28.PMID:
    228. Transcutaneous immunization with a synthetic hexasaccharide-protein conjugate induces anti-Vibrio cholerae lipopolysaccharide responses in mice. Rollenhagen JE, Kalsy A, Saksena R, Sheikh A, Alam MM, Qadri F, Calderwood SB, Kovác P, Ryan ET. Vaccine. 2009 Aug 6;27(36):4917-22. Epub 2009 Jun 27.PMID: 19563890
    229. Antigen-specific memory B-cell responses to Vibrio cholerae O1 infection in Bangladesh. Harris AM, Bhuiyan MS, Chowdhury F, Khan AI, Hossain A, Kendall EA, Rahman A, LaRocque RC, Wrammert J, Ryan ET, Qadri F, Calderwood SB, Harris JB.
      Infect Immun. 2009 Sep;77(9):3850-6. Epub 2009 Jun 15.PMID: 19528207
    230. Immunologic Responses to Vibrio cholerae in Patients Co-Infected with Intestinal Parasites in Bangladesh. Harris JB, Podolsky MJ, Bhuiyan TR, Chowdhury F, Khan AI, Larocque RC, Logvinenko T, Kendall J, Faruque AS, Nagler CR, Ryan ET, Qadri F, Calderwood SB. PLoS Negl Trop Dis. 2009;3(3):e403. Epub 2009 Mar 31.PMID: 19333369 Free article
    231. A variant in long palate, lung and nasal epithelium clone 1 is associated with cholera in a Bangladeshi population. Larocque RC, Sabeti P, Duggal P, Chowdhury F, Khan AI, Lebrun LM, Harris JB, Ryan ET, Qadri F, Calderwood SB. Genes Immun. 2009 Apr;10(3):267-72. Epub 2009 Feb 12.PMID: 19212328 Free article
    232. Shifting prevalence of major diarrheal pathogens in patients seeking hospital care during floods in 1998, 2004, and 2007 in Dhaka, Bangladesh.
      Harris AM, Chowdhury F, Begum YA, Khan AI, Faruque AS, Svennerholm AM, Harris JB, Ryan ET, Cravioto A, Calderwood SB, Qadri F. Am J Trop Med Hyg. 2008 Nov;79(5):708-14.PMID: 18981509 Free article
    233. Management of travellers' diarrhoea. Hill DR, Ryan ET. BMJ. 2008 Oct 6;337:a1746. doi: 10.1136/bmj.a1746. Review. PMID: 18838421
    234. A comparison of clinical and immunologic features in children and older patients hospitalized with severe cholera in Bangladesh.
      Chowdhury F, Khan AI, Harris JB, LaRocque RC, Chowdhury MI, Ryan ET, Faruque AS, Calderwood SB, Qadri F. Pediatr Infect Dis J. 2008 Nov;27(11):986-92.PMID: 18833030 Free article
    235. Cholera toxin-specific memory B cell responses are induced in patients with dehydrating diarrhea caused by Vibrio cholerae O1. Jayasekera CR, Harris JB, Bhuiyan S, Chowdhury F, Khan AI, Faruque AS, Larocque RC, Ryan ET, Ahmed R, Qadri F, Calderwood SB. J Infect Dis. 2008 Oct 1;198(7):1055-61.PMID: 18729782 Free article
    236. Proteomic analysis of Vibrio cholerae in human stool. LaRocque RC, Krastins B, Harris JB, Lebrun LM, Parker KC, Chase M, Ryan ET, Qadri F, Sarracino D, Calderwood SB. Infect Immun. 2008 Sep;76(9):4145-51. Epub 2008 Jun 30.PMID: 18591230 Free article
    237. Susceptibility to Vibrio cholerae Infection in a Cohort of Household Contacts of Patients with Cholera in Bangladesh. Harris JB, Larocque RC, Chowdhury F, Khan AI, Logvinenko T, Faruque AS, Ryan ET, Qadri F, Calderwood SB. PLoS Negl Trop Dis. 2008 Apr 9;2(4):e221.PMID: 18398491 Free article
    238. Application of in vivo induced antigen technology (IVIAT) to Bacillus anthracis. Rollins SM, Peppercorn A, Young JS, Drysdale M, Baresch A, Bikowski MV, Ashford DA, Quinn CP, Handfield M, Hillman JD, Lyons CR, Koehler TM, Calderwood SB, Ryan ET. PLoS One. 2008 Mar 19;3(3):e1824.PMID: 18350160 Free article
    239. Complexity of rice-water stool from patients with Vibrio cholerae plays a role in the transmission of infectious diarrhea. Nelson EJ, Chowdhury A, Harris JB, Begum YA, Chowdhury F, Khan AI, Larocque RC, Bishop AL, Ryan ET, Camilli A, Qadri F, Calderwood SB. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19091-6. Epub 2007 Nov 16.PMID: 18024592 Free article
    240. Case records of the Massachusetts General Hospital. Case 29-2007. A 51-year-old man with gastric cancer and lung nodules. Ryan ET, Aquino SL, Kradin RL. N Engl J Med. 2007 Sep 20;357(12):1239-46. PMID: 17881756
    241. Bacteremia, fever, and splenomegaly caused by a newly recognized bartonella species. Eremeeva ME, Gerns HL, Lydy SL, Goo JS, Ryan ET, Mathew SS, Ferraro MJ, Holden JM, Nicholson WL, Dasch GA, Koehler JE.
      N Engl J Med. 2007 Jun 7;356(23):2381-7.PMID: 17554119 Free article
    242. Transcutaneous immunization with Clostridium difficile toxoid A induces systemic and mucosal immune responses and toxin A-neutralizing antibodies in mice. Ghose C, Kalsy A, Sheikh A, Rollenhagen J, John M, Young J, Rollins SM, Qadri F, Calderwood SB, Kelly CP, Ryan ET. Infect Immun. 2007 Jun;75(6):2826-32. Epub 2007 Mar 19.PMID: 17371854 Free article
    243. The practice of travel medicine: guidelines by the Infectious Diseases Society of America. Hill DR, Ericsson CD, Pearson RD, Keystone JS, Freedman DO, Kozarsky PE, DuPont HL, Bia FJ, Fischer PR, Ryan ET; Infectious Diseases Society of America. Clin Infect Dis. 2006 Dec 15;43(12):1499-539. Epub 2006 Nov 8. PMID: 17109284
    244. Live attenuated oral cholera vaccines. Ryan ET, Calderwood SB, Qadri F.
      Expert Rev Vaccines. 2006 Aug;5(4):483-94. Review.PMID: 16989629
    245. Transcutaneous immunization with toxin-coregulated pilin A induces protective immunity against Vibrio cholerae O1 El Tor challenge in mice. Rollenhagen JE, Kalsy A, Cerda F, John M, Harris JB, Larocque RC, Qadri F, Calderwood SB, Taylor RK, Ryan ET. Infect Immun. 2006 Oct;74(10):5834-9.PMID: 16988262 Free article
    246. Primaquine: report from CDC expert meeting on malaria chemoprophylaxis I. Hill DR, Baird JK, Parise ME, Lewis LS, Ryan ET, Magill AJ. Am J Trop Med Hyg. 2006 Sep;75(3):402-15.PMID: 16968913 Free article
    247. Infectious diseases of severe weather-related and flood-related natural disasters. Ivers LC, Ryan ET. Curr Opin Infect Dis. 2006 Oct;19(5):408-14. Review.PMID: 16940862
    248. Identification of in vivo-induced bacterial protein antigens during human infection with Salmonella enterica serovar Typhi. Harris JB, Baresch-Bernal A, Rollins SM, Alam A, LaRocque RC, Bikowski M, Peppercorn AF, Handfield M, Hillman JD, Qadri F, Calderwood SB, Hohmann E, Breiman RF, Brooks WA, Ryan ET. Infect Immun. 2006 Sep;74(9):5161-8.PMID: 16926408 Free article
    249. Postgenomic approaches to cholera vaccine development. LaRocque RC, Harris JB, Ryan ET, Qadri F, Calderwood SB. Expert Rev Vaccines. 2006 Jun;5(3):337-46. Review.PMID: 16827618
    250. Diarrheal epidemics in Dhaka, Bangladesh, during three consecutive floods: 1988, 1998, and 2004.Schwartz BS, Harris JB, Khan AI, Larocque RC, Sack DA, Malek MA, Faruque AS, Qadri F, Calderwood SB, Luby SP, Ryan ET.
      Am J Trop Med Hyg. 2006 Jun;74(6):1067-73.PMID: 16760521 Free article
    251. Low risk of hemolytic uremic syndrome after early effective antimicrobial therapy for Shigella dysenteriae type 1 infection in Bangladesh. Bennish ML, Khan WA, Begum M, Bridges EA, Ahmed S, Saha D, Salam MA, Acheson D, Ryan ET. Clin Infect Dis. 2006 Feb 1;42(3):356-62. Epub 2005 Dec 21.PMID: 16392080
    252. Case records of the Massachusetts General Hospital. Case 39-2005. A 63-year-old woman with a positive serologic test for syphilis and persistent eosinophilia. Ryan ET, Felsenstein D, Aquino SL, Branda JA, Morgan JG. N Engl J Med. 2005 Dec 22;353(25):2697-705. PMID: 16371636
    253. Blood group, immunity, and risk of infection with Vibrio cholerae in an area of endemicity. Harris JB, Khan AI, LaRocque RC, Dorer DJ, Chowdhury F, Faruque AS, Sack DA, Ryan ET, Qadri F, Calderwood SB. Infect Immun. 2005 Nov;73(11):7422-7.PMID: 16239542 Free article
    254. Hyperinfectivity of human-passaged Vibrio cholerae can be modeled by growth in the infant mouse.Alam A, Larocque RC, Harris JB, Vanderspurt C, Ryan ET, Qadri F, Calderwood SB. Infect Immun. 2005 Oct;73(10):6674-9.PMID: 16177344 Free article
    255. Reduction in capsular content and enhanced bacterial susceptibility to serum killing of Vibrio cholerae O139 associated with the 2002 cholera epidemic in Bangladesh. Qadri F, Svennerholm AM, Shamsuzzaman S, Bhuiyan TR, Harris JB, Ghosh AN, Nair GB, Weintraub A, Faruque SM, Ryan ET, Sack DA, Calderwood SB. Infect Immun. 2005 Oct;73(10):6577-83.PMID: 16177333 Free article
    256. Species-specific bacteria identification using differential mobility spectrometry and bioinformatics pattern recognition. Shnayderman M, Mansfield B, Yip P, Clark HA, Krebs MD, Cohen SJ, Zeskind JE, Ryan ET, Dorkin HL, Callahan MV, Stair TO, Gelfand JA, Gill CJ, Hitt B, Davis CE. Anal Chem. 2005 Sep 15;77(18):5930-7.PMID: 16159124
    257. Transcriptional profiling of Vibrio cholerae recovered directly from patient specimens during early and late stages of human infection. Larocque RC, Harris JB, Dziejman M, Li X, Khan AI, Faruque AS, Faruque SM, Nair GB, Ryan ET, Qadri F, Mekalanos JJ, Calderwood SB. Infect Immun. 2005 Aug;73(8):4488-93.PMID: 16040959 Free article
    258. Transformation of the developing world: socioeconomic matrix. Carroll D, Gardner P, Kay BA, Osterholm M, Ryan ET. Emerg Infect Dis. 2004 Nov;10(11):2049. PMID: 16010742
    259. Case records of the Massachusetts General Hospital. Case 19-2005. A 17-year-old girl with respiratory distress and hemiparesis after surviving a tsunami. Kao AY, Munandar R, Ferrara SL, Systrom DM, Sheridan RL, Cash SS, Ryan ET. N Engl J Med. 2005 Jun 23;352(25):2628-36. PMID: 15972870
    260. Prevention of infection in adult travelers after solid organ transplantation. Kotton CN, Ryan ET, Fishman JA. Am J Transplant. 2005 Jan;5(1):8-14. Review.PMID: 15636606
    261. In vivo induced antigen technology (IVIAT). Rollins SM, Peppercorn A, Hang L, Hillman JD, Calderwood SB, Handfield M, Ryan ET. Cell Microbiol. 2005 Jan;7(1):1-9. Review.PMID: 15617518
    262. Cryptosporidiosis among Bangladeshi children with diarrhea: a prospective, matched, case-control study of clinical features, epidemiology and systemic antibody responses. Khan WA, Rogers KA, Karim MM, Ahmed S, Hibberd PL, Calderwood SB, Ryan ET, Ward HD. Am J Trop Med Hyg. 2004 Oct;71(4):412-9.PMID: 15516636 Free article
    263. The major subunit of the toxin-coregulated pilus TcpA induces mucosal and systemic immunoglobulin A immune responses in patients with cholera caused by Vibrio cholerae O1 and O139. Asaduzzaman M, Ryan ET, John M, Hang L, Khan AI, Faruque AS, Taylor RK, Calderwood SB, Qadri F. Infect Immun. 2004 Aug;72(8):4448-54.PMID: 15271902 Free article
    264. Incomplete correlation of serum vibriocidal antibody titer with protection from Vibrio cholerae infection in urban Bangladesh. Saha D, LaRocque RC, Khan AI, Harris JB, Begum YA, Akramuzzaman SM, Faruque AS, Ryan ET, Qadri F, Calderwood SB. J Infect Dis. 2004 Jun 15;189(12):2318-22. Epub 2004 May 25.PMID: 15181581
    265. Medical problems in the returning expatriate. Hochberg N, Ryan ET. Clin Occup Environ Med. 2004 Feb;4(1):205-19. Review.PMID: 15043371
    266. Vaccination strategies. Ivers LC, Ryan ET. Clin Occup Environ Med. 2004 Feb;4(1):27-43.PMID: 15043362
    267. Yersinia pestis and the plague. Rollins SE, Rollins SM, Ryan ET. Am J Clin Pathol. 2003 Jun;119 Suppl:S78-85. Review.PMID: 12951845
    268. Antigen-specific immunoglobulin A antibodies secreted from circulating B cells are an effective marker for recent local immune responses in patients with cholera: comparison to antibody-secreting cell responses and other immunological markers. Qadri F, Ryan ET, Faruque AS, Ahmed F, Khan AI, Islam MM, Akramuzzaman SM, Sack DA, Calderwood SB. Infect Immun. 2003 Aug;71(8):4808-14.PMID: 12874365 Free article
    269. Use of in vivo-induced antigen technology (IVIAT) to identify genes uniquely expressed during human infection with Vibrio cholerae. Hang L, John M, Asaduzzaman M, Bridges EA, Vanderspurt C, Kirn TJ, Taylor RK, Hillman JD, Progulske-Fox A, Handfield M, Ryan ET, Calderwood SB. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8508-13. Epub 2003 Jun 25.PMID: 12826608 Free article
    270. Images in clinical medicine. Thoracic echinococcosis. Brainard DM, Ryan ET. N Engl J Med. 2003 Feb 6;348(6):528. PMID: 12571260
    271. Illness after international travel. Ryan ET, Wilson ME, Kain KC. N Engl J Med. 2002 Aug 15;347(7):505-16. Review. PMID: 12181406
    272. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-2002. A 37-year-old man with fever, hepatosplenomegaly, and a cutaneous foot lesion after a trip to Africa.Moore AC, Ryan ET, Waldron MA. N Engl J Med. 2002 Jun 27;346(26):2069-76. PMID: 12087144
    273. Comparison of mucosal and systemic humoral immune responses after transcutaneous and oral immunization strategies. John M, Bridges EA, Miller AO, Calderwood SB, Ryan ET. Vaccine. 2002 Jun 21;20(21-22):2720-6.PMID: 12034098
    274. Malaria: epidemiology, pathogenesis, diagnosis, prevention, and treatment--an update. Ryan ET. Curr Clin Top Infect Dis. 2001;21:83-113. Review. PMID: 11572163
    275. Local production of anti-vibrio cholerae mucosal antibody in reproductive tract tissues after cholera.Ryan ET, Bridges EA, Crean TI, Gausia K, Hamadani JD, Aziz A, Hawkes S, Begum M, Bogaerts J, Faruque SM, Salam MA, Fuchs GJ, Calderwood SB. J Infect Dis. 2001 Sep 1;184(5):643-7. Epub 2001 Aug 9.PMID: 11494170
    276. Mortality, morbidity, and microbiology of endemic cholera among hospitalized patients in Dhaka, Bangladesh. Ryan ET, Dhar U, Khan WA, Salam MA, Faruque AS, Fuchs GJ, Calderwood SB, Bennish ML. Am J Trop Med Hyg. 2000 Jul-Aug;63(1-2):12-20.PMID: 11357989 Free article
    277. Cholera vaccines. Ryan ET, Calderwood SB. J Travel Med. 2001 Mar-Apr;8(2):82-91. Review. PMID: 11285167
    278. Clostridium difficile--Associated diarrhea: A review. Mylonakis E, Ryan ET, Calderwood SB. Arch Intern Med. 2001 Feb 26;161(4):525-33. Review.PMID: 11252111 Free article
    279. Cholera vaccines. Ryan ET, Calderwood SB. Clin Infect Dis. 2000 Aug;31(2):561-5. Epub 2000 Sep 7. Review.PMID: 10987721
    280. Health advice and immunizations for travelers. Ryan ET, Kain KC. N Engl J Med. 2000 Jun 8;342(23):1716-25. Review. PMID: 10841875
    281. In vitro and in vivo analyses of constitutive and in vivo-induced promoters in attenuated vaccine and vector strains of Vibrio cholerae. John M, Crean TI, Calderwood SB, Ryan ET. Infect Immun. 2000 Mar;68(3):1171-5.PMID: 10678922 Free article
    282. Optimizing the germfree mouse model for in vivo evaluation of oral Vibrio cholerae vaccine and vector strains. Crean TI, John M, Calderwood SB, Ryan ET. Infect Immun. 2000 Feb;68(2):977-81.PMID: 10639476 Free article
    283. Development of a DeltaglnA balanced lethal plasmid system for expression of heterologous antigens by attenuated vaccine vector strains of Vibrio cholerae. Ryan ET, Crean TI, Kochi SK, John M, Luciano AA, Killeen KP, Klose KE, Calderwood SB. Infect Immun. 2000 Jan;68(1):221-6.PMID: 10603391 Free article
    284. In vivo expression and immunoadjuvancy of a mutant of heat-labile enterotoxin of Escherichia coli in vaccine and vector strains of Vibrio cholerae. Ryan ET, Crean TI, John M, Butterton JR, Clements JD, Calderwood SB. Infect Immun. 1999 Apr;67(4):1694-701.PMID: 10085006 Free article
    285. Oral immunization with attenuated vaccine strains of Vibrio cholerae expressing a dodecapeptide repeat of the serine-rich Entamoeba histolytica protein fused to the cholera toxin B subunit induces systemic and mucosal antiamebic and anti-V. cholerae antibody responses in mice. Ryan ET, Butterton JR, Zhang T, Baker MA, Stanley SL Jr, Calderwood SB. Infect Immun. 1997 Aug;65(8):3118-25.PMID: 9234763 Free article
    286. Protective immunity against Clostridium difficile toxin A induced by oral immunization with a live, attenuated Vibrio cholerae vector strain. Ryan ET, Butterton JR, Smith RN, Carroll PA, Crean TI, Calderwood SB. Infect Immun. 1997 Jul;65(7):2941-9.PMID: 9199470 Free article
    287. Coexpression of the B subunit of Shiga toxin 1 and EaeA from enterohemorrhagic Escherichia coli in Vibrio cholerae vaccine strains. Butterton JR, Ryan ET, Acheson DW, Calderwood SB. Infect Immun. 1997 Jun;65(6):2127-35.PMID: 9169742 Free article
    288. Development of a germfree mouse model of Vibrio cholerae infection. Butterton JR, Ryan ET, Shahin RA, Calderwood SB. Infect Immun. 1996 Oct;64(10):4373-7.PMID: 8926115 Free article
    289. Parasitic infections of the anterior segment. Young JA, Ryan ET. Int Ophthalmol Clin. 1996 Summer;36(3):49-71. Review. PMID: 8989600
    290. Myocardial infarction mimicked by acute cholecystitis. Ryan ET, Pak PH, DeSanctis RW. Ann Intern Med. 1992 Feb 1;116(3):218-20. PMID: 1728205
    291. Hirschsprung's disease: associated abnormalities and demography. Ryan ET, Ecker JL, Christakis NA, Folkman J. J Pediatr Surg. 1992 Jan;27(1):76-81.PMID: 1552451
    292. Polyclonal B-cell lymphocytosis and hypergammaglobulinemia in patients with Gaucher disease. Marti GE, Ryan ET, Papadopoulos NM, Filling-Katz M, Barton N, Fleischer TA, Rick M, Gralnick HR. Am J Hematol. 1988 Dec;29(4):189-94.PMID: 3263798
    Reviews, Chapters, and Editorials
    1. Ryan ET. Surgical nosocomial infections.  Resident Staff Phys 1991;2:11-15.
    2. Hibberd PL, Ryan ET, Baker AS.  Pneumocystis carinii, parasitic infections, and the eye.
      In:  Albert DM, Jakobiec FA, eds.  Principles and Practice of Ophthalmology. Philadelphia: WB Saunders; 1994. p. 3065-3077.
    3. Ryan ET, Baker AS.  Systemic bacterial infections and the eye.  In: Albert DM, Jakobiec FA, eds.  Principles and Practice of Ophthalmology.  Philadelphia:  WB Saunders; 1994. p. 3006-3010.
    4. Ryan ET, Swartz MN,  Dermatological infections. In:  Roitt IM, Delves PJ, eds.  Encyclopedia of Immunology, Second Edition.  London:  Academic Press Ltd.; 1998. p. 750-754.
    5. Ryan ET.  Ocular disease. In:  Guerrant RL, Walker DH, Weller PF, eds.  Tropical Infectious Diseases: Principles, Pathogens, and Practice.  Philadelphia  Churchill Livingstone; 1999. p. 1485-1541. (Textbook & pocket manual).
    6. Ryan ET, Maguire JH.  Parasitic infections and the eye. In:  Albert DM, Jakobiec FA, eds.  Principles and Practice of Ophthalmology.  Philadelphia:  WB Saunders; 2000. p. 4917-4939.
    7. Ryan ET. Tropical and travel medicine: literature alert.  Current Infectious Disease Reports 1999:1(5):411-412.
    8. Ryan ET. Tropical and travel medicine: literature alert.  Current Infectious Disease Reports 2000:1(2):3-4.
    9. Ryan ET.  Immunization. In:  Gorroll AH, Mulley Jr AG, eds.  Primary Care Medicine: Office Evaluation and Management of the Adult Patient.  Fourth Edition. Philadelphia:  Lippincott Williams & Wilkins; 2000. 21-36.
    10. Ryan ET. Ocular disease. In: Guerrant RL, Walker DH, Weller PF, eds. Essentials of Tropical Infectious Diseases. Philadelphia: Churchill Livingstone; 2001: 78-87.
    11. Ryan ET, Salam MA. Cholera. In: Katz S, Gershon A, Hotez P, eds. Krugman’s Infectious Diseases of Children, Eleventh Edition.  Philadelphia: Harcourt Health Sciences, 2004;35-46.
    12. Carroll D, Gardner P, Kay BA, Osterholm M, Ryan ET. Transformation of the developing world: socioeconomic matrix. Emerg Infect Dis. 2004;10:2049.
    13. Ryan ET.  Immunization. In:  Gorroll AH, Mulley Jr AG, eds.  Primary Care Medicine: Office Evaluation and Management of the Adult Patient.  Fifth Edition. Philadelphia:  Lippincott Williams & Wilkins, 2005: 27-42.
    14. Chung V, Armstrong EJ, Samuelson J, Ryan ET. Pharmacology of Parasitic Infections. In: Golan DE, Tashjian AH Jr, Armstrong EJ, Galanter JM, Armstrong AW, Arnaout RA, Rose HS, eds.  Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. Baltimore:  Lippincott Williams & Wilkins, 2005: 587-602. 
    15. Ryan ET, Durand ML.  Ocular disease. In:  Guerrant RL, Walker DH, Weller PF, eds.  Tropical Infectious Diseases: Principles, Pathogens, and Practice. Second Edition.  New York: Elsevier, 2006: 1554-1600.
    16. Ryan ET, Murray M.  Epidemiology and Biostatistics. In:  Guerrant RL, Walker DH, Weller PF, eds.  Tropical Infectious Diseases: Principles, Pathogens, and Practice. Second Edition.  New York: Elsevier, 2006: 19-25.
    17. Ivers LC, Ryan ET. Pharmacology of Parasitic Infections. In: Golan DE, Tashjian AH Jr, Armstrong EJ, Galanter JM, Armstrong AW, Arnaout RA, Rose HS, eds.  Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. Second Edition. Baltimore:  Lippincott Williams & Wilkins, 2007:  631-650. 
    18. Ivers LC, Ryan ET. Protozoal infections of the thorax. In:  Fishman AP, Fishman JA, Grippi MA, Kaiser LB, Senior RM, eds.  Fishman’s Pulmonary Diseases and Disorders. Fourth Edition.  New York: McGraw-Hill, 2008: 2397-2411.
    19. Ryan ET, Durand ML.  Parasitic infections and the eye. In:  Albert DM, Miller JW, eds.  Albert & Jakobiec's: Principles and Practice of Ophthalmology.  Saunders-Elsevier, 3rd Edition, 2008:  4751-4773.
    20. Hill DR, Ryan ET. Diet and education about risks. In:  Ericsson CD, DuPont HL, Steffen R, eds.  Travelers’ diarrhea. 2nd Edition. BC Decker, 2008: 180-190.
    21. Ryan ET. Book Review:  Trachoma- A Blinding Scourge from the Bronze Age to the Twenty-First Century. Hugh R. Taylor. N Engl J Med. 2008; 338:1872-1873.
    22. Larocque RL, Ryan ET.  Immunization. In:  Gorroll AH, Mulley Jr AG, eds.  Primary Care Medicine: Office Evaluation and Management of the Adult Patient.  Sixth Edition. Philadelphia:  Lippincott Williams & Wilkins, 2009: 27-49.
    23. Ghose C, Calderwood SB, Ryan ET. Cholera. In:  Stanberry LR, Barrett ADT, eds. Vaccines for Biodefense and Emerging Infectious Diseases.  Elsevier, 2009: 870-891.
    24. LaRocque EC, Ryan ET. Respiratory Infection. In:  CDC Health Information for International Travel 2010. Elsevier, 2009: 177-181.
    25. Ryan ET, Murray M.  Epidemiology and Biostatistics. In:  Guerrant RL, Walker DH, Weller PF, eds.  Tropical Infectious Diseases: Principles, Pathogens, and Practice. Third Edition.  New York: Elsevier, 2011: 11-16.
    26. Ivers LC, Ryan ET. Pharmacology of Parasitic Infections. In: Golan DE, Tashjian AH Jr, Armstrong EJ, Galanter JM, Armstrong AW, Arnaout RA, Rose HS, eds.  Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. Third Edition. Baltimore:  Lippincott Williams & Wilkins, 2012:  629-648.
    27. Ryan ET, Durand ML.  Ocular disease. In:  Guerrant RL, Walker DH, Weller PF, eds.  Tropical Infectious Diseases: Principles, Pathogens, and Practice. Third Edition.  New York: Elsevier, 2011:991-1016.
    28. LaRocque RC, Ryan ET, Calderwood SB.  Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning.  In:  Harrison's Principles of Internal Medicine, 18th Edition.  McGraw Hill, 2012;1084-1090.
    29. Waldor M, Ryan ET.  Cholera and Other Vibrioses.  In:  Harrison's Principles of Internal Medicine, 18th Edition.  McGraw Hill, 2012: 1289-1295.
    30. LaRocque EC, Ryan ET. Respiratory Infection. In:  CDC Health Information for International Travel 2012; Oxford University Press, 2012; 69-71.
    31. Bloom A, Ryan ET. Albendazole. In: Hunter's Tropical Medicine, 9th Edition. Saunders-Elsevier, London, 2013; 1088-90.
    32. Bloom A, Ryan ET. Mebendazole. In: Hunter's Tropical Medicine, 9th Edition. Saunders-Elsevier, London, 2013; 1086-88.
    33. Bloom A, Ryan ET. Dapsone. In: Hunter's Tropical Medicine, 9th Edition. Saunders-Elsevier, London, 2013; 1108-10.
    34. Bloom A, Ryan ET. Pentamidine. In: Hunter's Tropical Medicine, 9th Edition. Saunders-Elsevier, London, 2013; 1104-06.
    35. Bloom A, Ryan ET. Nitazoxanide. In: Hunter's Tropical Medicine, 9th Edition. Saunders-Elsevier, London, 2013; 1106-08.
    36. Ryan ET. Miscellaneous Tissue Protozoa. In: Hunter's Tropical Medicine, 9th Edition. Saunders-Elsevier, London, 2013; 791.
    37. Ryan ET.  The cholera pandemic, still with us after half a century: time to rethink. PLoS Negl Trop Dis 5(1): 2011.  e1003. doi:10.1371/journal.pntd.0001003
    38. LaRocque EC, Ryan ET. Respiratory infection. In:  CDC Health Information for International Travel 2014, Oxford University Press; 2013:  76-78.
    39. Larocque RL, Ryan ET.  Immunization. In:  Gorroll AH (ed).  Primary Care Medicine: Office Evaluation and Management of the Adult Patient.  7th Edition. Philadelphia:  Wolters Klower Health, 2014:  23-40.
    40. Ivers LC, Ryan ET.  Protozoal infections of the thorax. In:  Fishman AP, Fishman JA, Grippi MA, Kaiser LB, Senior RM, eds.  Fishman’s Pulmonary Diseases and Disorders. Fifth Edition. New York, McGraw Hill. (in press).
    41. Waldor MK, Ryan ET.  Cholera.  Principals and Practice Infectious Diseases; Mandell, Douglas, Bennett, Eds. Bennett JE, Dolin R, Blaser MJ, 8th Edition; Saunders-Elsevier (in press). 2014.  2471-2479.
    42. Harris JB, Ryan ET.  Enteric fevers and other causes of fever and abdominal symptoms.  Principals and Practice Infectious Diseases; Mandell, Douglas, Bennett, Eds. Bennett JE, Dolin R, Blaser MJ, 8th Edition; Saunders-Elsevier (in press). 2014.  1270-1282.
    43. Ryan ET. ASTMH Presidential Address: Eyes on the prize: lessons from the cholera wars for modern scientists, physicians and public health officials. Am. J. Trop. Med. Hyg., 89(4), 2013, pp. 610–614.
    44. Ryan ET. The intestinal pathobiome: its reality and consequences among infants and young children in resource-limited settings. J Infect Dis. 2013 Dec;208(11):1732-3. 
    45. LaRocque RC, Ryan ET, Calderwood SB.  Acute infectious diarrheal diseases and bacterial food poisoning.  In:  Harrison's Principles of Internal Medicine, 19th Edition.  McGraw Hill (in press).
    46. Keusch GT, Rosenberg IH, Denno DM, Duggan C, Guerrant RL, Lavery JV, Tarr PI, Ward HD, Black RE, Nataro JP, Ryan ET, Bhutta ZA, Coovadia H, Lima A, Ramakrishna B, Zaidi AKM, Burgess DCH, Brewer T. Implications of acquired environmental enteric dysfunction for growth and stunting in infants and children living in low- and middle-income countries. Food and Nutrition Bulletin 2013; 34 (3). 357-364.
    47. LaRocque RC, Ryan ET. Respiratory infections. In: Zuckerman J,  Brunette G, Leggat P (eds), Essential Travel Medicine, Wiley-Blackwell (in press).
    48. Waldor M, Ryan ET.  Cholera and Other Vibrioses.  In:  Harrison's Principles of Internal Medicine, 19th Edition.  McGraw Hill, (in press).
    49. Blazes DL, Riddle MS, Ryan ET. The local importance of global infectious diseases. Trop Dis Trav Med Vaccines. 2015; 1:5.
    50. LaRocque EC, Ryan ET. Respiratory infection. In:  CDC Health Information for International Travel 2016, Oxford University Press, 2016:  78-80.
    51. Ryan ET. Cost analysis of travel medicine. In:  CDC Health Information for International Travel 2016, Oxford University Press 2016:  40-41.
    52. Ivers LC, Ryan ET. Pharmacology of Parasitic Infections. In: Golan DE, Tashjian AH Jr, Armstrong EJ, Galanter JM, Armstrong AW, Arnaout RA, Rose HS, eds.  Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. 4th Edition. Baltimore:  Lippincott Williams & Wilkins (in press).
    53. Ryan ET. Antiparasitic Agents.  In: Long SS, Prober CG, Fisher M, eds.  Principle and Practice of Pediatric Infectious Diseases.  5th Edition. Elsevier (in press).
    54. Ryan ET. Troubling news out of Asia on typhoid:  a coming storm. Lancet Infectious Diseases (in press).
    55. Emily P. Hyle, Ryan ET. Cost analysis of travel medicine. In: CDC Health Information for International Travel 2018, Oxford University Press, (in press).
    56. Saleri N, Ryan ET. Respiratory Infections. In: Keystone JS, Freedman DO, Kozarsky PE, Connor BA, Nothdurft HD. Travel Medicine, 4th Edition. Elsevier-Saunders (in press).
    57. LaRocque EC, Ryan ET. Respiratory infection. In: CDC Health Information for International Travel 2018, Oxford University Press, (in press).
    58. Waldor M, Ryan ET. Cholera and Other Vibrioses. In: Harrison's Principles of Internal Medicine, 20th Edition. New York. McGraw Hill (in press).
    59. Ivers LC, Ryan ET. Pharmacology of Parasitic Infections. In: Golan DE, Armstrong EJ, Armstrong AW, eds.  Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. 4th Edition. Philadelphia:  Wolters Kluwer 2017: 674-693.
    60. Ryan ET. Antiparasitic Agents.  In: Long SS, Prober CG, Fisher M, eds.  Principle and Practice of Pediatric Infectious Diseases.  5th Edition. Elsevier 1567-1587.
    61. Ryan ET. Troubling news out of Asia on typhoid:  a coming storm. Lancet Infect Dis. 2016 Jan 19. pii: S1473-3099(15)00542-3.
    62. Emily P. Hyle, Ryan ET. Cost analysis of travel medicine. In:  CDC Health Information for International Travel 2018, Oxford University Press, 30-32.
    63. Saleri N, Ryan ET. Respiratory Infections. In:  Keystone JS, Freedman DO, Kozarsky PE, Connor BA, Nothdurft HD. Travel Medicine, 4th Edition.  Elsevier-Saunders (in press).
    64. LaRocque EC, Ryan ET. Respiratory infection. In:  CDC Health Information for International Travel 2018, Oxford University Press, 66-69.
    65. Waldor M, Ryan ET.  Cholera and Other Vibrioses.  In:  Harrison's Principles of Internal Medicine, 20th Edition. New York. 2018. McGraw Hill, 1186-1192.
    66. Bloom A, Ryan ET. Albendazole (Chapter 162). In: Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan, DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020; 1141-43.
    67. Bloom A, Ryan ET. Mebendazole (Chapter 169). In: Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan, DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020; 1157-58.
    68. Bloom A, Ryan ET. Dapsone (Chapter 165). In: Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan, DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020; 1149-50.
    69. Bloom A, Ryan ET. Pentamidine (Chapter 173). In: Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan, DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020; 1165-66.
    70. Bloom A, Ryan ET. Nitazoxanide (Chapter 172). In: Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan, DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020; 1163-64.
    71. Ryan ET, Magill A. Pentavalent antimony (Chapter 174). In: Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan, DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020; 1167-1168.
    72. Waldor MK, Ryan ET.  Cholera.  Principals and Practice Infectious Diseases; Mandell, Douglas, Bennett, Eds. Bennett JE, Dolin R, Blaser MJ, 9th Edition (in press).
    73. Andrews J, Harris JB, Ryan ET.  Typhoid fever, paratyphoid fever, and typhoidal fevers. Principals and Practice Infectious Diseases; Mandell, Douglas, Bennett, Eds. Bennett JE, Dolin R, Blaser MJ, 9th Edition; Saunders-Elsevier (in press).
    74. Larocque RL, Ryan ET.  Immunization. In:  Gorroll AH (ed).  Primary Care Medicine: Office Evaluation and Management of the Adult Patient.  8th Edition. Philadelphia:  Wolters Klower Health (in press).
    75. LaRocque EC, Ryan ET. Respiratory infection. In:  CDC Health Information for International Travel 2020, Oxford University Press (in press).
    76. Ryan ET. Toxocariasi. (Chapter 120). In: Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan, DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020; 885-887.
    77. Ryan ET, Fawzi W. Nutrition: General Principles (Chapter 142). In: Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan, DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020; 1033.
    78. Gotuzzo E, Ryan ET. Brucellosis (Chapter 75). In: Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan, DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020; 617-618.
    79. Leung DT, LaRocque RC, Ryan ET. Travel Medicine. Annals Internal Med. 2018;168(1):ITC1-ITC16.
    80. Siedner MJ, Ryan ET, Bogoch II. Gone or forgotten? The rise and fall of Zika virus. Lancet Public Health. 2018 Mar;3(3):e109-e110.
    81. Weil AA, Ryan ET. Cholera: recent updates. Curr Opin Infect Dis. 2018 Oct;31(5):455-461.
    82. Andrews JR, Baker S, Marks F, Alsan M, Garrett D, Gellin BG, Saha SK, Qamar FN, Yousafzai MT, Bogoch II, Antillon M, Pitzer VE, Kim JH, John J, Gauld J, Mogasale V, Ryan ET, Luby SP, Lo NC. Typhoid conjugate vaccines: a new tool in the fight against antimicrobial resistance. Lancet Infect Dis. 2018 Aug 28. pii: S1473-3099(18)30350-5.
    83. Andrews JR, Qamar FN, Charles RC, Ryan ET. Extensively Drug-Resistant Typhoid — Are Conjugate Vaccines Arriving Just in Time? N Engl J Med 2018; 379 (16): 1493-1495.
    84. Bogoch I, Ryan ET, Durand M. Systemic Parasitic Infections and the Eye. In: Albert and Jakobiec’s Principles and Practices of Ophthalmology, 4th Edition. Editors: D Albert, J Miller, D Azar and LH. Young. Springer Nature (in press).
    85. Weil A, Ryan ET. Cholera. In: Netter’s Infectious Diseases, 2nd Ed. Editors: EC Jong, DL Stevens. Elsevier (in press).
    86. Ryan ET, Gutman JR, Chancey RJ. Antiparasitic Agents. In: Long SS, Prober CG, Fisher M, eds.  Principle and Practice of Pediatric Infectious Diseases.  6th Elsevier (in press).
    87. Ivers LC, Ryan ET. Protozoal infections of the thorax. In:  Grippi MA, Pack AI, Kotloff R, Dela Cruz C, Antin-Ozerkis D, Kotton C. eds.  Fishman’s Pulmonary Diseases and Disorders. Sixth Edition. McGraw Hill. (in press).
    UpToDate

    Author:

    1. Ryan ET, Andrews J. Epidemiology, microbiology, clinical manifestations, and diagnosis of enteric (typhoid and paratyphoid) fever. Up-To-Date. 2017-
    2. Ryan ET, Andrews J. Treatment and prevention of enteric fever (typhoid and paratyphoid) fever. Up-To-Date. 2017-
    3. Ryan ET, Andrews J. Pathogenesis of enteric fever (typhoid and paratyphoid) fever. Up-To-Date. 2017-
    Textbooks
    1. Hunters's Tropical Medicine and Emerging Infectious Diseases, Editors: A Magill, ET Ryan, D Hill, T Solomon. 9th Edition, Saunders-Elsevier, London, 2013 (ISBN: 978-1-4160-4390-4).
    2. Hunter's Tropical Medicine and Emerging Infectious Diseases, Editors: ET Ryan (lead editor), DR Hill, T Solomon, NE Aronson, TP Endy. 10th Edition, Elsevier, 2020 (ISBN: 978-0-323-55512-8).
    Clinical Communications/Case Reports
    1. Moore AC, Ryan ET, Waldron MA.  Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 20-2002. A 37-year-old man with fever, hepatosplenomegaly, and a cutaneous foot lesion after a trip to Africa. N Engl J Med. 2002;346:2069-76.
    2. Brainard DM, Ryan ET.  Images in clinical medicine. Thoracic echinococcosis. N Engl J Med. 2003;348:528.
    3. Kao AY, Munandar R, Ferrara SL, Systrom DM, Sheridan RL, Cash SS, Ryan ET.  Case records of the Massachusetts General Hospital. Case 19-2005. A 17-year-old girl with respiratory distress and hemiparesis after surviving a tsunami. N Engl J Med. 2005; 352: 2628-2636.
    4. Ryan ET, Felsenstein D, Aquino SL, Branda JA, Morgan JG.  Case records of the Massachusetts General Hospital. Case 39-2005. A 63-year-old woman with a positive serologic test for syphilis and persistent eosinophilia. N Engl J Med 2005; 353:2697-2705.
    5. Ryan ET, Aquino SL, Kradin RL.  Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 29-2007.  A 51-year old man with gastric cancer and lung nodules. N Engl J Med. 2007; 357: 61-68.
    6. Ryan ET, Madoff LC, Ferraro MJ.  Case records of the Massachusetts General Hospital. Case 20-2011. A 30-year-old man with diarrhea after a trip to the Dominican Republic.  N Engl J Med. 2011 Jun 30;364(26):2536-41. PMID: 21714651
    7. Ryan ET, Cronin CG, Branda J.  Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case -2010.  A 34-year old man with paralysis and diarrhea. N Engl J Med. 2011 Dec 15;365(24):2306-16.
    8. Kitchens WH, Liu C, Ryan ET, Fernandez-Del Castillo C. Hepatic hydatid cyst: a rare cause of recurrent pancreatitis.  J Gastrointest Surg. 2014 Aug 23.
    9. Lammert S, Ryan ET, LaRoque RC. JAMA PATIENT PAGE. Safe and Healthy International Travel. JAMA. 2015 Dec 15;314(23):2580.
    10. Chen ST, Cahalane AM, Ryan ET, Foreman RK. Case 2-2019: A 36-Year-Old Man with Rash, Abdominal Pain, and Lymphadenopathy. N Engl J Med. 2019 Jan 17;380(3):275-283.

    Edward T. Ryan, MD

    The ten members of the Ryan Laboratory pose together.
    Ryan Laboratory group members

    Edward T. Ryan, M.D. is the Director of Global Infectious Diseases at Massachusetts General Hospital, Professor of Medicine at Harvard Medical School, and Professor of Immunology and Infectious Diseases at Harvard School of Public Health. Dr. Ryan received his Bachelor’s degree in Biochemical Sciences from Princeton University, and a Doctorate in Medicine from Harvard University. He performed medical residency and fellowship training in infectious diseases at Mass General. Dr. Ryan received additional training in tropical medicine and infectious diseases at the London School of Hygiene & Tropical Medicine, was a Fellow in Human Rights & Medicine, Columbia University, and was an International Fellow, International Centre for Diarrhoeal Disease Research (ICDDR, B), Dhaka, Bangladesh.

    Dr. Ryan's research focuses on clinical studies of illnesses associated with residing in, immigrating from, or traveling through resource-limited settings. His research is funded by the U.S. National Institute of Allergy and Infectious Diseases (NIAID) and the U.S. Centers for Disease Control & Prevention (CDC). Dr. Ryan is the principal investigator on research projects focusing on enteric vaccine development, host-pathogen studies on V. cholerae (the cause of cholera) and Salmonella enterica serovar Typhi (the cause of typhoid fever). Particular areas of focus include the application of high throughput genomic, proteomic, immunoproteomic, and web-based platform technologies to these illnesses. Dr. Ryan is also the Director of Global TravEpiNet, a CDC-supported national consortium focusing on global infectious diseases and evaluating vaccination strategies and use among global international travelers. He is the principal investigator and program director for a Fogarty International Center, National Institutes of Health (NIH)-sponsored Training Program in Vaccine Development and Public Health between Harvard, Mass General and the ICDDR,B in Dhaka, Bangladesh. Dr. Ryan teaches tropical medicine and infectious diseases in the core curricula at Harvard Medical School, Harvard T.H. Chan School of Public Health and Harvard College, teaches students, residents and fellows at Mass General, and teaches in a number of post-graduate courses at Harvard Medical School and internationally.

    Dr. Ryan has served on expert and advisory committees for the Institute of Medicine-National Academy of Sciences, U.S. Centers for Disease Control & Prevention, chaired the Clinical Research and Field Studies of Infectious Diseases Study section of the US NIH from 2006-2008, currently chairs the Standards and Treatment Guidelines Committee of the American Society of Tropical Medicine & Hygiene (ASTMH), and served as ASTMH President from 2009-2010. Dr. Ryan has been elected to Fellowship of the American College of Physicians, the Infectious Diseases Society of America, the American Society of Tropical Medicine & Hygiene, and the American Academy of Microbiology, and has published over 200 peer-reviewed journal articles and book chapters on enteric infections, infectious diseases, vaccines, and tropical medicine. Dr. Ryan is a Senior Editor of Hunter's Tropical Medicine, 9th Edition.

    Learn more about Edward T. Ryan, MD.

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