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About the Condition

Peripheral nerves, the nerves outside of the spinal cord which provide movement and feeling in many different parts of the body, are vulnerable to compression. If a nerve in one of those vulnerable regions becomes injured or inflamed, it may begin to swell and become compressed. This pinching of the nerve will decrease blood flow in the nerve over time. The nerve will become sticky and no longer glide through certain narrow anatomical areas, known as “pinch points,” and as a result, the nerve will begin to undergo changes internally.

At first, the myelin wrapped around the nerve fibers for insulation will lessen, creating symptoms of altered sensations such as:

  • Aching pain in the region
  • Burning
  • Tingling
  • Weakness in the affected muscles

As the compression worsens, these symptoms often progress to numbness in the region and the muscles begin to atrophy. If these symptoms are recognized and treated, the nerve can heal, the tingling and abnormal feelings can improve, and weakness can get better. Even in advanced cases where there is numbness and muscle atrophy, the sensation and the muscle strength can often improve with treatment.

Treatment Options

Once nerve compression is recognized, it can often be treated with non-invasive means such as splinting or steroid injections. In certain circumstances, surgery may be recommended. Many nerve compression syndromes, such as carpal tunnel (at the wrist) and cubital tunnel (at the elbow), particularly when they are caught early, can respond well to temporary immobilization of the joints to avoid undue pressure on the affected nerves. In more mild cases, this treatment may begin immediately after a patient’s evaluation. Steroid injection, in the case of carpal tunnel syndrome, is also an effective option in less severe cases.

When these treatments are not effective, surgery to relieve the nerve compression is recommended. During surgery, the structures that are compressing the nerve are surgically released to allow for better blood flow within the nerve. This surgical release of the nerve aids in healing the nerve and in preventing further injury.

In rare cases, nerve compression can reoccur after surgical treatment due to excessive scar formation or due to the nerve scarring to the overlying skin. In these cases, nerves must again be surgically released from scar in a procedure termed a neurolysis. In such cases, either local tissue or biocompatible materials are used to wrap the nerve to protect it from further tethering in scar tissue.


Although it may take weeks or months for the sensation and the muscle strength to recover after nerve release, typically patients notice decreased symptoms of pain, burning and tingling immediately following surgery. There is soreness expected at the operative site which will gradually improve over several weeks. If there is numbness and muscle atrophy prior to surgery, these symptoms improve over a longer period of time because of the severity of the nerve damage from compression.

Patient Resources: Common Compression Neuropathies

Carpal Tunnel Syndrome PDF
Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

A one-page explanation of Carpal Tunnel Syndrome

Cubital Tunnel Syndrome PDF
Cubital Tunnel Syndrome

Cubital Tunnel Syndrome

Information from the American Society of Surgery for the Hand



When numbness and tingling aren’t caused by Carpal Tunnel Syndrome