Cellular Immunotherapy Program


Contact Information
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Explore the Cellular Immunotherapy Program
Overview
The mission of the Mass General Cellular Immunotherapy Program is to invent, develop, administer, and understand engineered immune effector cells. Our approach is to expand cellular engineering and immunotherapy research by bringing together physicians and laboratory scientists focused on immune cell engineering and its clinical effects. We aim to enhance the cohesion between biological, translational, and clinical aspects of cell engineering to implement safe and potent immunotherapies, with the ultimate goal of developing curative treatments for cancer and other diseases.
Our objectives:
We aim to enhance the cohesion between biological, translational, and clinical aspects of cell engineering to implement safe and potent immunotherapies.
- Bring together clinical researchers who administer, manage, and/or investigate immune effector cells as a therapeutic modality
- Enable translational research and collaboration
- Optimize immune monitoring and laboratory correlatives of clinical observations
- Promote cellular therapy education through education sessions
- Provide high quality care and management of patients receiving cellular therapies
- Obtain and maintain FACT accreditation for the administration of immune effector cells
- Invent and develop novel forms of cellular engineering that will become the next generation of immune cell therapies
Clinical Trials
View Cellular Therapy clinical trials.
CAR T-Cell Therapies
The Mass General Cancer is an authorized treatment center for two FDA approved CAR T-cell therapies for adult patients with lymphoma, Yescarta and Kymriah. Learn more.
Meet the Team
Lead by Marcela Maus, MD, PhD, the Cellular Immunotherapy Program brings together physicians and laboratory scientists focused on immune cell engineering and its clinical effects.
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- Director, Cellular Immunotherapy Program
- Assistant Professor of Medicine, Harvard Medical School
Videos
Of the many different approaches to activate the body’s immune system against cancer, CAR T-cell therapy is one of the most high tech and powerful treatments.
Marcela V. Maus, MD, PhD, Director of the Cellular Immunotherapy Program at the Mass General Cancer Center, was awarded a 2017 Stand Up to Cancer Innovative Research Grant for her work on "Potentiating Novel Engineered Cellular Therapies for Solid Tumors."
Kiss 108 FM’s Billy Costa talks with four experts from the Mass General Cancer Center to learn about what CAR T-cell therapy is and what impact it has on both patients and the medical community.
Kiss 108 FM’s Billy Costa gets a doctor’s perspective of CAR T-cell therapy with Mass General Cancer Center’s clinical director for the Center of Lymphoma, Dr. Jeremy Abramson.
Kiss 108 FM’s Billy Costa sits down with Dr. Marcela Maus, director of cellular immunotherapy at the Mass General Cancer Center, and discusses what CAR T-cell therapy is, who is eligible for treatments, and the future direction of CAR T-cell therapy.
Kiss 108 FM’s Billy Costa discusses CAR T-cell therapy with Mass General Cancer Center’s Dr. Matthew Frigault, medical oncologist and administrative director for Cellular Therapy Services, who explains how this therapy has the potential to impact patients in immense ways.
Watch how Mass General patient Jenn Gilmann has already benefited from immunotherapy.
Resources
Clinical Trials
View Cellular Therapy clinical trials.
CAR T-Cell Therapies
View CAR T-Cell Therapies.
Publications
View publications by Marcela Maus, MD, PhD on PubMed.
FACT Standards
FACT Standards for Immune Effector Cells.
FACT information
The why, what, and how of the new FACT standards for immune effector cells.
Maus Lab
Learn about the Maus laboratory.
Immune Monitoring Lab
Learn about the Immune Monitoring laboratory.
Cellular Therapy & Transplantation Lab
Learn about the Cellular Therapy & Transplantation Laboratory.
Blood Transfusion Service
Learn about Mass General's Blood Transfusion Service.
Honors & Awards
View Cellular Immunotherapy Program team members honored for their commitment to the fight against cancer.
Marcela V. Maus, MD, PhD
As the director of the Cellular Immunotherapy Program at the Mass General Cancer Center, Marcela Maus, MD, PhD, is following a childhood dream of fixing genes gone wrong in the pursuit of a cure for cancer.

Cellular Therapy and Transplantation Laboratory
The CTTL team plays an integral part in stem cell processing, transplant infusions and bone marrow harvests. Technologists also participate in numerous immunotherapy clinical trials to aid in the progression of research and improve patients’ lives.

Featured Articles
- Immune therapy takes a 'BiTE' out of brain cancer
- The Solid Tumor Barrier
- Researchers Explore CAR-T Cells’ Potential
- Cancer Researcher Teamed Up With Superheroes
- Immunotherapy Effort Seeks New Cancer Targets
- Immunotherapy Efforts Advances on Multiple Fronts
- Cellular Immunotherapy Expert Explains CAR T-Cell Therapy Excitement
- CAR-T engineering of patients’ own T cells for cancer therapy gains traction
- For Some, Cutting-Edge 'CAR-T' Treatment Unleashes 'Pac-Man' Cells Against Blood Cancer
- Guest commentary: Early trials support use of CAR T-cell therapy in glioblastoma
- Stand Up To Cancer Awards Innovative Research Grants in Immuno-oncology to 10 Early-career Scientists
participated in Clinical Trials at the Mass General Cancer Center last year
This helped lead to new knowledge and breakthrough therapies.
Center for Cancer Research
The scientific engine for discovery for the Mass General Cancer Center.
Contact the Cancer Center
Contact the Mass General Cancer Center to make an appointment or learn more about our programs.