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Center for Engineering in Medicine
The research thrust of the Cell and Genetic Engineering Group at the Center for Engineering in Medicine is to investigate the role of mesenchymal stromal cells in regenerative medicine and applied immunology.
•Nima Saeidi, PhD•Martin Yarmush, MD, PhD •Memet Toner, PhD•Ron Tompkins, MD, ScD •Shannon N. Tessier, PhD •Irit Adini, PhD
New medicines that deliver human cells and/or genes are transforming our ability to combat disease. This research thrust is poised to discover, characterize and test new gene and cell therapeutics in pre-clinical studies.
We focus on the design and creation of genetic constructs, viral and non-viral delivery systems, and engineered cell lines for translation in the fields of immunology, oncology and stem cell biology.
The group also creates companion cell and tissue systems to model disease states and screen for new targets. A multi-disciplinary approach using methods of computational/synthetic biology, biomedical materials and devices and drug delivery is emphasized in this research.
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