What are the symptoms of Beckwith-Wiedemann syndrome?

Symptoms of Beckwith-Wiedemann syndrome vary from person to person. The most common symptoms of the disorder include:

  • Overgrowth of body parts (hypertrophy)
  • Large body size for a newborn
  • Large tongue size that might make it difficult to breathe or eat
  • Pits or creases in earlobes
  • Low blood sugar
  • Abdominal wall defects, such as omphalocele (organs poke out from the belly button at birth) or umbilical hernia (a bulge is located near or under the abdomen)
  • Larger than normal organs in the abdomen
  • Abnormal heart or kidneys
  • Scoliosis if only one side of the body is affected (hemihypertrophy)

Beckwith-Wiedemann syndrome can also increase the risk of certain childhood cancers, so it is important for your child to have regular tumor screenings. By the time affected children are teenagers, their risk of cancer will have fallen to that of the normal population.

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