A new study demonstrated for the first time an effective method of increasing bone mineral density in girls with anorexia nervosa.
Departments, Centers, & Programs:
Pediatric Endocrine Associates
55 Fruit Street
Boston, MA 02114-2696
- MPH, Harvard T. H. Chan School of Public Health
- MBBS, SCB Medical College
- Residency, Maimonides Medical Center
- Fellowship, Massachusetts General Hospital
American Board Certifications
- Pediatric Endocrinology, American Board of Pediatrics
Accepted Insurance Plans
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Research within the Pediatric Endocrine-Neuroendocrine-Sports Endocrine Lab aims to further knowledge about endocrine, bone, neurocognitive and neuropsychiatric outcomes in athletes, girls with low-weight eating disorders, teenagers and young adults undergoing bariatric surgery, children with diabetes and those with autism spectrum disorders.
Ongoing studies include the following:
- The Role of Estrogen in the Neurobiology of Eating Disorders: A Study of Cognitive Flexibility and Reward in Eating Disorders
- Homeostatic and Hedonic Food Motivation Underlying Eating Disorder Trajectories
- Bone Metabolism in Adolescents Undergoing Bariatric Surgery
- Determinants of bone microarchitectural compromise in youth with type 1 diabetes
- Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes
- Effects of Anorexia Nervosa on Peak Bone Mass
Selected Original Articles (from over 100)
1. Misra M, Katzman DK, Miller KK, Mendes N, Snelgrove D, Russell M, Goldstein MA, Ebrahimi S, Clauss L, Weigel T, Mickley D, Schoenfeld D, Herzog DB, Klibanski A. Physiologic Estrogen Replacement Increases Bone Density in Adolescent Girls with Anorexia Nervosa. J Bone Miner Res 2011;26:2430-8
2. Ackerman KE, Nazem T, Chapko C, Russell M, Mendes N, Taylor AP, Bouxsein ML, Misra M. Bone Microarchitecture is Impaired in Adolescent Amenorrheic Athletes Compared with Eumenorrheic Athletes and Non-Athletic Controls. J Clin Endocrinol Metab 2011;96:3123-33.
Selected Reviews (from over 50)
1. Misra M, Pacaud D, Petryk A, Collett-Solberg P, Kappy M, on behalf of the D&T Committee of the LWPES. Vitamin D Deficiency in Children and its Management: Review of Current Knowledge and Recommendations. Pediatrics 2008; 122: 398-417.
2. Misra M. Effects of Hypogonadism on Bone Metabolism in Adolescent and Young Adult Women. Nature Reviews Endocrinology 2012;8(7):395-404
3. Misra M, Klibanski A. Endocrine Consequences of Anorexia Nervosa. The Lancet Diabetes and Endocrinology. In Press
1. Smith E, Loeffler J, Misra M, Pomerantz S, Stemmer-Rachamimov A, Post M. Case records of the MGH: Case 37-2008. A 17-year-old boy with a pituitary tumor and skull abnormalities. New Eng J Med 2008;359:2367-77
2. Misra M, Parangi S, Ross D, Sadow P, Shailam R. Case records of the MGH: Case 38-2010: a 13-year-old girl with an enlarging neck mass. New Eng J Med 2010;363:2445-54