Researchers at MassGeneral Hospital for Children have discovered novel genes and pathways related to early stages in the development of celiac disease and the ongoing inflammation and comorbidities associated with the condition.
Departments, Centers, & Programs:
Pediatric Gastroenterology and Nutrition
55 Fruit Street
Boston, MA 02114-2696
- MMSc, Harvard Medical School
- MD, New York Medical College
- Residency, Tufts Medical Center
- Fellowship, Massachusetts General Hospital
American Board Certifications
- Pediatrics, American Board of Pediatrics
- Pediatric Gastroenterology, American Board of Pediatrics
Accepted Insurance Plans
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Dr. Leonard’s research is focused on predicting and preventing celiac disease through precision medicine. Precision medicine is an emerging approach to disease prevention and treatment that takes into account individual variability in genes, environment, and lifestyle.
Her current work includes identifying biomarkers that can predict intestinal healing in patients with celiac disease, building translational models capable of predicting autoimmune disease in high-risk individuals and working with Dr. Alessio Fasano on the NIH-funded Celiac Disease: Genomic Environment Microbiome and Metabolomic Study (CDGEMM).
Dr. Leonard currently holds funding from the NIH (K23DK122127) and was previously funded by the Thrasher Research Fund, the Nutrition Obesity Research Center at Harvard, and the NIH (FDK109620A).
- Patient Education
- Oct | 7 | 2019
The CDGEMM Study enrolls infants who have a parent or sibling diagnosed with CD. The risk of developing CD for these infants is increased by 8-25% over that of the general population. Enrolled children are followed from birth until they reach five years of age.